Results 201 to 210 of about 603,202 (260)

Endothelial activation during the diapedesis of cancer cells: between the kiss of death and therapeutic breakthrough. [PDF]

Cell Mol Biol Lett
Piwowarczyk K, Madeja Z, Siedlar M, Czyż J.   +3 more
europepmc   +1 more source

Cigarette Smoke‐Induced Alveolar Macrophage Senescence via GEM/SIRT3‐Mediated Mitochondrial Dysfunction

Advanced Science, EarlyView.
Cigarette smoke accelerates the aging of immune cells in the lung. By combining human single‐cell sequencing, cell culture, and mouse models, the authors show that the protein GEM drives mitochondrial damage and senescence in alveolar macrophages by suppressing SIRT3.
Jin Wang, Meidan Wei, Xiangrong Song, Jiaxin Zhang, Lisha Zhang, Sixian Chen, Yaoyu Hu, Hui Gao, Jianxiang Li   +8 more
wiley   +1 more source

Clinical practice of the endothelial activation and stress index and its modified versions in multiple myeloma and the effects on prognosis. [PDF]

Ther Adv Hematol
Gursoy V, Gul OO, Kose E, Sadri S.
europepmc   +1 more source

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

Association between Endothelial Activation and Stress Index and mortality in patients with coronary heart disease at intensive care unit: a retrospective cohort study. [PDF]

J Thorac Dis
Dai S, Li B, Zhang Z, Zhang G, Guo S.
europepmc   +1 more source

TME/NIR Dual‐Responsive Zinc‐Based Targeted Nanoagonist for Multimodal Amplification of STING‐Mediated Cancer Immunotherapy

Advanced Science, EarlyView.
A multifunctional nanoagonist (cDZ@IP) enables nano‐metabolite–driven multimodal activation of the STING pathway and enhanced immune recognition, achieving potent antitumor immunity and suppressing tumor growth and metastasis. This strategy highlights the rational design of therapeutic metabolites and establishes a new paradigm bridging nanomedicine ...
Kepeng Hu, Jiawei Wang, Wei Zhang, Zhixuan Wu, Jing Chen, Yujing He, Xiyue Duan, Yaoting He, Xin Xin, Haoyi Xiang, Yijing Wang, Chengwei Wu, Yang Yi, Qing Meng, Yuqian Qiao, Kui Cheng, Xiaojun Long, Zhangfa Song   +17 more
wiley   +1 more source

Association of endothelial activation and stress index with all-cause and cardiovascular mortality in patients with diabetic kidney disease: a population-based prospective study. [PDF]

Diabetol Metab Syndr
Yu W, Zhao J, Xia M, Chen Q, Leng B, Wan L, Liu C, Tang X, Fan X, Hao X, Tang C, Chen G, Liu Y, Yuan F, Liu H.   +14 more
europepmc   +1 more source

Endothelial activation and stress index in risk stratification and treatment optimization for critically ill patients with acute kidney injury: A retrospective cohort study from MIMIC-Ⅳ database. [PDF]

PLoS One
Liang C, Wang K.
europepmc   +1 more source

Remdesivir inhibits endothelial activation and atherosclerosis by coupling TAL1 to TRAF6. [PDF]

J Transl Med
Zhang H, Li R, Huo Q, Li L, Li M, Hu S, Ren C, Wu Z, Zhang C.   +8 more
europepmc   +1 more source

Endothelial activation and stress index links to cardiovascular disease in postmenopausal women mediated by arterial stiffness: A cross-sectional study of National Health and Nutrition Examination Survey 1999-2018. [PDF]

J Int Med Res
Long H, Guo R, Zhou J, Liu G, Chen H, Lin Y.   +5 more
europepmc   +1 more source