Results 41 to 50 of about 6,880 (162)

The Rho1 GTPase controls anillo-septin assembly to facilitate contractile ring closure during cytokinesis

open access: yesiScience, 2023
Summary: Animal cell cytokinesis requires activation of the GTPase RhoA (Rho1 in Drosophila), which assembles an F-actin- and myosin II-dependent contractile ring (CR) at the equatorial plasma membrane.
Sabrya C. Carim, Gilles R.X. Hickson
doaj   +1 more source

The actomyosin ring bulks up [PDF]

open access: yesJ Cell Biol, 2011
![Figure][1] Purple in this heat map indicates that there is more myosin II in a larger contractile ring (left) than in a smaller one (right). Calvert et al. reveal that large fungal cells have more myosin II associated with their contractile rings than do smaller cells, which allows ...
europepmc   +3 more sources

Paxillin-Mediated Recruitment of Calcineurin to the Contractile Ring Is Required for the Correct Progression of Cytokinesis in Fission Yeast

open access: yesCell Reports, 2018
Summary: Paxillin is a scaffold protein that participates in focal adhesion signaling in mammalian cells. Fission yeast paxillin ortholog, Pxl1, is required for contractile actomyosin ring (CAR) integrity and collaborates with the β-glucan synthase Bgs1 ...
Rebeca Martín-García   +8 more
doaj   +1 more source

A tug of war between filament treadmilling and myosin induced contractility generates actin rings

open access: yeseLife, 2022
In most eukaryotic cells, actin filaments assemble into a shell-like actin cortex under the plasma membrane, controlling cellular morphology, mechanics, and signaling.
Qin Ni   +6 more
doaj   +1 more source

Embryonic ring closure: Actomyosin rings do the two-step [PDF]

open access: yesJournal of Cell Biology, 2016
Actomyosin rings drive numerous closure processes, but the mechanisms by which they contract are still poorly understood. In this issue, Xue and Sokac (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201608025) show that actomyosin ring closure during Drosophila melanogaster cellularization uses two steps, only one of which involves Myosin-2.
openaire   +4 more sources

Regulation and Assembly of Actomyosin Contractile Rings in Cytokinesis and Cell Repair [PDF]

open access: yesThe Anatomical Record, 2018
ABSTRACT Cytokinesis and single‐cell wound repair both involve contractile assemblies of filamentous actin (F‐actin) and myosin II organized into characteristic ring‐like arrays. The assembly of these actomyosin contractile rings (CRs) is specified spatially and temporally by small Rho GTPases, which trigger local
Corina Dekraker   +2 more
openaire   +2 more sources

An in vitro culture platform for studying the effect of collective cell migration on spatial self-organization within induced pluripotent stem cell colonies

open access: yesJournal of Biological Engineering, 2023
Highlights • Ring culture system induces distinct changes in actomyosin organization at the iPSC colony edge. • Removal of ring culture system induces collective cell migration at the iPSC colony edge. • Collective cell migration modulates self-organized
Mee-Hae Kim   +4 more
doaj   +1 more source

The Cortical ER Network Limits the Permissive Zone for Actomyosin Ring Assembly [PDF]

open access: yesCurrent Biology, 2010
Precise positioning of the cellular division plane is important for accurate segregation of genetic material and determination of daughter cell fates. Here we report a surprising connection between division site positioning and the organization of the cortical endoplasmic reticulum (ER).
Zhang, Dan   +2 more
openaire   +3 more sources

Rho Family GTPases in Fission Yeast Cytokinesis

open access: yesCommunicative & Integrative Biology, 2019
During cytokinesis, actomyosin ring constriction drives furrow formation. In animal cells, Rho GTPases drive this process through the positioning and assembly of the actomyosin ring, and through extracellular matrix remodeling within the furrow.
Brian Hercyk, Maitreyi Das
doaj   +1 more source

Quantitative analysis of mechanical force required for cell extrusion in zebrafish embryonic epithelia

open access: yesBiology Open, 2017
When cells in epithelial sheets are damaged by intrinsic or extrinsic causes, they are eliminated by extrusion from the sheet. Cell extrusion, which is required for maintenance of tissue integrity, is the consequence of contraction of actomyosin rings ...
Sohei Yamada   +4 more
doaj   +1 more source

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