Results 81 to 90 of about 7,599 (177)
Actomyosin rings constrain CD40 mobility to organize the dendritic cell immunological synapse. [PDF]
Cell Commun SignalAbstract Background The interaction between dendritic cell CD40 and T cell CD40L is critical for dendritic cell licensing and the initiation of adaptive immunity. The spatial organization of CD40 on the dendritic cell surface is thought to dictate its signaling output, yet the underlying ...
Clamagirand CD +5 more
europepmc +2 more sources
From Cytoskeletal Remodeling to Oocyte Quality: The Emerging Role of Mechanics
Advanced Science, EarlyView.Mechanical properties of the oocyte are increasingly recognized as critical determinants of meiotic success and developmental potential. How actomyosin remodeling controls oocyte mechanics, how these properties are altered in pathological conditions, and how they could serve as markers in reproductive medicine are examined.
Anastasia Shihabi +3 more
wiley +1 more source
Advanced Science, EarlyView.PDGFA/PDGFRα signaling recruits CAFs to OSCC nests, and CAF‐OSCC contact drives tumor budding invasion. Mechanistically, heterotypic adhesion via E‐cadherin/integrin α2β1 activates YAP signaling in OSCC cells, inducing EMT. Concurrently, CAFs transfer mitochondria through TNTs, supplying ATP to fuel invasion.
Yufang Liu +17 more
wiley +1 more source
Vrp1p Functions in Both Actomyosin Ring‐Dependent and Hof1p‐Dependent Pathways of Cytokinesis [PDF]
Traffic, 2001 Vrp1p/verprolin/End5p is a Saccharomyces cerevisiae proline‐rich protein, structurally and functionally related to human Wiskott–Aldrich syndrome protein‐interacting protein. Vrp1p is required for viability at 37°C, but not 24°C. Here, we show that loss of Vrp1p (vrp1Δ) leads to a 3–4‐fold delay in cytokinesis, wide bud necks, abnormal ...
S N, Naqvi +4 more
openaire +2 more sources
Wrangling Actin Assemblies: Actin Ring Dynamics during Cell Wound Repair
Cells, 2022 To cope with continuous physiological and environmental stresses, cells of all sizes require an effective wound repair process to seal breaches to their cortex.
Justin Hui +3 more
doaj +1 more source
BMEMat, EarlyView.The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang +6 more
wiley +1 more source
The Role of the Cell Integrity Pathway in Septum Assembly in Yeast
Journal of Fungi, 2021 Cytokinesis divides a mother cell into two daughter cells at the end of each cell cycle and proceeds via the assembly and constriction of a contractile actomyosin ring (CAR).
Cesar Roncero +4 more
doaj +1 more source
Cytometry Part A, EarlyView.ABSTRACT Cell‐in‐cell (CIC) structures are among the most intriguing cellular phenomena occasionally observed in human cancer specimens. Once regarded as incidental findings, accumulating evidence has linked specific CIC subtypes, particularly entosis, to tumor progression and patient prognosis.
Maria V. Leyba‐Mesa +4 more
wiley +1 more source
Bub2 regulation of cytokinesis and septation in budding yeast
BMC Cell Biology, 2009 Background The mitotic exit network (MEN) is required for events at the end of mitosis such as degradation of mitotic cyclins and cytokinesis. Bub2 and its binding partner Bfa1 act as a GTPase activating protein (GAP) to negatively regulate the MEN ...
Park Su Young +4 more
doaj +1 more source
UCS protein Rng3p is essential for myosin-II motor activity during cytokinesis in fission yeast. [PDF]
PLoS ONE, 2013 UCS proteins have been proposed to operate as co-chaperones that work with Hsp90 in the de novo folding of myosin motors. The fission yeast UCS protein Rng3p is essential for actomyosin ring assembly and cytokinesis.
Benjamin C Stark +4 more
doaj +1 more source