Results 21 to 30 of about 6,880 (162)
Reconstitution of contractile actomyosin rings in vesicles [PDF]
Nature Communications, 2020 Abstract One of the grand challenges of bottom-up synthetic biology is the development of minimal machineries for cell division. The mechanical transformation of large-scale compartments, such as Giant Unilamellar Vesicles (GUVs), requires the geometry-specific coordination of active elements, several orders of magnitude larger than ...
Thomas Litschel +8 more
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Motor Activity Dependent and Independent Functions of Myosin II Contribute to Actomyosin Ring Assembly and Contraction in Schizosaccharomyces pombe [PDF]
Current Biology, 2017 Ting Gang Chew +2 more
exaly +2 more sources
Bio-Protocol, 2022 Cytokinesis occurs at the final step of cell division and leads to the separation of daughter cells. It requires assembly and constriction of the actomyosin contractile ring.
Swati Sharma, Richa Rikhy
doaj +1 more source
Myo2p is the major motor involved in actomyosin ring contraction in fission yeast. [PDF]
Curr Biol, 2017 Cytokinesis in many eukaryotes requires an actomyosin-based contractile ring [1]. In fission yeast, cytokinesis involves the type II myosins Myo2p and Myp2p and the type V myosin Myo51p [2]. A recent study by Laplante et al.[3], using deletion mutants of myp2 and myo51 and the mis-sense mutant myo2-E1 [4], concluded that each myosin has distinct ...
Zambon P +3 more
europepmc +5 more sources
Force to divide: structural and mechanical requirements for actomyosin ring contraction. [PDF]
Biophys J, 2013 One of the unresolved questions in the field of cell division is how the actomyosin cytoskeleton remains structurally organized while generating the contractile force to divide one cell into two. In analogy to the actomyosin-based force production mechanism in striated muscle, it was originally proposed that contractile stress in the actomyosin ring is
Mendes Pinto I, Rubinstein B, Li R.
europepmc +4 more sources
A New Membrane Protein Sbg1 Links the Contractile Ring Apparatus and Septum Synthesis Machinery in Fission Yeast. [PDF]
PLoS Genetics, 2016 Cytokinesis in many organisms requires a plasma membrane anchored actomyosin ring, whose contraction facilitates cell division. In yeast and fungi, actomyosin ring constriction is also coordinated with division septum assembly.
Kriti Sethi +10 more
doaj +1 more source
PLoS Genetics, 2023 During C. elegans oocyte meiosis I cytokinesis and polar body extrusion, cortical actomyosin is locally remodeled to assemble a contractile ring that forms within and remains part of a much larger and actively contractile cortical actomyosin network ...
Alyssa R Quiogue +4 more
doaj +1 more source
PP1-Dependent Formin Bnr1 Dephosphorylation and Delocalization from a Cell Division Site. [PDF]
PLoS ONE, 2016 Cell cycle ends with cytokinesis that is the physical separation of a cell into two daughter cells. For faithful cytokinesis, cells integrate multiple processes, such as actomyosin ring formation, contraction and plasma membrane closure, into coherent ...
Minami Orii +3 more
doaj +1 more source
Encapsulated actomyosin patterns drive cell-like membrane shape changes
iScience, 2022 Summary: Cell shape changes from locomotion to cytokinesis are, to a large extent, driven by myosin-driven remodeling of cortical actin patterns.
Yashar Bashirzadeh +2 more
doaj +1 more source
Structure and Constriction Mechanism of the Actomyosin Ring [PDF]
Biophysical Journal, 2018 Cytokinesis is orchestrated by a contractile actomyosin ring, but its structure and mechanism remain elusive. We visualized the 3D structure of the ring in frozen‐hydrated dividing yeast cells by electron cryotomography (ECT). Detailed arrangements of actin filaments within the ring and with respect to the membrane were seen for the first time ...
Nguyen, Lam T. +2 more
openaire +2 more sources