Equatorial Assembly of the Cell-Division Actomyosin Ring in the Absence of Cytokinetic Spatial Cues [PDF]
Current Biology, 2018 The position of the division site dictates the size and fate of daughter cells in many organisms. In animal cells, division-site placement involves overlapping mechanisms, including signaling from the central spindle microtubules, astral microtubules ...
Tomoyuki Hatano +2 more
exaly +6 more sources
Curvature-induced expulsion of actomyosin bundles during cytokinetic ring contraction [PDF]
eLife, 2016 Many eukaryotes assemble a ring-shaped actomyosin network that contracts to drive cytokinesis. Unlike actomyosin in sarcomeres, which cycles through contraction and relaxation, the cytokinetic ring disassembles during contraction through an unknown ...
Junqi Huang +9 more
doaj +6 more sources
Actomyosin ring driven cytokinesis in budding yeast. [PDF]
Semin Cell Dev Biol, 2016 Cytokinesis is the final process in the cell cycle that physically divides one cell into two. In budding yeast, cytokinesis is driven by a contractile actomyosin ring (AMR) and the simultaneous formation of a primary septum, which serves as template for ...
Meitinger F, Palani S.
europepmc +4 more sources
Myo2p is the major motor involved in actomyosin ring contraction in fission yeast. [PDF]
Curr Biol, 2017 Cytokinesis in many eukaryotes requires an actomyosin-based contractile ring [1]. In fission yeast, cytokinesis involves the type II myosins Myo2p and Myp2p and the type V myosin Myo51p [2]. A recent study by Laplante et al.
Zambon P +3 more
europepmc +5 more sources
Motor Activity Dependent and Independent Functions of Myosin II Contribute to Actomyosin Ring Assembly and Contraction in Schizosaccharomyces pombe [PDF]
Current Biology, 2017 Cytokinesis depends on a contractile actomyosin ring in many eukaryotes [1, 2, 3]. Myosin II is a key component of the actomyosin ring, although whether it functions as a motor or as an actin cross-linker to exert its essential role is disputed [1, 4, 5].
Saravanan Palani +2 more
exaly +4 more sources
Embryonic ring closure: Actomyosin rings do the two-step [PDF]
Journal of Cell Biology, 2016 Actomyosin rings drive numerous closure processes, but the mechanisms by which they contract are still poorly understood. In this issue, Xue and Sokac (2016. J. Cell Biol.
Martin, Adam C, Adam C. Martin
core +5 more sources
Force to divide: structural and mechanical requirements for actomyosin ring contraction. [PDF]
Biophys J, 2013 One of the unresolved questions in the field of cell division is how the actomyosin cytoskeleton remains structurally organized while generating the contractile force to divide one cell into two.
Mendes Pinto I, Rubinstein B, Li R.
europepmc +5 more sources
Coordinating septum formation and the actomyosin ring during cytokinesis in Schizosaccharomyces pombe [PDF]
Molecular Microbiology, 2019 SummaryDuring cytokinesis, animal and fungal cells form a membrane furrow via actomyosin ring constriction. Our understanding of actomyosin ring‐driven cytokinesis stems extensively from the fission yeast model system. However, unlike animal cells, actomyosin ring constriction occurs simultaneously with septum formation in fungi. While the formation of
Brian S Hercyk, Maitreyi Das
exaly +5 more sources
Hof1 and Rvs167 have redundant roles in actomyosin ring function during cytokinesis in budding yeast. [PDF]
PLoS ONE, 2013 The Hof1 protein (Homologue of Fifteen) regulates formation of the primary septum during cytokinesis in the budding yeast Saccharomyces cerevisiae, whereas the orthologous Cdc15 protein in fission yeast regulates the actomyosin ring by using its F-BAR ...
Pedro Junior Nkosi +3 more
doaj +3 more sources
Structure and Constriction Mechanism of the Actomyosin Ring [PDF]
Biophysical Journal, 2018 Cytokinesis is orchestrated by a contractile actomyosin ring, but its structure and mechanism remain elusive. We visualized the 3D structure of the ring in frozen-hydrated dividing yeast cells by electron cryotomography (ECT).
Swulius, Matthew +2 more
core +3 more sources