Results 101 to 110 of about 6,880 (162)
The Journal of Physiology, EarlyView.Abstract figure legend Diet‐induced obesity induced fibro‐adipogenic remodelling of the muscle–tendon unit, characterized by increased fibrosis, reduced specific force, impaired relaxation kinetics, elevated hysteresis, and reduced aerobic capacity and glucose tolerance.
Leonardo Cesanelli +9 more
wiley +1 more source
Multidimensional Cellular Micro‐Compartments to Model Invasive Lobular Carcinoma Dormancy
Advanced Healthcare Materials, Volume 15, Issue 31, 21 August 2026.Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that is susceptible to late recurrences. In this study, micro‐compartmentalization techniques spanning multiple dimensions, including 2D, pseudo‐3D, and 3D, are integrated to uncover the mechanisms underlying ILC dormancy, revealing the central role of p27Kip1.
Xilal Y. Rima +15 more
wiley +1 more source
Advanced Science, Volume 13, Issue 45, 13 August 2026.Mechanical intelligence reframes bone regeneration as a time‐dependent coupling between material and cellular memory. Biomaterials store and release mechanical history, while cells retain prior cues and remodel the repair niche. Matching these memories to healing stages may guide stage‐specific scaffolds, sensing‐assisted prediction, mechanical dosing,
Jin Tian +8 more
wiley +1 more source
eLife, 2018 To ensure timely cytokinesis, the equatorial actomyosin contractile ring constricts at a relatively constant rate despite its progressively decreasing size. Thus, the per-unit-length constriction rate increases as ring perimeter decreases.
Renat N Khaliullin +6 more
doaj +1 more source
PP2A-Cdc55 phosphatase regulates actomyosin ring contraction and septum formation during cytokinesis. [PDF]
Cell Mol Life Sci, 2022 Moyano-Rodríguez Y +5 more
europepmc +1 more source
Cell Biochemistry and Function, Volume 44, Issue 8, August 2026.ABSTRACT Adipocyte hypertrophy poses an important mechanical challenge—adipocytes can increase in volume up to a thousand‐fold while still maintaining their structural integrity. Although lipid metabolism is well studied, little is known about the cytoskeletal adaptations that are required to accommodate this expansion and the resulting pathological ...
Dhakshmi Sasankan, Renu Mohan
wiley +1 more source
Clinical and Experimental Dental Research, Volume 12, Issue 4, August 2026.ABSTRACT Objectives Oral squamous cell carcinoma (OSCC) is an aggressive malignancy with few reliable early diagnostic markers. Bioinformatic screening identified hsa_circ_0100833 as a differentially expressed circRNA in OSCC. Its potential significance in OSCC was then examined experimentally.
Behnaz Raei +4 more
wiley +1 more source
Phosphorylation of the F-BAR protein Hof1 drives septin ring splitting in budding yeast
Nature CommunicationsA double septin ring accompanies cytokinesis in yeasts and mammalian cells. In budding yeast, reorganisation of the septin collar at the bud neck into a dynamic double ring is essential for actomyosin ring constriction and cytokinesis.
Maritzaida Varela Salgado +8 more
doaj +1 more source
Making the Final Cut — Mechanisms Mediating the Abscission Step of Cytokinesis
The Scientific World Journal, 2010 Cytokinesis is the final stage of mitotic cell division that results in a physical separation of two daughter cells. Cytokinesis begins in the early stages of anaphase after the positioning of the cleavage plane and after the chromosomes segregate.
John A. Schiel, Rytis Prekeris
doaj +1 more source
Dynamics of actin polymerisation during the mammalian single-cell wound healing response
BMC Research Notes, 2019 Objective The contribution of actomyosin contractile rings in the wound healing program of somatic cells as never been directly assessed. This contrast with the events characterising the wound healing response of in wounded Xenopus oocytes, in which ...
Corina DeKraker +3 more
doaj +1 more source