Results 291 to 300 of about 185,575 (398)

Cationic‐Hydrophilic Di‐Block Copolymers: Surface‐Shielded Vectors for Gene Delivery

Journal of Polymer Science, Volume 63, Issue 6, Page 1419-1432, 15 March 2025.
This study develops synthetic polycationic di‐block carriers for nucleic acid (NA) delivery in gene therapy. Consisting of a cationic block and a hydrophilic block, these carriers efficiently form complexes with NAs and shield them with a protective bioinert layer, enhancing stability during circulation in the bloodstream while reducing undesirable ...
Eliška Hrdá, Ladislav Androvič, Marcela Filipová, Michal Pechar, Richard Laga   +4 more
wiley   +1 more source

RIN3 mutations impairing binding of the Alzheimer's disease-associated protein BIN1 lead to RAB5 hyperactivation and endosomal pathology. [PDF]

Sci Adv
Maaser-Hecker AK, Zellmer JC, Kim M, Bakiasi G, Maiti AK, Curtat MPC, Choi SH, Prokopenko D, Tanzi RE, Bhattacharyya R.   +9 more
europepmc   +1 more source

Heavy Metals in Elecronic Cigarette Aersol Can Accumulate in Lung Epithelial Cells [PDF]

, 2019
Zaman, Rafay
core  

First genome sequence of a European Alternaria brassicae isolate and genes involved in early development of alternaria leaf spot on Brassica juncea

Pest Management Science, EarlyView.
This article reports the first genome sequence of a UK Alternaria brassicae isolate. Dual RNA‐sequencing profiling of A. brassicae‐infected Brassica juncea leaves identified differentially expressed genes involved in pathogenicity and host response pathways in moderately resistant Sej‐2 (2) and moderately susceptible Pusa Jaikisan cultivars.
Kevin M. King, Graham McLaughlin, Chinthani S. Karandeni Dewage, Zedi Gao, David J. Hughes, Jonathan S. West, Henrik U. Stotz   +6 more
wiley   +1 more source

Enzyme-Loaded Microcapsules as Intracellular Organelles for the Degradation of Nanoplastics by Cells. [PDF]

ACS Nano
Liu X, Chow J, Wang W, Dierkes R, Feliu N, Schulz F, Streit WR, Parak WJ.   +7 more
europepmc   +1 more source

Disruption of Retriever Function Impacts Retrograde Trafficking From Endosomes [PDF]

Zebin Li, Zhe Yang, Rohan D. Teasdale
openalex   +1 more source

Maturation of autophagosomes and endosomes: a key role for Rab7.

Biochimica et Biophysica Acta, 2013
J. Hyttinen, M. Niittykoski, A. Salminen, K. Kaarniranta   +3 more
semanticscholar   +1 more source

Mesenchymal stromal cell therapy for rheumatoid arthritis: Long‐term efficacy, safety, and mechanistic insights

Rheumatology &Autoimmunity, EarlyView.
Graphical abstract summarizing the multifactorial pathogenesis of rheumatoid arthritis (RA) and the therapeutic potential of mesenchymal stromal cell (MSC) therapy. MSCs provide promising benefits through their immunomodulatory properties, low immunogenicity, ability to promote tissue repair, and multi‐lineage differentiation, presenting a potential ...
Yingjia Chen, Ruiyu Gao, Xing Guo, Genhong Yao, Xiaojun Tang, Yile E. Liu, Lingyun Sun   +6 more
wiley   +1 more source

Analysis of native Ist1 dynamics reveals multiple pools of ESCRT-III on endosomes. [PDF]

J Cell Biol
Swift KA, Pustova I, Kasberg W, Bowman J, Gopinath K, Voss E, Nelson H, Audhya A.   +7 more
europepmc   +1 more source

Intracellular cholesterol transporters and modulation of hepatic lipid metabolism: implications for diabetic dyslipidaemia and steatosis [PDF]

, 2014
Caridis, Anna-Maria, Dolan, Sharron, Graham, Annette, Soffientini, Ugo   +3 more
core   +1 more source