Results 31 to 40 of about 6,880 (162)
Scar/WAVE has Rac GTPase-independent functions during cell wound repair
Scientific Reports, 2023 Rho family GTPases regulate both linear and branched actin dynamics by activating downstream effectors to facilitate the assembly and function of complex cellular structures such as lamellipodia and contractile actomyosin rings. Wiskott-Aldrich Syndrome (
Mitsutoshi Nakamura +3 more
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Stabilization of the Actomyosin Ring Enables Spermatocyte Cytokinesis in Drosophila [PDF]
Molecular Biology of the Cell, 2010 The scaffolding protein anillin is required for completion of cytokinesis. Anillin binds filamentous (F) actin, nonmuscle myosin II, and septins and in cell culture models has been shown to restrict actomyosin contractility to the cleavage furrow. Whether anillin also serves this function during the incomplete cytokinesis that occurs in developing germ
Goldbach, Philip +5 more
openaire +2 more sources
eLife, 2021 Structures and machines require smoothening of raw materials. Self-organized smoothening guides cell and tissue morphogenesis and is relevant to advanced manufacturing.
Medha Sharma +4 more
doaj +1 more source
Involvement of an Actomyosin Contractile Ring in Saccharomyces cerevisiae Cytokinesis [PDF]
The Journal of Cell Biology, 1998 In Saccharomyces cerevisiae, the mother cell and bud are connected by a narrow neck. The mechanism by which this neck is closed during cytokinesis has been unclear. Here we report on the role of a contractile actomyosin ring in this process. Myo1p (the only type II myosin in S.
E, Bi +6 more
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Force Generation and Contraction of Random Actomyosin Rings [PDF]
Biophysical Journal, 2015 Cytokinetic rings and stress fibers generate effective contraction, but how organized respective actomyosin arrays are, and how semi-random actomyosin bundles generate contraction is not clear.We investigate computationally the self-organization and contraction of an actomyosin ring that is completely disorganized initially. To this end, we formulate a
Oelz, Dietmar B. +2 more
openaire +1 more source
The role of the host—Neutrophil biology
Periodontology 2000, EarlyView., 2023 Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple +4 more
wiley +1 more source
MPF governs the assembly and contraction of actomyosin rings by activating RhoA and MAPK during chemical-induced cytokinesis of goat oocytes. [PDF]
PLoS ONE, 2010 The interplay between maturation-promoting factor (MPF), mitogen-activated protein kinase (MAPK) and Rho GTPase during actin-myosin interactions has yet to be determined.
Yan-Guang Wu +7 more
doaj +1 more source
Actomyosin Rings: The Riddle of the Sphincter [PDF]
Current Biology, 2002 Contractile rings consisting of actin filaments and myosin-2 have long been known to power cytokinesis, but recent work has shown that single-cell and multicellular actomyosin rings participate in processes ranging from wound healing to extrusion of apoptotic cells from epithelia.
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Cortical flow aligns actin filaments to form a furrow
eLife, 2016 Cytokinesis in eukaryotic cells is often accompanied by actomyosin cortical flow. Over 30 years ago, Borisy and White proposed that cortical flow converging upon the cell equator compresses the actomyosin network to mechanically align actin filaments ...
Anne-Cecile Reymann +4 more
doaj +1 more source
Cell polarity protein Spa2 coordinates Chs2 incorporation at the division site in budding yeast. [PDF]
PLoS Genetics, 2018 Deposition of additional plasma membrane and cargoes during cytokinesis in eukaryotic cells must be coordinated with actomyosin ring contraction, plasma membrane ingression and extracellular matrix remodelling.
Magdalena Foltman +3 more
doaj +1 more source