Results 91 to 100 of about 726,631 (184)
Identification of Yeast IQGAP (Iqg1p) as an Anaphase-Promoting-Complex Substrate and Its Role in Actomyosin-Ring-Independent Cytokinesis [PDF]
, 2007 In the yeast Saccharomyces cerevisiae, a ring of myosin II forms in a septin-dependent manner at the budding site in late G1. This ring remains at the bud neck until the onset of cytokinesis, when actin is recruited to it.
John R. Pringle +13 more
core +1 more source
The Kinesin Speed Paradox Revisited: How Can Cargoes Move Faster Than Their Motors?
Cytoskeleton, EarlyView.ABSTRACT Intracellular transport is essential for cellular organization and function. Kinesin‐1, the founding member of the kinesin superfamily, delivers a wide range of cargoes along microtubules. Since its discovery, extensive work has identified cargo–kinesin interactions and regulatory mechanisms.
Kanako Iwasaki, Yasushi Okada
wiley +1 more source
Curvature-induced expulsion of actomyosin bundles during cytokinetic ring contraction
, 2020 Many eukaryotes assemble a ring-shaped actomyosin network that contracts to drive cytokinesis. Unlike actomyosin in sarcomeres, which cycles through contraction and relaxation, the cytokinetic ring disassembles during contraction through an unknown ...
Ying Gu +11 more
core
The Anaphase-promoting Complex Promotes Actomyosin-Ring Disassembly during Cytokinesis in Yeast [PDF]
Molecular Biology of the Cell, 2009 The anaphase-promoting complex (APC) is a ubiquitin ligase that controls progression through mitosis by targeting specific proteins for degradation. It is unclear whether the APC also contributes to the control of cytokinesis, the process that divides the cell after mitosis.
Gregory H, Tully +3 more
openaire +2 more sources
Actin depolymerization drives actomyosin ring contraction during budding yeast cytokinesis. [PDF]
Dev Cell, 2012 Actin filaments and myosin II are evolutionarily conserved force-generating components of the contractile ring during cytokinesis. Here we show that in budding yeast, actin filament depolymerization plays a major role in actomyosin ring constriction.
Mendes Pinto I +4 more
europepmc +4 more sources
Cytoskeleton, EarlyView.ABSTRACT Actin filaments exhibit isoform and species‐specific mechanical properties that are commonly quantified via their persistence length, yet the reliability of such measurements depends not only on the analysis method but also on dataset characteristics.
Peter Nietmann +3 more
wiley +1 more source
, 2002 Schizosaccharomyces pombe cells divide by medial fission through the use of an actomyosin-based contractile ring. Constriction of the actomyosin ring is accompanied by the centripetal addition of new membranes and cell wall material.
Liu, Jianhua +4 more
core +1 more source
Network Contractility during Cytokinesis—From Molecular to Global Views
Biomolecules, 2019 Cytokinesis is the last stage of cell division, which partitions the mother cell into two daughter cells. It requires the assembly and constriction of a contractile ring that consists of a filamentous contractile network of actin and myosin.
Joana Leite +4 more
doaj +1 more source
Cytoskeleton, EarlyView.ABSTRACT We here describe mouse models with complementary homozygous Svil mutations. In skeletal muscle, Svil‐Mut mice express the Svil‐encoded N‐terminus fused to the βgal‐neo gene‐trap tag and lack the highly conserved archvillin C‐terminus; Svil‐KO mice lack expression of all known Svil‐encoded proteins; and Svil‐LoxP mice contain loxP sites for ...
Tara C. Smith +9 more
wiley +1 more source
Structure of the fission yeast actomyosin ring during constriction
, 2017 Cell division in many eukaryotes is driven by a ring containing actin and myosin. While much is known about the main proteins involved, the precise arrangement of actin filaments within the contractile machinery, and how force is transmitted to the ...
Davi R. Ortega +6 more
core +1 more source