The effect of nettle extract consumption and endurance training on the expression of IFN-γ and Endostatin in the liver tissues of mice with melanoma [PDF]
Medical Laboratory JournalBackground: Melanoma is an aggressive malignancy that results from the transformation of pigment-producing melanocytes. This study aimed to investigate the effect of nettle extract consumption and aerobic exercise on the gene expression of IFN-γ and ...
Vahid Zolghadri +3 more
doaj
Celecoxib decreases growth and angiogenesis and promotes apoptosis in a tumor cell line resistant to chemotherapy [PDF]
, 2014 Artículo de publicación ISIBackground: During the last few years it has been shown in several laboratories that Celecoxib (Cx), a non-steroidal anti-inflammatory agent (NSAID) normally used for pain and arthritis, mediates antitumor and antiangiogenic ...
Ferreira Vigouroux, Luis Arturo +4 more
core +2 more sources
Endostatin Induces Endothelial Cell Apoptosis [PDF]
Journal of Biological Chemistry, 1999 Endostatin, a carboxyl-terminal fragment of collagen XVIII, has been shown to regress tumors in mice. In this study, we have analyzed the mechanism of endostatin action on endothelial cells and nonendothelial cells. Endostatin treatment of cow pulmonary artery endothelial cells caused apoptosis, as demonstrated by three methods, annexin V-fluorescein ...
M, Dhanabal +6 more
openaire +2 more sources
Alogliptin Delays the Healing of Traumatic Oral Ulcers in the Buccal Mucosa of Wistar Rats
Fundamental &Clinical Pharmacology, Volume 40, Issue 3, May 2026.ABSTRACT Objective The objective of this study is to evaluate the influence of alogliptin treatment on the healing process of traumatic oral ulcers. Methods Four experimental groups were used: control group (GC) and three test groups treated with oral Alogliptin at 1 (GTA1), 3 (GTA3), and 9 mg/kg/day (GTA9). Ulcer diameter, body weight, glycemic index,
Maria Imaculada de Queiroz Rodrigues +6 more
wiley +1 more source
Increased levels of circulating endostatin are linked to orthostatic hypotension [PDF]
, 2023 Fabrizio Ricci +7 more
openalex +1 more source
An In Situ Embedded B‐MOF Sponge With Shape‐Memory for All‐in‐One Diabetic Wound Therapy
Advanced Healthcare Materials, Volume 15, Issue 14, 10 April 2026.A smart shape‐memory sponge dressing (P1A3@B‐MOF) is developed for accelerated diabetic wound healing. It achieves pH‐responsive corelease of Zn2+ and salvianolic acid B, synergistically providing antibacterial action, repolarizing macrophages to the M2 phenotype, and promoting angiogenesis.
Hai Zhou +11 more
wiley +1 more source
Type XV collagen : Complete structures of the human COL15A1 and mouse Col15a1 genes, location of type XV collagen protein in mature and developing mouse tissues, and generation of mice expressing truncated type XV collagen [PDF]
, 2001 This study was initiated to elucidate the complete genomic structures of type XV collagen in man and mouse and the functional properties of their promoters, as well as to obtain knowledge of the biological role of type XV collagen during development and ...
Muona, Anu
core
Platelet biology in regenerative medicine of skeletal muscle [PDF]
, 2018 Platelet‐based applications such as platelet‐rich plasma (PRP) and platelet releasate have gained unprecedented attention in regenerative medicine across a variety of tissues as of late.
Matsakas, A., Naseem, K. M., Scully, D.
core +1 more source
Unraveling the mysteries of endostatin [PDF]
IUBMB Life, 2009 AbstractEndostatin, a 20‐kDa C‐terminal proteolytic fragment of collagen XVIII, is a specific endogenous angiogenesis inhibitor discovered more than a decade. The structure, stability, and mechanism of actions of endostatin have been extensively investigated during the past 12 years, among which controversial reports remain unclarified.
Yan, Fu +4 more
openaire +2 more sources
Cancer Medicine, Volume 15, Issue 4, April 2026.ABSTRACT Backgroud Different anti‐PD‐1 combination therapies are used to improve response rate and combat drug resistance for melanoma in the real world of China. While the reported safety data has remained scarce, especially for the controversial use of interferon.
Yuan Qiao +21 more
wiley +1 more source