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Cytokinesis is the final stage of cell division during which the two daughter cells separate completely. Although less well understood than some of the earlier phases of the cell cycle, recent discoveries have shed light on the mechanisms that orchestrate this process, including cleavage furrow formation, midbody maturation and abscission.
Sagona, Antonia P., Stenmark, Harald
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Regulation of the Total Cell Surface Area in Dividing Dictyostelium Cells
When a cell divides into two daughter cells, the total cell surface area should increase. There are two models for membrane supply to support cell division: (1) unfolding of small surface membrane reservoirs such as microvilli or wrinkles and (2 ...
Masahito Tanaka +2 more
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The MERS-CoV N Protein Regulates Host Cytokinesis and Protein Translation via Interaction With EF1A
Middle East respiratory syndrome coronavirus (MERS-CoV), a pathogen causing severe respiratory disease in humans that emerged in June 2012, is a novel beta coronavirus similar to severe acute respiratory syndrome coronavirus (SARS-CoV).
Lin Zhu +14 more
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Anillin Phosphorylation Controls Timely Membrane Association and Successful Cytokinesis.
During cytokinesis, a contractile ring generates the constricting force to divide a cell into two daughters. This ring is composed of filamentous actin and the motor protein myosin, along with additional structural and regulatory proteins, including ...
Hyunjung Kim +4 more
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The Role of the Cell Integrity Pathway in Septum Assembly in Yeast
Cytokinesis divides a mother cell into two daughter cells at the end of each cell cycle and proceeds via the assembly and constriction of a contractile actomyosin ring (CAR).
Cesar Roncero +4 more
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Cytokinesis and the Spindle Midzone [PDF]
At the end of the cell cycle a cell physically divides into two daughter cells in a process called cytokinesis. Cytokinesis consists of at least four steps: (1) The position of the presumptive cytokinesis furrow is specified. (2) A contractile ring is formed. (3) The contractile ring contracts, resulting in furrow ingression.
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A novel mode of cytokinesis without cell-substratum adhesion
Cytokinesis is a final step in cell division. Dictyostelium cells, a model organism for the study of cytokinesis, have multiple modes, denoted cytokinesis A, B, C, and D.
Risa Taira, Shigehiko Yumura
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Matrix compliance and the regulation of cytokinesis
Integrin-mediated cell adhesion to the ECM regulates many physiological processes in part by controlling cell proliferation. It is well established that many normal cells require integrin-mediated adhesion to enter S phase of the cell cycle.
Savitha Sambandamoorthy +6 more
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Yorkie and JNK Control Tumorigenesis in Drosophila Cells with Cytokinesis Failure
Summary: Cytokinesis failure may result in the formation of polyploid cells, and subsequent mitosis can lead to aneuploidy and tumor formation. Tumor suppressor mechanisms limiting the oncogenic potential of these cells have been described.
Stephan U. Gerlach +2 more
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Cytokinesis, or the division of the cytoplasm, following the end of mitosis or meiosis, is accomplished in animal cells, fungi, and amoebae, by the constriction of an actomyosin contractile ring, comprising filamentous actin, myosin II, and associated ...
Tansy C. Hammarton
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