Results 31 to 40 of about 600 (104)

Proteolytic remodelling of the extracellular matrix by pericytes

The FEBS Journal, Volume 293, Issue 13, Page 3899-3953, July 2026.
Pericytes are specialised perivascular cells intimately connected with endothelial cells and essential for the maintenance of vascular beds. They contribute to the formation and remodelling of the extracellular matrix by actively secreting proteases and protease inhibitors.
Tina Burkhard, Ella Milne, Kate Qian, Paola Campagnolo, Salvatore Santamaria   +4 more
wiley   +1 more source

A patient with a VEGF and endostatin producing gastrointestinal autonomic nerve tumour

, 2004
Tumour associated neovascularisation has been characterised as chaotic and insufficient. This report details the results of the analysis of angiogenic factors in tumour cyst fluid, pleural fluid, and blood from a patient with a gastrointestinal autonomic
Diest, P.J. van, Hanemaaijer, R., Hoekman, K., Pinedo, H.M., Hensbergen, Y. van, Hansma, A.H.G., Kuenen, B.C., Meijer, S.   +7 more
core  

Preclinical and Virtual Models of Mucosal Melanoma: Bridging Translational Gaps in a Rare and Lethal Cancer

Pigment Cell &Melanoma Research, Volume 39, Issue 4, July 2026.
Integrated physical and virtual modeling provides a scalable framework to overcome sample scarcity, recapitulate mucosal melanoma biology, and accelerate translational discovery toward precision medicine. ABSTRACT Mucosal melanoma (MM) is a rare and lethal subtype of melanoma, disproportionately affecting Asian populations and exhibiting distinct ...
Xiangjie Jin, Yuhan Zhang, Yuantai Zhu, Zhiyuan Zhang, Chaoji Shi   +4 more
wiley   +1 more source

Identification of differentially expressed genes in a renal cell carcinoma tumor model after endostatin-treatment

, 2004
Endostatin is a cleavage product of collagen XVIII that has shown to inhibit tumor-angiogenesis in experimental tumor models. At present, the exact molecular mechanism of action of endostatin is not completely elucidated.
Löwik, C., Wijngaarden, J. van, Beek, E. van, Bernsen, H., Que, I., Hinsbergh, V.W.M. van, Rooij, K. de   +6 more
core  

Soluble aminopeptidase N/CD13 in malignant and nonmalignant effusions and intratumoral fluid

, 2002
Purpose: On the basis of the finding of marked overexpression in angiogenic microvessels, aminopeptidase N/CD13 has recently been suggested to play a prominent role in tumor angiogenesis. A soluble form of CD13 (sCD13) is present in human plasma, but its
Broxterman, H.J., Verheul, H.M.W., Hanemaaijer, R., Hoekman, K., Pinedo, H.M., Hensbergen, Y. van, Lent, N.A. van, Jorna, A.S.   +7 more
core  

Endostatin in chronic kidney disease: Associations with inflammation, vascular abnormalities, cardiovascular events and survival

, 2021
Tarim, Kayhan, Aydin, Ibrahim, Guler, Ahmet Kerem, Afsar, Barış, Eyileten, Tayfun, Saglamf, Mutlu, Karaman, Murat, Kanbay, Mehmet, Siriopol, Dimitrie, Gezer, Mustafa, Covic, Adrian, Yilmaz, Mahmut Ilker, Unal, Hilmi Umut, Oguz, Yusuf, Tas, Ahmet   +14 more
core   +1 more source

Increased plasma endostatin and GDF15 in indolent non-Hodgkin lymphoma. [PDF]

Ups J Med Sci, 2023
Hidman J, Larsson A, Thulin M, Karlsson T.   +3 more
europepmc   +1 more source

A real-world study of recombinant human endostatin combined with PD-1/PD-L1 blockade and chemotherapy for patients with advanced non-small cell lung cancer negative for actionable molecular biomarkers. [PDF]

Medicine (Baltimore), 2023
Zhao JW, Wang YS, Gu HY, Meng ZN, Wang FW, Wu GQ, Zheng AH.   +6 more
europepmc   +1 more source

Patient With Advanced Aggressive B2 Thymoma Achieved Positive Outcomes Post CAP-Endostar Combination Therapy. [PDF]

Clin Respir J
Zhang M, Zhang J, Zhao K, Yuan X, Zhang J, Liu Y, Lu P.   +6 more
europepmc   +1 more source

Prolonged Ischemia Induces Cellular Stress, Stimulates Extracellular Matrix Remodeling and Compromises the Viability of Human Cancellous Bone Grafts. [PDF]

Cells
Menger MM, Histing T, Poeske F, Schäfer LP, Steinestel K, Löwer-Kiem LM, Menger MD, Laschke MW, Münzer P, Borst O, Braun BJ, Ehnert S, Herath SC.   +12 more
europepmc   +1 more source