Results 261 to 270 of about 932,442 (306)
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Markers of Endothelial Activation in Preeclampsia
Clinical Laboratory, 2015The study aimed at finding a laboratory approach to detect endothelial damage in normal pregnancy as well as in pregnancy complicated by preeclampsia using selected markers of endothelial activation.A total of 403 healthy pregnant women without a history of deep vein thrombosis and/or hypertension were prospectively studied.
Martin, Prochazka +8 more
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Endothelial RIG-I activation impairs endothelial function
Biochemical and Biophysical Research Communications, 2012Endothelial dysfunction is a crucial part of the chronic inflammatory atherosclerotic process and is mediated by innate and acquired immune mechanisms. Recent studies suggest that pattern recognition receptors (PRR) specialized in immunorecognition of nucleic acids may play an important role in endothelial biology in a proatherogenic manner.
Tobias, Asdonk +7 more
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ENDOTHELIAL ACTIVATION AND ENDOTHELIAL LEUKOCYTE INTERACTION IN HYPERTENSION [PDF]
Endothelium plays a complex role in vascular biology: regulates blood vessel tone, haemostasis, neutrophil recruitment, hormone trafficking, and fluid filtration.Endothelial adherence and migration of leukocytes into tissue is mediated by different sets of adhesion molecules expressed on activated endothelial cells and their complementary ligands on ...
Mihalj, Martina +2 more
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Endothelial-monocyte-activating polypeptide II
The International Journal of Biochemistry & Cell Biology, 1996Endothelial-monocyte-activating polypeptide II (EMAP II) was initially identified as a product of murine methylcholanthrene A-induced fibrosarcoma cells. The deduced mRNA sequence indicates that EMAP II is synthesised as a 34 kDa precursor molecule (proEMAP) and enzymatically cleaved to produce a biologically active 22 kDa mature polypeptide, which has
M P, Tas, J C, Murray
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Oxidative stress and endothelial activation
Critical Care Medicine, 2002The vascular endothelial surface is a major target of oxidative stress, but we are only now beginning to understand the molecular sources and physiologic consequences of such oxidative activity. Along with exogenous oxidants, provided by professional phagocytes or circulating enzymes, vascular cells generate oxidants in response to cytokine and growth ...
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Endothelial Activation. Sliding Door to Atherosclerosis
Current Pharmaceutical Design, 2005The vascular endothelium has been long viewed as a simply physical separation between blood and tissue [1]. Over the last two decades a consistent bulk of data demonstrated that endothelium is a widely distributed organ, with a variable degree of heterogeneity among and within tissues [2, 3] and deeply involved in vascular physiology and ...
DESIDERI, GIOVAMBATTISTA, FERRI, CLAUDIO
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Endothelial cell activation in cutaneous vasculitis
Clinical and Experimental Dermatology, 1996Markers of endothelial cell activation were measured in 28 patients presenting with various forms of limited or focal type cutaneous vasculitis. Plasma levels of tissue plasminogen activator antigen (t-PA:Ag), plasminogen activator inhibitor type 1 antigen (PAI-1:Ag) and PAI-1 activity, fibrin plate, von Willebrand factor antigen (vWF:Ag), tissue ...
K M, Jurd +3 more
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OESTROGEN AND ENDOTHELIAL CELL ANGIOGENIC ACTIVITY
Clinical and Experimental Pharmacology and Physiology, 1996SUMMARY1. Increasing evidence suggests that oestrogens protect women from cardiovascular disease during their reproductive years. Although most studies by others have examined the effect of oestrogen on vascular smooth muscle cells, we have evaluated the effect of oestrogen on the angiogenic behaviour of endothelial cells.2.
H W, Schnaper +3 more
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Heparanase activity in cultured endothelial cells
Journal of Cellular Physiology, 1991AbstractThis study was undertaken to identify a heparan sulfate (HS) degradation endoglycosidase (heparanase) in cultured endothelial cells (EC) and to characterize the requirements for its release and subsequent degradation of HS side chains in the subendothelial extracellular matrix (ECM). Intact EC, EC lysates, or EC conditioned media from different
K, Godder +5 more
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Platelet Activation and Endothelial Cell Dysfunction
Critical Care Clinics, 2020In sepsis, coagulation is activated and there is an increased risk of developing a consumptive coagulopathy with attendant increase in mortality. The processes that regulate hemostasis evolved as a component of the inflammatory response to infection.
Tom, van der Poll, Robert I, Parker
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