Results 91 to 100 of about 6,880 (162)

The Aspergillus nidulans IQGAP orthologue SepG is required for constriction of the contractile actomyosin ring

open access: yesFungal Genetics and Biology, 2020
In this research we report that the sepG1 mutation in Aspergillus nidulans resides in gene AN9463, which is predicted to encode an IQGAP orthologue. The genetic lesion is predicted to result in a G-to-R substitution at residue 1637 of the 1737-residue protein in a highly conserved region of the RasGAP-C-terminal (RGCT) domain. When grown at restrictive
Terry W, Hill   +6 more
openaire   +3 more sources

Network Contractility during Cytokinesis—From Molecular to Global Views

open access: yesBiomolecules, 2019
Cytokinesis is the last stage of cell division, which partitions the mother cell into two daughter cells. It requires the assembly and constriction of a contractile ring that consists of a filamentous contractile network of actin and myosin.
Joana Leite   +4 more
doaj   +1 more source

The preprophase band is dispensable for robust cell division orientation in wood‐forming cambium stem cells

open access: yesNew Phytologist, EarlyView.
Characterization of periclinal and anticlinal cell divisions in dividing cambium stem cells (CSCs). (a) Scheme indicating periclinal and anticlinal cell divisions in CSCs in the Arabidopsis hypocotyl. The orange dashed ring in the middle panel represents the cambium area. The orange cuboids represent individual CSCs.
Xiaomin Liu   +4 more
wiley   +1 more source

Assembly of normal actomyosin rings in the absence of Mid1p and cortical nodes in fission yeast [PDF]

open access: yesThe Journal of Cell Biology, 2008
Cytokinesis in many eukaryotes depends on the function of an actomyosin contractile ring. The mechanisms regulating assembly and positioning of this ring are not fully understood. The fission yeast Schizosaccharomyces pombe divides using an actomyosin ring and is an attractive organism for the study of cytokinesis. Recent studies in S. pombe (Wu, J.Q.,
Huang, Yinyi   +2 more
openaire   +2 more sources

The Mechanosensitive Pkd2 Channel Modulates the Recruitment of Myosin II and Actin to the Cytokinetic Contractile Ring

open access: yesJournal of Fungi
Cytokinesis, the last step in cell division, separates daughter cells through mechanical force. This is often through the force produced by an actomyosin contractile ring.
Pritha Chowdhury   +4 more
doaj   +1 more source

Two Septin complexes mediate actin dynamics during cell wound repair

open access: yesCell Reports
Summary: Cells have robust wound repair systems to prevent further damage or infection and to quickly restore cell cortex integrity when exposed to mechanical and chemical stress.
Viktor Stjepić   +3 more
doaj   +1 more source

Calcium‐activated chloride channels in pericytes and their role in regulating organ blood flow

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Pericytes are microvascular mural cells with diverse roles. Contractile pericytes directly regulate local perfusion, while non‐contractile pericytes coordinate upstream vascular contractility via propagating electrical signals.
Paolo Tammaro, Hikaru Hashitani
wiley   +1 more source

Recruitment of the mitotic exit network to yeast centrosomes couples septin displacement to actomyosin constriction

open access: yesNature Communications, 2018
The Mitotic Exit Network (MEN) promotes mitotic exit and cytokinesis but if and how MEN independently controls these two processes is unclear. Here, the authors report that MEN displaces septins from the cell division site to promote actomyosin ring ...
Davide Tamborrini   +4 more
doaj   +1 more source

Demonstration of beat‐to‐beat, on‐demand ATP synthesis in ventricular myocytes reveals sex‐specific mitochondrial and cytosolic dynamics

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Beat‐locked mitochondrial ATP transients reveal modular, sex‐specific bioenergetic control during excitation–contraction coupling. A, each action potential activates L‐type CaV1.2 channels, producing a Ca2+ influx that triggers ryanodine receptors (RyR2) and elicits SR Ca2+ release.
Paula Rhana   +2 more
wiley   +1 more source

Old dog, new trick: Charybdotoxin as a novel ryanodine receptor blocker

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend The peptide toxin charybdotoxin (ChTx) from the scorpion Leiurus quinquestriatus was tested on single‐channel currents of the ryanodine receptor incorporated into planar lipid bilayers. The structure–function relationship of ChTx was investigated using toxin variants generated by isosteric substitutions of the basic amino acids ...
Zsuzsanna Édua Magyar   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy