Results 51 to 60 of about 703 (170)

Platelet biology in regenerative medicine of skeletal muscle [PDF]

, 2018
Platelet‐based applications such as platelet‐rich plasma (PRP) and platelet releasate have gained unprecedented attention in regenerative medicine across a variety of tissues as of late.
Matsakas, A., Naseem, K. M., Scully, D.
core   +1 more source

Immunomodulatory Mechanisms of Chronic Wound Healing: Translational and Clinical Relevance

MedComm, Volume 6, Issue 11, November 2025.
This graphical abstract illustrates the immunomodulation of chronic wounds through various therapeutic approaches aimed at regulating the immune response to promote healing. ABSTRACT Chronic wounds—such as diabetic foot ulcers (DFUs), pressure ulcers (PUs), and venous leg ulcers (VLUs)—pose a serious clinical challenge due to their prolonged ...
Mahrukh Riaz, Muhammad Zohaib Iqbal, Agnes S. Klar, Thomas Biedermann   +3 more
wiley   +1 more source

Optimierung eines orthotopen Pankreaskarzinommodells und seine Anwendung für anti-angiogene Therapieversuche [PDF]

, 2009
Gegenstand dieser Arbeit war die Optimierung bereits bestehender orthotoper Transplantationstechniken von Pankreaskarzinomzelllinien in Tiermodellen. Die optimierten präklinischen Mausmodelle wurden in einer Versuchserie eingesetzt, in die der Effekt ...
Riechmann, Maren
core  

Intracerebral Hemorrhage: Advances, Knowledge Gaps, and Future Directions

MedComm, Volume 6, Issue 11, November 2025.
This review provides a comprehensive synthesis of current research on the epidemiology, pathophysiological mechanisms, imaging characteristics, treatment delays, clinical management strategies, neural repair, and prognostic prediction of intracerebral hemorrhage (ICH).
Tao Liu, Weiwei Jiang, Minzhi Zhang, Shangzhi Xiong, Linan Chen, Xiaoying Chen, Rongcai Jiang   +6 more
wiley   +1 more source

Age-related macular degeneration: experimental and emerging treatments [PDF]

, 2009
Jean Pierre Hubschman, Shantan Reddy, Steven D SchwartzJules Stein Eye Institute, Department of Ophthalmology, University of California, David Geffen School of Medicine, Los Angeles, California, USAPurpose: This essay reviews the experimental treatments ...
Hubschman, Jean Pierre, Reddy, Shantan, Schwartz, Steven D   +2 more
core   +2 more sources

Celecoxib decreases growth and angiogenesis and promotes apoptosis in a tumor cell line resistant to chemotherapy [PDF]

, 2014
Artículo de publicación ISIBackground: During the last few years it has been shown in several laboratories that Celecoxib (Cx), a non-steroidal anti-inflammatory agent (NSAID) normally used for pain and arthritis, mediates antitumor and antiangiogenic ...
Ferreira Vigouroux, Luis Arturo, Fuenzalida Bunster, Luz, Lemus Acuña, Luis, Rosas Chuñil, Carlos Alberto, Sinning Opazo, Mariana   +4 more
core   +2 more sources

Stimuli‐responsive systems: A focus on controlled drug delivery for posterior segment ocular disease

Responsive Materials, Volume 3, Issue 4, November 2025.
This review highlights recent advances in stimuli‐responsive drug delivery for posterior segment diseases, focusing on mechanisms and potential. It also explores mechanically interlocked molecules and bioorthogonal reactions as novel approaches. Challenges and future perspectives are discussed, aiming to bridge the gap between research and clinical ...
Chengzhi Zhang, Jiayi Hou, Yameng Zhao, Yiwen Wang, Kexin Wang, Siyu Li, Yange Wang, Jiehao Zhang, Shenao Ding, Chenxu Zhang, Zongming Song, Ye Tao   +11 more
wiley   +1 more source

Endostatin for fibrosis [PDF]

Science-Business eXchange, 2012
University of Pittsburgh researchers have identified fibrosis as a potential new indication for the cancer therapeutic endostatin. The team designed a modified version of the peptide that reversed fibrosis in ex vivo human skin models and in mice.
openaire   +1 more source

Tumor Endothelial Cells Induce M2 Macrophage Polarization via IL‐4, Enhancing Tumor Growth in Hepatocellular Carcinoma

Cancer Science, Volume 116, Issue 11, Page 2972-2985, November 2025.
Tumor endothelial cells (TECs) promote the polarization of macrophages to M2 subtype by secreting IL‐4. Downregulation of IL‐4 in TECs suppressed M2 polarization and tumor progression. A high abundance of both TECs and M2 macrophages in HCC specimens is associated with poor prognosis.
Daijiro Matoba, Takehiro Noda, Shogo Kobayashi, Yoshihiro Sakano, Kenichi Matsumoto, Chihiro Yamanaka, Kazuki Sasaki, Shinichiro Hasegawa, Yoshifumi Iwagami, Daisaku Yamada, Yoshito Tomimaru, Hirofumi Akita, Hidenori Takahashi, Tadafumi Asaoka, Junzo Shimizu, Hisashi Wada, Yuichiro Doki, Hidetoshi Eguchi   +17 more
wiley   +1 more source

A Systematic Review of Platelet‐Rich Plasma Versus Platelet‐Rich Fibrin for Periorbital Rejuvenation

Journal of Cosmetic Dermatology, Volume 24, Issue 11, November 2025.
ABSTRACT Background Platelet‐rich plasma (PRP) and platelet‐rich fibrin (PRF) have become popular autologous options for facial rejuvenation due to their regenerative potential and favorable safety profiles. The periorbital region remains one of the most challenging treatment sites, as conventional approaches such as hyaluronic acid fillers carry a ...
Catherine F. Sollitto, Maxim Narduzzi, Claire Wolinsky   +2 more
wiley   +1 more source