Structure of the fission yeast actomyosin ring during constriction [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 2018 Significance Many eukaryotic cells divide using a contractile actomyosin ring, but its structure is unknown. Here we use new specimen preparation methods and electron cryotomography to image constricting rings directly in 3D, in a near-native state in the model organism Schizosaccharomyces ...
Mithilesh Mishra +2 more
exaly +7 more sources
Equatorial Assembly of the Cell-Division Actomyosin Ring in the Absence of Cytokinetic Spatial Cues [PDF]
Current Biology, 2018 The position of the division site dictates the size and fate of daughter cells in many organisms. In animal cells, division-site placement involves overlapping mechanisms, including signaling from the central spindle microtubules, astral microtubules, and spindle poles and through polar contractions [1-3].
Ting Gang Chew +2 more
exaly +5 more sources
Coordinating septum formation and the actomyosin ring during cytokinesis in Schizosaccharomyces pombe [PDF]
Molecular Microbiology, 2019 SummaryDuring cytokinesis, animal and fungal cells form a membrane furrow via actomyosin ring constriction. Our understanding of actomyosin ring‐driven cytokinesis stems extensively from the fission yeast model system. However, unlike animal cells, actomyosin ring constriction occurs simultaneously with septum formation in fungi. While the formation of
Maitreyi Das
exaly +5 more sources
Curvature-induced expulsion of actomyosin bundles during cytokinetic ring contraction [PDF]
eLife, 2016 Many eukaryotes assemble a ring-shaped actomyosin network that contracts to drive cytokinesis. Unlike actomyosin in sarcomeres, which cycles through contraction and relaxation, the cytokinetic ring disassembles during contraction through an unknown ...
Junqi Huang +9 more
doaj +5 more sources
Assembly and positioning of actomyosin rings by contractility and planar cell polarity
eLife, 2015 The actomyosin cytoskeleton is a primary force-generating mechanism in morphogenesis, thus a robust spatial control of cytoskeletal positioning is essential.
Ivonne M Sehring +7 more
doaj +6 more sources
Who Needs a Contractile Actomyosin Ring? The Plethora of Alternative Ways to Divide a Protozoan Parasite [PDF]
Frontiers in Cellular and Infection Microbiology, 2019 Tansy Hammarton
exaly +2 more sources
Actomyosin ring driven cytokinesis in budding yeast. [PDF]
Semin Cell Dev Biol, 2016 Cytokinesis is the final process in the cell cycle that physically divides one cell into two. In budding yeast, cytokinesis is driven by a contractile actomyosin ring (AMR) and the simultaneous formation of a primary septum, which serves as template for cell wall deposition.
Meitinger F, Palani S.
europepmc +3 more sources
Dynamics and Stability of the Contractile Actomyosin Ring in the Cell [PDF]
Physical Review Letters, 2022 Contraction of the cytokinetic ring during cell division leads to physical partitioning of a eukaryotic cell into two daughter cells. This involves flows of actin filaments and myosin motors in the growing membrane interface at the mid-plane of the dividing cell.
Mainak Chatterjee +3 more
openaire +3 more sources
A novel checkpoint pathway controls actomyosin ring constriction trigger in fission yeast. [PDF]
Elife, 2020 In fission yeast, the septation initiation network (SIN) ensures temporal coordination between actomyosin ring (CAR) constriction with membrane ingression and septum synthesis. However, questions remain about CAR regulation under stress conditions.
Edreira T +3 more
europepmc +6 more sources
Self-organized spatial targeting of contractile actomyosin rings for synthetic cell division
Nature CommunicationsA key challenge for bottom-up synthetic biology is engineering a minimal module for self-division of synthetic cells. Actin-based cytokinetic rings are considered a promising structure to produce the forces required for the controlled excision of cell ...
María Reverte-López +5 more
doaj +5 more sources