Results 31 to 40 of about 726,631 (184)
Reconstitution of contractile actomyosin rings in vesicles [PDF]
Nature Communications, 2020 Abstract One of the grand challenges of bottom-up synthetic biology is the development of minimal machineries for cell division. The mechanical transformation of large-scale compartments, such as Giant Unilamellar Vesicles (GUVs), requires the geometry-specific coordination of active elements, several orders of magnitude larger than ...
Thomas Litschel +8 more
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Bio-Protocol, 2022 Cytokinesis occurs at the final step of cell division and leads to the separation of daughter cells. It requires assembly and constriction of the actomyosin contractile ring.
Swati Sharma, Richa Rikhy
doaj +1 more source
A New Membrane Protein Sbg1 Links the Contractile Ring Apparatus and Septum Synthesis Machinery in Fission Yeast. [PDF]
PLoS Genetics, 2016 Cytokinesis in many organisms requires a plasma membrane anchored actomyosin ring, whose contraction facilitates cell division. In yeast and fungi, actomyosin ring constriction is also coordinated with division septum assembly.
Kriti Sethi +10 more
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Force to divide: structural and mechanical requirements for actomyosin ring contraction. [PDF]
Biophys J, 2013 One of the unresolved questions in the field of cell division is how the actomyosin cytoskeleton remains structurally organized while generating the contractile force to divide one cell into two. In analogy to the actomyosin-based force production mechanism in striated muscle, it was originally proposed that contractile stress in the actomyosin ring is
Mendes Pinto I, Rubinstein B, Li R.
europepmc +4 more sources
Encapsulated actomyosin patterns drive cell-like membrane shape changes
iScience, 2022 Summary: Cell shape changes from locomotion to cytokinesis are, to a large extent, driven by myosin-driven remodeling of cortical actin patterns.
Yashar Bashirzadeh +2 more
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PP1-Dependent Formin Bnr1 Dephosphorylation and Delocalization from a Cell Division Site. [PDF]
PLoS ONE, 2016 Cell cycle ends with cytokinesis that is the physical separation of a cell into two daughter cells. For faithful cytokinesis, cells integrate multiple processes, such as actomyosin ring formation, contraction and plasma membrane closure, into coherent ...
Minami Orii +3 more
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Scar/WAVE has Rac GTPase-independent functions during cell wound repair
Scientific Reports, 2023 Rho family GTPases regulate both linear and branched actin dynamics by activating downstream effectors to facilitate the assembly and function of complex cellular structures such as lamellipodia and contractile actomyosin rings. Wiskott-Aldrich Syndrome (
Mitsutoshi Nakamura +3 more
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Coordinating septum formation and the actomyosin ring during cytokinesis in Schizosaccharomyces pombe. [PDF]
Mol Microbiol, 2019 SummaryDuring cytokinesis, animal and fungal cells form a membrane furrow via actomyosin ring constriction. Our understanding of actomyosin ring‐driven cytokinesis stems extensively from the fission yeast model system. However, unlike animal cells, actomyosin ring constriction occurs simultaneously with septum formation in fungi. While the formation of
Hercyk BS, Onwubiko UN, Das ME.
europepmc +4 more sources
Structure and Constriction Mechanism of the Actomyosin Ring [PDF]
Biophysical Journal, 2018 Cytokinesis is orchestrated by a contractile actomyosin ring, but its structure and mechanism remain elusive. We visualized the 3D structure of the ring in frozen‐hydrated dividing yeast cells by electron cryotomography (ECT). Detailed arrangements of actin filaments within the ring and with respect to the membrane were seen for the first time ...
Nguyen, Lam T. +2 more
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eLife, 2021 Structures and machines require smoothening of raw materials. Self-organized smoothening guides cell and tissue morphogenesis and is relevant to advanced manufacturing.
Medha Sharma +4 more
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