Results 61 to 70 of about 7,599 (177)

Formins Determine the Functional Properties of Actin Filaments in Yeast [PDF]

, 2014
The actin cytoskeleton executes a broad range of essential functions within a living cell. The dynamic nature of the actin polymer is modulated to facilitate specific cellular processes at discrete locations by actin-binding proteins (ABPs), including ...
Mulvihill, Daniel P., East, Daniel A., Johnson, Matthew   +2 more
core   +1 more source

Fission yeast septation

Communicative & Integrative Biology, 2016
In animal cells cytokinesis relies on the contraction of an actomyosin ring that pulls the plasma membrane to create a cleavage furrow, whose ingression finally divides the mother cell into two daughter cells.
Juan C. G. Cortés, Mariona Ramos, Masako Osumi, Pilar Pérez, Juan Carlos Ribas   +4 more
doaj   +1 more source

The integrity of the cytokinesis machinery under stress conditions requires the glucan synthase Bgs1p and its regulator Cfh3p. [PDF]

PLoS ONE, 2012
In yeast, cytokinesis requires coordination between nuclear division, acto-myosin ring contraction, and septum synthesis. We studied the role of the Schizosaccharomyces pombe Bgs1p and Cfh3p proteins during cytokinesis under stress conditions.
Mohammad Reza Sharifmoghadam, M-Ángeles Curto, Marta Hoya, Nagore de León, Rebeca Martin-Garcia, Cristina Doncel, M-Henar Valdivieso   +6 more
doaj   +1 more source

An equatorial contractile mechanism drives cell elongation but not cell division.

PLoS Biology, 2014
Cell shape changes and proliferation are two fundamental strategies for morphogenesis in animal development. During embryogenesis of the simple chordate Ciona intestinalis, elongation of individual notochord cells constitutes a crucial stage of notochord
Ivonne M Sehring, Bo Dong, Elsa Denker, Punit Bhattachan, Wei Deng, Birthe T Mathiesen, Di Jiang   +6 more
doaj   +1 more source

Nuc2p, a subunit of the anaphase-promoting complex, inhibits septation initiation network following cytokinesis in fission yeast. [PDF]

PLoS Genetics, 2008
In most cell types, mitosis and cytokinesis are tightly coupled such that cytokinesis occurs only once per cell cycle. The fission yeast Schizosaccharomyces pombe divides using an actomyosin-based contractile ring and is an attractive model for the study
Ting Gang Chew, Mohan K Balasubramanian
doaj   +1 more source

Myosin turnover controls actomyosin contractile instability [PDF]

, 2022
Actomyosin contractile force produced by myosin II molecules that bind and pull actin filaments is harnessed for diverse functions, from cell division by the cytokinetic contractile ring to morphogenesis driven by supracellular actomyosin networks during
Kumar, Lokesh, Balasubramanian, Mohan K., Wang, Shuyuan, O’Shaughnessy, Ben, Junqi Huang, Sathish Thiyagarajan, Ben O'Shaughnessy, Shuyuan Wang, Mohan K. Balasubramanian, Chew, Ting Gang, Ting Gang Chew, Thiyagarajan, Sathish, Lokesh Kumar, Huang, Junqi   +13 more
core   +1 more source

Ect2/Pbl Acts via Rho and Polarity Proteins to Direct the Assembly of an Isotropic Actomyosin Cortex upon Mitotic Entry.

, 2015
Entry into mitosis is accompanied by profound changes in cortical actomyosin organization. Here, we delineate a pathway downstream of the RhoGEF Pbl/Ect2 that directs this process in a model epithelium.
Rosa, André, Pichaud, Franck, Vlassaks, E, Baum, B, Pichaud, F, Rosa, A, Vlassaks, Evi, Baum, Buzz   +7 more
core   +1 more source

TOR complex 2 localises to the cytokinetic actomyosin ring and controls the fidelity of cytokinesis. [PDF]

J Cell Sci, 2016
ABSTRACT The timing of cell division is controlled by the coupled regulation of growth and division. The target of rapamycin (TOR) signalling network synchronises these processes with the environmental setting. Here, we describe a novel interaction of the fission yeast TOR complex 2 (TORC2) with the cytokinetic actomyosin ring (CAR), and
Baker K, Kirkham S, Halova L, Atkin J, Franz-Wachtel M, Cobley D, Krug K, Maček B, Mulvihill DP, Petersen J.   +9 more
europepmc   +4 more sources

Radial contractility of actomyosin rings facilitates axonal trafficking and structural stability

Journal of Cell Biology, 2020
Most mammalian neurons have a narrow axon, which constrains the passage of large cargoes such as autophagosomes that can be larger than the axon diameter. Radial axonal expansion must therefore occur to ensure efficient axonal trafficking. In this study, we reveal that the speed of various large cargoes undergoing axonal transport is significantly ...
Tong Wang, Wei Li, Sally Martin, Andreas Papadopulos, Merja Joensuu, Chunxia Liu, Anmin Jiang, Golnoosh Shamsollahi, Rumelo Amor, Vanessa Lanoue, Pranesh Padmanabhan, Frédéric A. Meunier   +11 more
openaire   +5 more sources

ER-PM Contacts Define Actomyosin Kinetics for Proper Contractile Ring Assembly [PDF]

Current Biology, 2016
The cortical endoplasmic reticulum (ER), an elaborate network of tubules and cisternae [1], establishes contact sites with the plasma membrane (PM) through tethering machinery involving a set of conserved integral ER proteins [2]. The physiological consequences of forming ER-PM contacts are not fully understood.
Zhang, Dan, Bidone, Tamara C., Vavylonis, Dimitrios   +2 more
openaire   +2 more sources