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Endothelial Dysfunction [PDF]

open access: yesArteriosclerosis, Thrombosis, and Vascular Biology, 2003
Lilach O. Lerman
exaly   +3 more sources
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Endothelial Glycocalyx

Comprehensive Physiology, 2022
Abstract The glycocalyx is a polysaccharide structure that protrudes from the body of a cell. It is primarily conformed of glycoproteins and proteoglycans, which provide communication, electrostatic charge, ionic buffering, permeability, and mechanosensation‐mechanotransduction capabilities to cells.
Christopher A, Foote   +7 more
openaire   +2 more sources

Endothelial Cell Signaling and Endothelial Dysfunction

American Journal of Hypertension, 1995
Endothelial cells have an important protective role in maintaining the normal physiologic function of the vascular wall. When these cells become dysfunctional, they lose this protective influence and they actively promote pathophysiological changes within the blood vessel. This review will discuss some of the extracellular signaling mechanisms employed
Flavahan, NA, Vanhoutte, PM
openaire   +4 more sources

Endothelial microparticles as markers of endothelial dysfunction

Frontiers in Bioscience, 2004
Endothelial microparticles (EMP) are small vesicles released from disturbed endothelial cells (EC). Owing to the central importance of EC injury in thrombotic and inflammatory conditions, assay of EMP as a marker of EC disturbance has come under intensive development by several laboratories.
Lawrence L, Horstman   +3 more
openaire   +2 more sources

Endothelial Glycocalyx

Critical Care Clinics, 2020
The endothelial glycocalyx (EG) is the most luminal layer of the blood vessel, growing on and within the vascular wall. Shedding of the EG plays a central role in many critical illnesses. Degradation of the EG is associated with increased morbidity and mortality. Certain illnesses and iatrogenic interventions can cause degradation of the EG.
Jan, Jedlicka   +2 more
openaire   +2 more sources

Mechanisms and consequences of endothelial cell senescence

Nature Reviews Cardiology, 2022
Endothelial cells are located at the crucial interface between circulating blood and semi-solid tissues and have many important roles in maintaining systemic physiological function.
Samuel I. Bloom   +3 more
semanticscholar   +1 more source

Endothelial Progenitor Cells and Endothelial Microparticles Are Independent Predictors of Endothelial Function

The Journal of Pediatrics, 2014
To examine the degree of microvascular endothelial dysfunction in relation to classical cardiovascular risk factors, arterial stiffness, and numbers of circulating endothelial progenitor cells (EPCs) and endothelial microparticles (EMPs), in obese and normal-weight children.Cross-sectional study with 57 obese (15.2±1.4 years) and 30 normal-weight ...
Bruyndonckx, Luc   +8 more
openaire   +3 more sources

Endothelial progenitors

Blood Cells, Molecules, and Diseases, 2014
The studies carried out during the last two decades have represented a great effort in trying to identify and define cell populations endowed with the phenotypic and functional properties of endothelial progenitors. From these studies a scenario now emerges indicating that in the blood there are very rare endothelial progenitor cells, called ...
Elvira, Pelosi   +2 more
openaire   +2 more sources

Endothelial Adrenoceptors

Journal of Cardiovascular Pharmacology, 2001
alpha2 -Adrenergic agonists cause endothelium-dependent relaxation in a number of isolated blood vessels. This effect is explained by the activation of endothelial alpha 2 -adrenoceptors linked to nitric oxide synthase by G i -coupling proteins. The endothelial response to alpha 2 -adrenergic agonists is blunted considerably after regeneration of the ...
openaire   +4 more sources

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