Insights into differential endostatin activity
commentary to Opposite Effects of Endostatin on Different Endothelial Cells Annette Schmidt, Klaus Addicks and Wilhelm ...
Timothy K, Maclachlan +1 more
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The Extracellular Matrix and Blood Vessel Formation: Not Just a Scaffold [PDF]
The extracellular matrix plays a number of important roles, among them providing structural support and information to cellular structures such as blood vessels imbedded within it.
Alexopoulou AN +114 more
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Matrix degrading proteases and collagen-derived angiogenesis inhibitors in the regulation of carcinoma cell growth [PDF]
Cancer progression is a complex multi-step process. Two critical steps in tumor growth and invasion are the proteolytic processing of the extracellular matrix environment and the angiogenic switch enabling blood supply into the tumor.
Nyberg, Pia
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Platelet-Rich Plasma in Bone Regeneration: Engineering the Delivery for Improved Clinical Efficacy [PDF]
Human bone is a tissue with a fairly remarkable inherent capacity for regeneration; however, this regenerative capacity has its limitations, and defects larger than a critical size lack the ability to spontaneously heal.
Emily A. Growney Kalaf +3 more
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Endostatin in the pancreas [PDF]
In this issue of the British Journal of Cancer, Brammer and co-workers investigate the status of endostatin expression in human pancreas cancer and normal pancreatic tissue. Endostatin was originally identified from the conditioned media of glioendothelioma cells as an inhibitor of angiogenesis (O'Reilly et al, 1997).
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The roles of collagen XVIII and its endostatin domain in wound healing, hair follicle cycling and bone development [PDF]
Collagen XVIII is a basement membrane proteoglycan, which has three variant N-termini. These variants are coded by two promoters; promoter 1 directs the synthesis of a short variant and promoter 2 directs the synthesis of two longer variants, of which ...
Seppinen, Lotta
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Exploring the complex interplay: gut microbiome, stress, and leptospirosis [PDF]
Leptospirosis, a re-emerging zoonotic disease, remains a significant global health concern, especially amid floods and disasters such as the Kakhovka Dam destruction.
Boisak, Iryna +5 more
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Effects of vascular endothelial growth factor (VEGF-A) and endostatin on bone [PDF]
Angiogenesis is essential for the replacement of cartilage by bone during skeletal growth and regeneration. Vascular endothelial growth factor-A (VEGF-A) is a key regulator of angiogenesis whereas endostatin, a potent inhibitor of endothelial cell ...
Sipola, Annina
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Type XVIII collagen : Characterization of the primary structure and expression pattern of different variants in Xenopus laevis, characterization of the human gene structure and analysis of transgenic mice expressing endostatin [PDF]
In this work the type XVIII collagen has been studied by using several approaches, such as different animal models. The primary structure of frog, Xenopus laevis, type XVIII collagen and the expression pattern of its variants during early embryogenesis ...
Elamaa, Harri
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Prognostic value of tumoral and stromal expression of matrix metalloproteinases 2, 9, 14, tissue inhibitors of matrix metalloproteinase 1, 2 and vascular endothelial growth factor A for cervical cancer patients [PDF]
Orientador: Luiz Carlos ZeferinoDissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Ciências MédicasResumo: Introdução: O câncer do colo do útero é o quarto em incidência e mortalidade em mulheres no mundo.
Azevedo Martins, Jordana Maria, 1992-
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