Results 51 to 60 of about 6,880 (162)

Septum development in Neurospora crassa: the septal actomyosin tangle. [PDF]

open access: yesPLoS ONE, 2014
Septum formation in Neurospora crassa was studied by fluorescent tagging of actin, myosin, tropomyosin, formin, fimbrin, BUD-4, and CHS-1. In chronological order, we recognized three septum development stages: 1) septal actomyosin tangle (SAT) assembly ...
Diego Luis Delgado-Álvarez   +3 more
doaj   +1 more source

Fission yeast septation

open access: yesCommunicative & Integrative Biology, 2016
In animal cells cytokinesis relies on the contraction of an actomyosin ring that pulls the plasma membrane to create a cleavage furrow, whose ingression finally divides the mother cell into two daughter cells.
Juan C. G. Cortés   +4 more
doaj   +1 more source

The integrity of the cytokinesis machinery under stress conditions requires the glucan synthase Bgs1p and its regulator Cfh3p. [PDF]

open access: yesPLoS ONE, 2012
In yeast, cytokinesis requires coordination between nuclear division, acto-myosin ring contraction, and septum synthesis. We studied the role of the Schizosaccharomyces pombe Bgs1p and Cfh3p proteins during cytokinesis under stress conditions.
Mohammad Reza Sharifmoghadam   +6 more
doaj   +1 more source

TOR complex 2 localises to the cytokinetic actomyosin ring and controls the fidelity of cytokinesis. [PDF]

open access: yesJ Cell Sci, 2016
ABSTRACT The timing of cell division is controlled by the coupled regulation of growth and division. The target of rapamycin (TOR) signalling network synchronises these processes with the environmental setting. Here, we describe a novel interaction of the fission yeast TOR complex 2 (TORC2) with the cytokinetic actomyosin ring (CAR), and
Baker K   +9 more
europepmc   +4 more sources

An equatorial contractile mechanism drives cell elongation but not cell division.

open access: yesPLoS Biology, 2014
Cell shape changes and proliferation are two fundamental strategies for morphogenesis in animal development. During embryogenesis of the simple chordate Ciona intestinalis, elongation of individual notochord cells constitutes a crucial stage of notochord
Ivonne M Sehring   +6 more
doaj   +1 more source

Nuc2p, a subunit of the anaphase-promoting complex, inhibits septation initiation network following cytokinesis in fission yeast. [PDF]

open access: yesPLoS Genetics, 2008
In most cell types, mitosis and cytokinesis are tightly coupled such that cytokinesis occurs only once per cell cycle. The fission yeast Schizosaccharomyces pombe divides using an actomyosin-based contractile ring and is an attractive model for the study
Ting Gang Chew, Mohan K Balasubramanian
doaj   +1 more source

Radial contractility of actomyosin rings facilitates axonal trafficking and structural stability

open access: yesJournal of Cell Biology, 2020
Most mammalian neurons have a narrow axon, which constrains the passage of large cargoes such as autophagosomes that can be larger than the axon diameter. Radial axonal expansion must therefore occur to ensure efficient axonal trafficking. In this study, we reveal that the speed of various large cargoes undergoing axonal transport is significantly ...
Tong Wang   +11 more
openaire   +5 more sources

Swelling‐Programmed Topographical Guidance for Dynamic Spheroid Self‐Assembly via a Mechanochemical Hydrogel Niche

open access: yesAdvanced Functional Materials, EarlyView.
A swelling‐programmed micropatterned hydrogel guides adherent cells through a controlled transition from cell–matrix anchoring to cadherin‐mediated cell–cell compaction, enabling rapid assembly of high‐viability spheroids with defined size and morphology.
Han Gyeol Nam   +8 more
wiley   +1 more source

ER-PM Contacts Define Actomyosin Kinetics for Proper Contractile Ring Assembly [PDF]

open access: yesCurrent Biology, 2016
The cortical endoplasmic reticulum (ER), an elaborate network of tubules and cisternae [1], establishes contact sites with the plasma membrane (PM) through tethering machinery involving a set of conserved integral ER proteins [2]. The physiological consequences of forming ER-PM contacts are not fully understood.
Zhang, Dan   +2 more
openaire   +2 more sources

Cellular Responses to Mechanical Cues Across Scales: From Fundamental Insights to Translational Potential

open access: yesAdvanced Healthcare Materials, EarlyView.
This review examines how cellular behavior is regulated by mechanical cues transmitted through soft biomaterials, from single‐cell mechanosensing to tissue‐level adaptation. It highlights why physiological relevance, rather than model complexity alone, is critical for translational mechanobiology and introduces a scoring framework linking material ...
Mathias Polz   +9 more
wiley   +1 more source

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