A node organization in the actomyosin contractile ring generates tension and aids stability
Molecular Biology of the Cell, 2017 During cytokinesis, a contractile actomyosin ring constricts and divides the cell in two. How the ring marshals actomyosin forces to generate tension is not settled.
Sathish Thiyagarajan +2 more
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The Multiple Roles of Cyk1p in the Assembly and Function of the Actomyosin Ring in Budding Yeast [PDF]
Molecular Biology of the Cell, 1999 The budding yeast IQGAP-like protein Cyk1p/Iqg1p localizes to the mother-bud junction during anaphase and has been shown to be required for the completion of cytokinesis.
Li, Rong, Shannon, Katie
core +4 more sources
Assembly and positioning of actomyosin rings by contractility and planar cell polarity
eLife, 2015 The actomyosin cytoskeleton is a primary force-generating mechanism in morphogenesis, thus a robust spatial control of cytoskeletal positioning is essential.
Ivonne M Sehring +7 more
doaj +6 more sources
Myosin cluster dynamics determines epithelial wound ring constriction [PDF]
iScienceSummary: Collection of myosin motors and actin filaments can self-assemble into submicrometric clusters under the regulation of RhoA. Emergent dynamics of these clusters have been reported in a variety of morphogenetic systems, ranging from Drosophila to
Alka Bhat +6 more
doaj +2 more sources
Actomyosin dynamics in detached cells: linking clutch model to cell migration and cytokinesis [PDF]
BMC Molecular and Cell BiologySummary Background Cortical retrograde flow of actomyosin plays a critical role in cell migration and cytokinesis. While such flows have been extensively studied in adherent cells, their underlying mechanisms in non-adherent conditions remain poorly ...
Shigehiko Yumura, Yumi Kikuta, Go Itoh
doaj +2 more sources
Actomyosin ring driven cytokinesis in budding yeast. [PDF]
Semin Cell Dev Biol, 2016 Cytokinesis is the final process in the cell cycle that physically divides one cell into two. In budding yeast, cytokinesis is driven by a contractile actomyosin ring (AMR) and the simultaneous formation of a primary septum, which serves as template for cell wall deposition.
Meitinger F, Palani S.
europepmc +3 more sources
Investigating the roles of turnover and mobility in the actomyosin ring of Schizosaccharomyces pombe [PDF]
In many eukaryotes cytokinesis is facilitated by the contraction of an actomyosin ring. The exact mechanisms that lead to this contractility are unknown, although a number of models posit that actin turnover in the ring is essential.
Cheffings, Thomas H.
core +3 more sources
Dynamics and Stability of the Contractile Actomyosin Ring in the Cell [PDF]
Physical Review Letters, 2022 Contraction of the cytokinetic ring during cell division leads to physical partitioning of a eukaryotic cell into two daughter cells. This involves flows of actin filaments and myosin motors in the growing membrane interface at the mid-plane of the dividing cell.
Mainak Chatterjee +3 more
openaire +3 more sources
A novel checkpoint pathway controls actomyosin ring constriction trigger in fission yeast. [PDF]
Elife, 2020 In fission yeast, the septation initiation network (SIN) ensures temporal coordination between actomyosin ring (CAR) constriction with membrane ingression and septum synthesis. However, questions remain about CAR regulation under stress conditions.
Edreira T +3 more
europepmc +6 more sources
Self-organized spatial targeting of contractile actomyosin rings for synthetic cell division
Nature CommunicationsA key challenge for bottom-up synthetic biology is engineering a minimal module for self-division of synthetic cells. Actin-based cytokinetic rings are considered a promising structure to produce the forces required for the controlled excision of cell ...
María Reverte-López +5 more
doaj +5 more sources