Results 101 to 110 of about 726,631 (184)

The Aspergillus nidulans IQGAP orthologue SepG is required for constriction of the contractile actomyosin ring

Fungal Genetics and Biology, 2020
In this research we report that the sepG1 mutation in Aspergillus nidulans resides in gene AN9463, which is predicted to encode an IQGAP orthologue. The genetic lesion is predicted to result in a G-to-R substitution at residue 1637 of the 1737-residue protein in a highly conserved region of the RasGAP-C-terminal (RGCT) domain. When grown at restrictive
Terry W, Hill, Kristen E, Wendt, David A, Jones, McLean H, Williamson, Uchenna J, Ugwu, Lauren B, Rowland, Loretta, Jackson-Hayes   +6 more
openaire   +3 more sources

The Mechanosensitive Pkd2 Channel Modulates the Recruitment of Myosin II and Actin to the Cytokinetic Contractile Ring

Journal of Fungi
Cytokinesis, the last step in cell division, separates daughter cells through mechanical force. This is often through the force produced by an actomyosin contractile ring.
Pritha Chowdhury, Debatrayee Sinha, Abhishek Poddar, Madhurya Chetluru, Qian Chen   +4 more
doaj   +1 more source

Three types of actomyosin rings within a common cytoplasm exhibit distinct modes of contractility. [PDF]

Mol Biol Cell
Actomyosin rings are specializations of the nonmuscle actomyosin cytoskeleton that drive cell shape changes during division, wound healing, and other events.
Linehan JB, Zampetaki A, Werner ME, Heck B, Maddox PS, Fürthauer S, Maddox AS.   +6 more
europepmc   +2 more sources

A proteomic investigation of forebrain regeneration in the leopard gecko (Eublepharis macularius)

Developmental Dynamics, EarlyView.
Our investigation reveals ontogenetic, injury‐ and regeneration‐associated proteomic changes in the leopard gecko forebrain. Abstract Background The ability to replace lost or damaged neurons following an injury is termed reactive neurogenesis. Although reactive neurogenesis has been reported in several lizard species, the molecular mechanisms ...
Alexandra I. Noble, Samantha L. Payne, Matthew K. Vickaryous   +2 more
wiley   +1 more source

Two Septin complexes mediate actin dynamics during cell wound repair

Cell Reports
Summary: Cells have robust wound repair systems to prevent further damage or infection and to quickly restore cell cortex integrity when exposed to mechanical and chemical stress.
Viktor Stjepić, Mitsutoshi Nakamura, Justin Hui, Susan M. Parkhurst   +3 more
doaj   +1 more source

Rheological and Mechanical Assessment of Injectable Hydrogels: A Framework for Structure–Property Analysis

Polymer Engineering &Science, EarlyView.
A rheological and mechanical assessment framework to construct structure‐property‐application relationships for injectable hydrogels. ABSTRACT Injectable hydrogels have attracted massive research attention thanks to their potential biomedical applications.
Hai Xin, D. S. Abdullah Al Maruf, Boyang Wan   +2 more
wiley   +1 more source

Four‐dimensional immuno‐mechanobiomaterials: Dynamic material cues that program host response to prevent fibrosis and enable regeneration

VIEW, EarlyView.
Dynamic immuno‐mechanobiomaterials with time‐programmed mechanical adaptation orchestrate host responses through precise mechanotransduction and immune‐stromal regulation. These adaptive biomaterials minimize mechanical mismatch, attenuate the forign dy response and fibrosis, promote angiogenesis and controlled extracellular matrix remodeling, and ...
Gobinath Vellapalayam Manoharan, Kathirvel Ayyaswamy, Parthasarathy Vellaichamy, Nagarajan Deivanayagam Pillai, Rithik Gobinath   +4 more
wiley   +1 more source

Recruitment of the mitotic exit network to yeast centrosomes couples septin displacement to actomyosin constriction

Nature Communications, 2018
The Mitotic Exit Network (MEN) promotes mitotic exit and cytokinesis but if and how MEN independently controls these two processes is unclear. Here, the authors report that MEN displaces septins from the cell division site to promote actomyosin ring ...
Davide Tamborrini, Maria Angeles Juanes, Sandy Ibanes, Giulia Rancati, Simonetta Piatti   +4 more
doaj   +1 more source

Cdk1-dependent phosphorylation of Iqg1 governs actomyosin ring assembly prior to cytokinesis. [PDF]

J Cell Sci, 2014
Contraction of the actomyosin ring (AMR) provides the centripetal force that drives cytokinesis. In budding yeast, assembly and contraction of the AMR is coordinated with membrane deposition and septum formation at the bud neck. A central player in this process is Iqg1, which promotes recruitment of actin to the myosin ring and links AMR assembly with ...
Naylor SG, Morgan DO.
europepmc   +3 more sources

Correlative X‐ray imaging and fluorescence microscopy in hydrated environments

Journal of Synchrotron Radiation, EarlyView.
We present a combined imaging platform that integrates beamline‐compatible fluorescence microscopy with scanning small‐angle X‐ray scattering to enable sequential multimodal investigations of hydrated cells under near‐native conditions. We apply our method to ordered cytoskeletal structures in different cell types and demonstrate the direct correlation
Mangalika Sinha, Boram Yu, Rita Mendes Da Silva, Ulrike Rölleke, Peter Luley, Malte Tiburcy, Wolfram-Hubertus Zimmermann, Manfred Burghammer, Sarah Köster   +8 more
wiley   +1 more source