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Endothelial Activation Phenotypes and Interleukin-6 Response After Therapeutic Plasma Exchange in Severe COVID-19-Associated Sepsis: A Retrospective Cohort Study. [PDF]
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Estrogen activates endothelial exocytosis
Biochemical and Biophysical Research Communications, 2021Estrogen therapy is used to treat patients with post-menopausal symptoms, such as hot flashes and dyspareunia. Estrogen therapy also decreases the risk of fractures from osteoporosis in post-menopausal women. However, estrogen increases the risk of venous thromboembolic events, such as pulmonary embolism, but the pathways through which estrogen ...
Christine S. Kim +4 more
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Endothelial activation and circulating markers of endothelial activation in kidney disease
Nature Reviews Nephrology, 2010The recognition of a central role for the endothelium in the development of kidney disease or the development of vascular lesions in patients with established renal dysfunction has led to the emergence of methods to test different aspects of endothelium function, including in endothelium injury and repair. Endothelial-cell activation is associated with
Rabelink, T.J. +2 more
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American Journal of Obstetrics and Gynecology, 1996
In preeclampsia markers of endothelial activation (e.g., increased cellular fibronectin and activities that alter in vitro endothelial function (e.g., stimulation of nitric oxide and prostacyclin generation) are increased in the maternal circulation. We tested preeclamptic infant blood for these markers and activities and correlated these findings with
S T, Davidge +4 more
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In preeclampsia markers of endothelial activation (e.g., increased cellular fibronectin and activities that alter in vitro endothelial function (e.g., stimulation of nitric oxide and prostacyclin generation) are increased in the maternal circulation. We tested preeclamptic infant blood for these markers and activities and correlated these findings with
S T, Davidge +4 more
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Markers of Endothelial Activation in Preeclampsia
Clinical Laboratory, 2015The study aimed at finding a laboratory approach to detect endothelial damage in normal pregnancy as well as in pregnancy complicated by preeclampsia using selected markers of endothelial activation.A total of 403 healthy pregnant women without a history of deep vein thrombosis and/or hypertension were prospectively studied.
Martin, Prochazka +8 more
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Endothelial RIG-I activation impairs endothelial function
Biochemical and Biophysical Research Communications, 2012Endothelial dysfunction is a crucial part of the chronic inflammatory atherosclerotic process and is mediated by innate and acquired immune mechanisms. Recent studies suggest that pattern recognition receptors (PRR) specialized in immunorecognition of nucleic acids may play an important role in endothelial biology in a proatherogenic manner.
Tobias, Asdonk +7 more
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ENDOTHELIAL ACTIVATION AND ENDOTHELIAL LEUKOCYTE INTERACTION IN HYPERTENSION [PDF]
Endothelium plays a complex role in vascular biology: regulates blood vessel tone, haemostasis, neutrophil recruitment, hormone trafficking, and fluid filtration.Endothelial adherence and migration of leukocytes into tissue is mediated by different sets of adhesion molecules expressed on activated endothelial cells and their complementary ligands on ...
Mihalj, Martina +2 more
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Endothelial-monocyte-activating polypeptide II
The International Journal of Biochemistry & Cell Biology, 1996Endothelial-monocyte-activating polypeptide II (EMAP II) was initially identified as a product of murine methylcholanthrene A-induced fibrosarcoma cells. The deduced mRNA sequence indicates that EMAP II is synthesised as a 34 kDa precursor molecule (proEMAP) and enzymatically cleaved to produce a biologically active 22 kDa mature polypeptide, which has
M P, Tas, J C, Murray
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Endothelial Activation. Sliding Door to Atherosclerosis
Current Pharmaceutical Design, 2005The vascular endothelium has been long viewed as a simply physical separation between blood and tissue [1]. Over the last two decades a consistent bulk of data demonstrated that endothelium is a widely distributed organ, with a variable degree of heterogeneity among and within tissues [2, 3] and deeply involved in vascular physiology and ...
DESIDERI, GIOVAMBATTISTA, FERRI, CLAUDIO
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Oxidative stress and endothelial activation
Critical Care Medicine, 2002The vascular endothelial surface is a major target of oxidative stress, but we are only now beginning to understand the molecular sources and physiologic consequences of such oxidative activity. Along with exogenous oxidants, provided by professional phagocytes or circulating enzymes, vascular cells generate oxidants in response to cytokine and growth ...
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