Results 191 to 200 of about 143,380 (285)

Partitioning endosomes [PDF]

The Journal of Cell Biology, 2006
openaire   +1 more source

Aliphatic Poly(Carbonate)s with Acid Responsive Release Mechanisms for Micellar Anti‐Tumor Drug Delivery

Macromolecular Rapid Communications, EarlyView.
Micellar systems based on biodegradable aliphatic polycarbonates and acid‐responsive triggers enhance drug solubility, stability, and tumor‐selective release. This review covers micelles with acid‐cleavable drug linkages and those that disassemble via acid‐sensitive functionalities.
Adrian V. Hauck, Lutz Nuhn
wiley   +1 more source

Staufen dsRNA-binding domain as modules to design bifunctional antibodies for siRNA delivery. [PDF]

Nucleic Acids Res
Liu Y, Zheng Y, Xu R, Quan Y, Tai W.
europepmc   +1 more source

VPS13A Deficiency Leads to Impaired Lipid Distribution and Alteration of Mitochondrial Calcium Homeostasis in Fibroblasts of VPS13A Disease Patients

Movement Disorders, EarlyView.
Abstract Background Membrane contact sites are crucial for the exchange of ions or lipids and thus are critical for the function and maintenance of organelles. VPS13A is a membrane‐residing, bridge‐like protein connecting two membranes to enable bulk lipid transfer. Loss‐of‐function mutations in the VPS13A gene cause VPS13A disease.
Dajana Grossmann, Adrian Spranger, Emily Fischer, Johanna W. Schubarth, Jenny Leopold, Hannes Glaß, Sebastian Klicker, My Uyen Dang Thi, Anna Elisabeth Bartalis, Andreas Hermann, Kevin Peikert   +10 more
wiley   +1 more source

NoxO1 promotes endosome formation and reduces intracellular vesicle processing. [PDF]

Redox Biol
Hebchen M, Herwig F, Schader T, Spaeth M, Müller N, Schröder K.   +5 more
europepmc   +1 more source

Migrasomes, Matrix‐Bound Nanovesicles, and More: Messengers in the Matrix

PROTEOMICS, EarlyView.
ABSTRACT Extracellular vesicles (EVs) and particles (EPs) are diverse micro‐ and nanoparticles that circulate in bodily fluids and can attach to, or be deposited onto, the extracellular matrix (ECM) and other surfaces. To date, the nomenclature and classification of matrix‐bound or matrix‐associated EVs and EPs (MEVPs) have been unclear, largely due to
Anna V. Kolesov, Natalie Reitz, Marley Dewey, Colin L. Hisey   +3 more
wiley   +1 more source

Vesicle-coupled mRNA transport and translation govern intracellular organelle networking. [PDF]

EMBO Rep
Vázquez-Carrada M, Shanmugasundaram S, Smits SHJ, van Wijlick L, Feldbrügge M.   +4 more
europepmc   +1 more source

Reduction in Synaptic Vesicle Protein Abundance but Increased Amounts of Nsg2 and Lpcat1 in Cerebral Cortices Without the Endosomal SNARE Proteins Vti1a and Vti1b

PROTEOMICS, EarlyView.
ABSTRACT Absence of the endosomal SNAREs vti1a and vti1b results in perinatal death and severe neuronal phenotypes in mice, while lack of one of these proteins results in minor phenotypes. Proteomic differences were investigated to obtain a deeper insight into processes in which vti1a and vti1b are involved.
Julia Gottschalk, Katharina Kotschnew, Julia Hahn, Thomas Patschkowski, Gabriele von Fischer von Mollard   +4 more
wiley   +1 more source

Microvillus inclusion disease-associated MYO5B deficiency impairs endosome-to-mitochondrion iron transfer. [PDF]

Gastroenterol Rep (Oxf)
Sun C, Leng C, Sun M, Lin Y, Xu M, Martinez-Barriocanal Á, Gerding A, Kuipers J, de Leeuw J, Bakker BM, Arango D, van IJzendoorn SCD.   +11 more
europepmc   +1 more source

Heavy Metals in Elecronic Cigarette Aersol Can Accumulate in Lung Epithelial Cells [PDF]

, 2019
Zaman, Rafay
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