Results 41 to 50 of about 6,880 (162)
Summary: Animal cell cytokinesis requires activation of the GTPase RhoA (Rho1 in Drosophila), which assembles an F-actin- and myosin II-dependent contractile ring (CR) at the equatorial plasma membrane.
Sabrya C. Carim, Gilles R.X. Hickson
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The actomyosin ring bulks up [PDF]
![Figure][1] Purple in this heat map indicates that there is more myosin II in a larger contractile ring (left) than in a smaller one (right). Calvert et al. reveal that large fungal cells have more myosin II associated with their contractile rings than do smaller cells, which allows ...
europepmc +3 more sources
Summary: Paxillin is a scaffold protein that participates in focal adhesion signaling in mammalian cells. Fission yeast paxillin ortholog, Pxl1, is required for contractile actomyosin ring (CAR) integrity and collaborates with the β-glucan synthase Bgs1 ...
Rebeca Martín-García +8 more
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A tug of war between filament treadmilling and myosin induced contractility generates actin rings
In most eukaryotic cells, actin filaments assemble into a shell-like actin cortex under the plasma membrane, controlling cellular morphology, mechanics, and signaling.
Qin Ni +6 more
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Embryonic ring closure: Actomyosin rings do the two-step [PDF]
Actomyosin rings drive numerous closure processes, but the mechanisms by which they contract are still poorly understood. In this issue, Xue and Sokac (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201608025) show that actomyosin ring closure during Drosophila melanogaster cellularization uses two steps, only one of which involves Myosin-2.
openaire +4 more sources
Regulation and Assembly of Actomyosin Contractile Rings in Cytokinesis and Cell Repair [PDF]
ABSTRACT Cytokinesis and single‐cell wound repair both involve contractile assemblies of filamentous actin (F‐actin) and myosin II organized into characteristic ring‐like arrays. The assembly of these actomyosin contractile rings (CRs) is specified spatially and temporally by small Rho GTPases, which trigger local
Corina Dekraker +2 more
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Highlights • Ring culture system induces distinct changes in actomyosin organization at the iPSC colony edge. • Removal of ring culture system induces collective cell migration at the iPSC colony edge. • Collective cell migration modulates self-organized
Mee-Hae Kim +4 more
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The Cortical ER Network Limits the Permissive Zone for Actomyosin Ring Assembly [PDF]
Precise positioning of the cellular division plane is important for accurate segregation of genetic material and determination of daughter cell fates. Here we report a surprising connection between division site positioning and the organization of the cortical endoplasmic reticulum (ER).
Zhang, Dan +2 more
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Rho Family GTPases in Fission Yeast Cytokinesis
During cytokinesis, actomyosin ring constriction drives furrow formation. In animal cells, Rho GTPases drive this process through the positioning and assembly of the actomyosin ring, and through extracellular matrix remodeling within the furrow.
Brian Hercyk, Maitreyi Das
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When cells in epithelial sheets are damaged by intrinsic or extrinsic causes, they are eliminated by extrusion from the sheet. Cell extrusion, which is required for maintenance of tissue integrity, is the consequence of contraction of actomyosin rings ...
Sohei Yamada +4 more
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