Results 121 to 130 of about 726,631 (184)
The Journal of Physiology, EarlyView.Abstract figure legend Beat‐locked mitochondrial ATP transients reveal modular, sex‐specific bioenergetic control during excitation–contraction coupling. A, each action potential activates L‐type CaV1.2 channels, producing a Ca2+ influx that triggers ryanodine receptors (RyR2) and elicits SR Ca2+ release.
Paula Rhana +2 more
wiley +1 more source
Dynamics of actin polymerisation during the mammalian single-cell wound healing response
BMC Research Notes, 2019 Objective The contribution of actomyosin contractile rings in the wound healing program of somatic cells as never been directly assessed. This contrast with the events characterising the wound healing response of in wounded Xenopus oocytes, in which ...
Corina DeKraker +3 more
doaj +1 more source
Time-varying mobility and turnover of actomyosin ring components during cytokinesis in Schizosaccharomyces pombe. [PDF]
Mol Biol Cell, 2021 Kamnev A +5 more
europepmc +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Diet‐induced obesity induced fibro‐adipogenic remodelling of the muscle–tendon unit, characterized by increased fibrosis, reduced specific force, impaired relaxation kinetics, elevated hysteresis, and reduced aerobic capacity and glucose tolerance.
Leonardo Cesanelli +9 more
wiley +1 more source
Journal of the Royal Society of New Zealand, Volume 57, Issue 1, February 2027.This review examines the current literature on the application of atomic force microscopy (AFM) to cancer mechanophenotyping, with particular emphasis on cellular Young's modulus and its potential diagnostic significance. A structured electronic search of PubMed, Scopus and Google Scholar was conducted to identify studies published between 1999 and ...
Hermawan Tjoa +4 more
wiley +1 more source
Molecular Oncology, Volume 20, Issue 11, Page 2674-2698, November 2026.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Annals of Gastroenterological Surgery, Volume 10, Issue 6, Page 1691-1698, November 2026.ABSTRACT Scirrhous gastric cancer, characterized by diffuse infiltration and a high propensity for peritoneal dissemination, remains one of the most aggressive subtypes of gastric cancer. Despite a relatively high incidence of splenic hilar lymph node (No. 10) metastasis, the oncologic benefit of splenectomy remains controversial, while its association
Tsutomu Hayashi, Takaki Yoshikawa
wiley +1 more source
Septin clearance from the division site triggers cytokinesis in budding yeast
Microbial Cell, 2019 In many eukaryotic cells cytokinesis involves a contractile actomyosin ring (CAR) that drives cleavage furrow ingression. What triggers CAR constriction at a precise time of the cell cycle and how constriction is coupled to chromosome segregation are ...
Davide Tamborrini, Simonetta Piatti
doaj +1 more source
Food Frontiers, Volume 7, Issue 6, November 2026.ABSTRACT Epilepsy is the most disabling neurological disease that affects all economic classes, age groups, regions, and races. Although many antiseizure drugs are approved for epilepsy treatment, they fail to work in about 30%–40% of patients. Thus, there is a great need to identify better pharmacological agents to treat epilepsy.
Janakiraman Pillai Udaiyappan +3 more
wiley +1 more source
Genes to Cells, Volume 31, Issue 6, November 2026.Changes in cell geometry caused by increased cell density, F‐actin disruption, or trypsinization promote nuclear rounding and nuclear wrinkle (NW) formation. NWs arise through passive redistribution of excess nuclear surface area and are reversible, without detectable DNA damage, stress‐associated histone H3 Ser10 phosphorylation, or global nuclear ...
Le Minh Khoa +3 more
wiley +1 more source