Results 11 to 20 of about 57,563 (148)

Loss of a Rho-Regulated Actin Nucleator, mDia2, Impairs Cytokinesis during Mouse Fetal Erythropoiesis

Cell Reports, 2013
The small GTPase Rho and mDia2, a Rho-regulated actin nucleator, function as critical regulators of cytokinesis in cultured cells. However, their involvement in cytokinesis during mammalian development remains unknown.
Sadanori Watanabe, Tihana De Zan, Toshimasa Ishizaki, Shingo Yasuda, Hiroshi Kamijo, Daisuke Yamada, Tomohiro Aoki, Hiroshi Kiyonari, Hiroshi Kaneko, Ritsuko Shimizu, Masayuki Yamamoto, Gohta Goshima, Shuh Narumiya   +12 more
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Functional Analyses of Cytokinesis Regulators in Bloodstream Stage Trypanosoma brucei Parasites Identify Functions and Regulations Specific to the Life Cycle Stage

mSphere, 2019
The early divergent protozoan parasite Trypanosoma brucei alternates between the insect vector and the mammalian hosts during its life cycle and proliferates through binary cell fission. The cell cycle control system in T.
Xuan Zhang, Tai An, Kieu T. M. Pham, Zhao-Rong Lun, Ziyin Li   +4 more
doaj   +1 more source

Comprehensive analysis of the human ESCRT-III-MIT domain interactome reveals new cofactors for cytokinetic abscission

eLife, 2022
The 12 related human ESCRT-III proteins form filaments that constrict membranes and mediate fission, including during cytokinetic abscission. The C-terminal tails of polymerized ESCRT-III subunits also bind proteins that contain Microtubule-Interacting ...
Dawn M Wenzel, Douglas R Mackay, Jack J Skalicky, Elliott L Paine, Matthew S Miller, Katharine S Ullman, Wesley I Sundquist   +6 more
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Septin Remodeling During Mammalian Cytokinesis

Frontiers in Cell and Developmental Biology, 2021
Cytokinesis mediates the final separation of a mother cell into two daughter cells. Septins are recruited to the cleavage furrow at an early stage. During cytokinetic progression the septin cytoskeleton is constantly rearranged, ultimately leading to a ...
Giulia Russo, Michael Krauss
doaj   +1 more source

Extracellular Vesicles of Human Periodontal Ligament Stem Cells Contain MicroRNAs Associated to Proto-Oncogenes: Implications in Cytokinesis

Frontiers in Genetics, 2020
The human Periodontal Ligament Stem Cells (hPDLSCs) exhibit self-renewal capacity and clonogenicity potential. The Extracellular Vesicles (EVs) secreted by hPDLSCs are particles containing lipids, proteins, mRNAs, and non-coding RNAs, among which ...
Luigi Chiricosta, Serena Silvestro, Agnese Gugliandolo, Guya Diletta Marconi, Jacopo Pizzicannella, Placido Bramanti, Oriana Trubiani, Emanuela Mazzon   +7 more
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Regulation of the Total Cell Surface Area in Dividing Dictyostelium Cells

Frontiers in Cell and Developmental Biology, 2020
When a cell divides into two daughter cells, the total cell surface area should increase. There are two models for membrane supply to support cell division: (1) unfolding of small surface membrane reservoirs such as microvilli or wrinkles and (2 ...
Masahito Tanaka, Koushiro Fujimoto, Shigehiko Yumura   +2 more
doaj   +1 more source

The MERS-CoV N Protein Regulates Host Cytokinesis and Protein Translation via Interaction With EF1A

Frontiers in Microbiology, 2021
Middle East respiratory syndrome coronavirus (MERS-CoV), a pathogen causing severe respiratory disease in humans that emerged in June 2012, is a novel beta coronavirus similar to severe acute respiratory syndrome coronavirus (SARS-CoV).
Lin Zhu, Lin Zhu, Ting Gao, Yangbo Fu, Xiujing Han, Junjie Yue, Yaoning Liu, Hainan Liu, Qincai Dong, Weihong Yang, Yong Hu, Yanwen Jin, Ping Li, Xuan Liu, Cheng Cao   +14 more
doaj   +1 more source

Anillin Phosphorylation Controls Timely Membrane Association and Successful Cytokinesis.

PLoS Genetics, 2017
During cytokinesis, a contractile ring generates the constricting force to divide a cell into two daughters. This ring is composed of filamentous actin and the motor protein myosin, along with additional structural and regulatory proteins, including ...
Hyunjung Kim, James M Johnson, Robert F Lera, Sarang Brahma, Mark E Burkard   +4 more
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Matrix compliance and the regulation of cytokinesis

Biology Open, 2015
Integrin-mediated cell adhesion to the ECM regulates many physiological processes in part by controlling cell proliferation. It is well established that many normal cells require integrin-mediated adhesion to enter S phase of the cell cycle.
Savitha Sambandamoorthy, Shomita Mathew-Steiner, Scott Varney, Jonathan M. Zuidema, Ryan J. Gilbert, Livingston Van De Water, Susan E. LaFlamme   +6 more
doaj   +1 more source

The Role of the Cell Integrity Pathway in Septum Assembly in Yeast

Journal of Fungi, 2021
Cytokinesis divides a mother cell into two daughter cells at the end of each cell cycle and proceeds via the assembly and constriction of a contractile actomyosin ring (CAR).
Cesar Roncero, Rubén Celador, Noelia Sánchez, Patricia García, Yolanda Sánchez   +4 more
doaj   +1 more source