Results 161 to 170 of about 113,399 (298)

pH‐Driven Actuation of Unmodified DNA Origami Rectangles

Angewandte Chemie, EarlyView.
Unmodified DNA origami rectangles exhibit a reversible transition between planar and tubular states driven by near‐neutral pH changes. This behavior arises from crossover‐mediated mechanical coupling of overwound DNA and extends to dimers and nanoribbons, enabling the formation of nanotube architectures without added motifs or chemical modification ...
Diego A. Uehara, Yasmin H. Khazid, Willi R. Berg, Veronika Valova, Felix J. Rizzuto   +4 more
wiley   +2 more sources

Induction of Methuosis in Breast Cancer Stem Cells by a Cobalt(III) Complex Evokes Immunotherapeutic Response

Angewandte Chemie, EarlyView.
Cancer stem cells (CSCs) drive metastasis, relapse and resist conventional apoptosis‐inducing chemotherapies. We report a cobalt(III)‐cyclam complex with pyrene and diflunisal moieties that reduces the viability of breast CSCs at low micromolar concentrations.
Jiaxin Fang, Sijie Wen, Xiao Feng, Hao Ren, Kuldip Singh, Haihua Xiao, Lingpu Zhang, Kogularamanan Suntharalingam   +7 more
wiley   +2 more sources

Extending the ATP9A‐Related Phenotypic Spectrum: Indication of Schizophrenia Susceptibility

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT ATP9A, which belongs to the P4‐ATPase family of proteins, is involved in the efficient transport of vesicles from the Golgi apparatus to the plasma membrane, as well as the release of extracellular vesicles from human cells. In 2021, a loss‐of‐function variant of this gene was identified as being associated with a recessive neurodevelopmental ...
Camille Verebi, Céline Louveau, Bertrand Diebold, Natacha Gaitch, Arnaud Hubas, Martine Gautier Vallee, Jérôme Champ, Anais L'Haridon, Sophie Georgin Lavialle, Boris Chaumette, Thierry Bienvenu   +10 more
wiley   +1 more source

Biophysical Characterization and Proteomic Analysis of Small Extracellular Vesicles Derived From Different Neural Cell Lines

Advanced NanoBiomed Research, EarlyView.
This study systematically compares small extracellular vesicles (sEVs) derived from four neural cell lines, revealing how cellular origin shapes vesicle biophysical properties and proteomic cargo. Distinct, lineage‐specific signatures linked to neuronal, astrocytic, and microglial functions are identified, highlighting the importance of cell source ...
Muhammad Waqas Salim, Wei Zhang, Lyndsey E. Collins‐Praino, Andrew Care, Yuling Wang   +4 more
wiley   +1 more source

The <i>C. elegans</i> WASH complex supports epithelial polarity by promoting endosomal sorting of E-Cadherin. [PDF]

Mol Biol Cell
Irizarry-Barreto P, Smolyn J, Brown V, Ramamurthy B, Soto MC.   +4 more
europepmc   +1 more source

pH‐Responsive Ultrasmall Iron Oxide Nanoassemblies for Activatable T2/T1 Magnetic Resonance Imaging

Advanced NanoBiomed Research, EarlyView.
This research reports a pH‐responsive ultrasmall iron oxide nanoparticle (USIONs)/polymer nanoassemblies for activatable magnetic resonance imaging. Amphiphilic diphosphonic acid block copolymers compactly encapsulate USIONs to generate T2‐weighted contrast at physiological pH, while acidic conditions trigger disassembly, activating T1‐weighted ...
Xumin Huang, Liwei Liu, Jiayuan Zhu, Xinghao Hu, Changkui Fu, Yao Wang, Lining Arnold Ju, Thomas P. Davis, Andriansjah Rukmana, Shaohua Ma, Zheng Zhang, Ruirui Qiao   +11 more
wiley   +1 more source

A <i>de novo VPS16</i> missense variant blocks autophagic flux and extends DYT-<i>VPS16</i> into infancy. [PDF]

Autophagy Rep
Gonzalez Saez-Diez E, Xue X, Ebrahimi-Fakhari D.   +2 more
europepmc   +1 more source

Lipid-gated vesicular trafficking directs HSPA1A to the plasma membrane through the endo-lysosomal network. [PDF]

Cell Stress Chaperones
Low J, Cuaresma AB, Martin CK, Badolian A, AlSebaye M, Stahelin RV, Nikolaidis N.   +6 more
europepmc   +1 more source

Initial Molecular Detection of Membrane Damage in Post-Golgi Compartments. [PDF]

Cells
Shiba Y, Saito N.
europepmc   +1 more source

The Odf2 status contributes to asymmetric inheritance of CD133-positive recycling endosomes during cytokinesis in SK-N-DZ human neuroblastoma cells. [PDF]

iScience
Izumi H, Mae T, Tsukita S, Nakagawara A.
europepmc   +1 more source