Results 81 to 90 of about 6,880 (162)
Structure and constriction mechanism of the actomyosin ring
, 2017 Cytokinesis is orchestrated by a contractile actomyosin ring, but its structure and mechanism remain elusive. We visualized the 3D structure of the ring in frozen‐hydrated dividing yeast cells by electron cryotomography (ECT). Detailed arrangements of actin filaments within the ring and with respect to the membrane were seen for the first time ...
Nguyen, L. T., Jensen, G. J.
openaire +2 more sources
Bub2 regulation of cytokinesis and septation in budding yeast
BMC Cell Biology, 2009 Background The mitotic exit network (MEN) is required for events at the end of mitosis such as degradation of mitotic cyclins and cytokinesis. Bub2 and its binding partner Bfa1 act as a GTPase activating protein (GAP) to negatively regulate the MEN ...
Park Su Young +4 more
doaj +1 more source
Biophysical processes of morphogenesis in lizard lungs
Developmental Dynamics, EarlyView.Abstract Background The lungs of squamate reptiles (lizards and snakes) are highly diverse, exhibiting single chambers, multiple chambers, transitional forms with two to three chambers, along with a suite of other anatomical features, including finger‐like epithelial projections into the body cavity known as diverticulae.
Kaleb Hill +9 more
wiley +1 more source
Importance of a Myosin II-Containing Progenitor for Actomyosin Ring Assembly in Fission Yeast [PDF]
Current Biology, 2002 An actomyosin-based contractile ring provides the forces necessary for cell cleavage in several organisms [1-3]. Myosin II is an essential component of the actomyosin ring and has also been detected as a "spot" in interphase Schizosaccharomyces pombe cells [4-5]. It is currently unknown if this myosin II-containing spot is important for cytokinesis. In
Wong, Kelvin C.Y. +5 more
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UCS protein Rng3p is essential for myosin-II motor activity during cytokinesis in fission yeast. [PDF]
PLoS ONE, 2013 UCS proteins have been proposed to operate as co-chaperones that work with Hsp90 in the de novo folding of myosin motors. The fission yeast UCS protein Rng3p is essential for actomyosin ring assembly and cytokinesis.
Benjamin C Stark +4 more
doaj +1 more source
A proteomic investigation of forebrain regeneration in the leopard gecko (Eublepharis macularius)
Developmental Dynamics, EarlyView.Our investigation reveals ontogenetic, injury‐ and regeneration‐associated proteomic changes in the leopard gecko forebrain. Abstract Background The ability to replace lost or damaged neurons following an injury is termed reactive neurogenesis. Although reactive neurogenesis has been reported in several lizard species, the molecular mechanisms ...
Alexandra I. Noble +2 more
wiley +1 more source
The Anaphase-promoting Complex Promotes Actomyosin-Ring Disassembly during Cytokinesis in Yeast [PDF]
Molecular Biology of the Cell, 2009 The anaphase-promoting complex (APC) is a ubiquitin ligase that controls progression through mitosis by targeting specific proteins for degradation. It is unclear whether the APC also contributes to the control of cytokinesis, the process that divides the cell after mitosis.
Gregory H, Tully +3 more
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VIEW, EarlyView.Dynamic immuno‐mechanobiomaterials with time‐programmed mechanical adaptation orchestrate host responses through precise mechanotransduction and immune‐stromal regulation. These adaptive biomaterials minimize mechanical mismatch, attenuate the forign dy response and fibrosis, promote angiogenesis and controlled extracellular matrix remodeling, and ...
Gobinath Vellapalayam Manoharan +4 more
wiley +1 more source
Cdk1-dependent phosphorylation of Iqg1 governs actomyosin ring assembly prior to cytokinesis. [PDF]
J Cell Sci, 2014 Contraction of the actomyosin ring (AMR) provides the centripetal force that drives cytokinesis. In budding yeast, assembly and contraction of the AMR is coordinated with membrane deposition and septum formation at the bud neck. A central player in this process is Iqg1, which promotes recruitment of actin to the myosin ring and links AMR assembly with ...
Naylor SG, Morgan DO.
europepmc +3 more sources
British Journal of Pharmacology, EarlyView.Blood vascular permeability is a hallmark of cancer and acts as an active driver of metastatic dissemination. Metastasis accounts for the vast majority of cancer deaths, yet most work has focussed on tumour‐intrinsic traits and angiogenesis, while the specific contribution of endothelial barrier regulation to intravasation and extravasation remains ...
Pierre Boucher +6 more
wiley +1 more source