Results 81 to 90 of about 971,647 (316)

Circulating endothelial progenitor cells and endothelial cells in moyamoya disease [PDF]

Brain and Behavior, 2018
AbstractIntroductionThere is no well‐recognized biomarker for accurately predicting outcome in the presence of moyamoya disease (MMD), a progressive occlusive cerebrovascular disease of the internal carotid arteries or their branches. The aim of this study was to investigate the presence of endothelial progenitor cells (EPCs) and circulating ...
Xiang‐Yang Bao, Yan‐Na Fan, Yi Liu, Qian‐Nan Wang, Yong Zhang, Bing Zhu, Bing Liu, Lian Duan   +7 more
openaire   +2 more sources

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

EGCG Regulates Cell Apoptosis of Human Umbilical Vein Endothelial Cells Grown on 316L Stainless Steel for Stent Implantation

Drug Design, Development and Therapy, 2021
Jinpeng Wang,1 Yue Wang,2 Yuyi Zhao,2 Jinbin Zhao,2 Beilin Zhang,3 Kun Xu2,4 1Department of Cardiology, The Second Hospital of Jilin University, Changchun, 130041, People’s Republic of China; 2Department of Nutrition and Food Hygiene, School of ...
Wang J, Wang Y, Zhao Y, Zhao J, Zhang B, Xu K   +5 more
doaj  

Downregulation of ETS rescues diabetes-induced reduction of endothelial progenitor cells

, 2009
Background Transplantation of vasculogenic progenitor cells (VPC) improves neovascularization after ischemia. However, patients with type 2 diabetes mellitus show a reduced VPC number and impaired functional activity. Previously, we demonstrated that p38
Aicher Alexandra, Chen Linping, Seeger Florian Hartmut, Altschmied Joachim, Haendeler Judith, Alexandra Aicher, Aicher, Alexandra, Judith Haendeler, Seeger, Florian Hartmut, Chen, Linping, Haendeler, Judith, Florian Hartmut Seeger, Linping Chen, Joachim Altschmied, Spyridopoulos Ioakim, Spyridopoulos, Ioakim, Altschmied, Joachim, Ioakim Spyridopoulos   +17 more
core   +1 more source

SIRT1 reduces endothelial activation without affecting vascular function in ApoE-/- mice [PDF]

, 2010
Excessive production of reactive oxygen species (ROS) contributes to progression of atherosclerosis, at least in part by causing endothelial dysfunction and inflammatory activation. The class III histone deacetylase SIRT1 has been implicated in extension
Handschin, C, Heinrich, Kathrin, Schäfer, N, Heinrich, K, Winnik, Stephan, Matter, Christian M., Brokopp, Chad E., Tanner, F C, Tanner, Felix C., Landmesser, Ulf, Breitenstein, A, Handschin, Christoph, Stein, Sokrates, Landmesser, U, Lüscher, Thomas F., Breitenstein, Alexander, Schäfer, Nicola, Besler, C, Winnik, S, Lohmann, C, Lüscher, T F, Lohmann, Christine, Besler, Christian, Matter, C M, Brokopp, C E, Stein, S   +25 more
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Endothelial cells and endothelial progenitor cells in the pathogenesis of systemic sclerosis

European Journal of Rheumatology, 2020
Systemic sclerosis (SSc) is a connective tissue disease characterized by excessive fibrosis, microvasculopathy, and autoimmunity. Endothelial cell (EC) injury and subsequent endothelial cell dysfunction is believed to be an initial event that eventually leads to a vicious pathogenic cycle.
Yuko Ota, Masataka Kuwana
openaire   +3 more sources

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Bevacizumab potentiates chemotherapeutic effect on T-leukemia/lymphoma cells by direct action on tumor endothelial cells

Haematologica, 2011
Vascular endothelial growth factor-A, an angiogenesis stimulator expressed on both tumor endothelial and malignant T cells, is involved in tumor progression in T-leukemia/lymphoma.
Li Wang, Wen-Yu Shi, Fan Yang, Wei Tang, Guillaume Gapihan, Mariana Varna, Zhi-Xiang Shen, Sai-Juan Chen, Christophe Leboeuf, Anne Janin, Wei-Li Zhao   +10 more
doaj   +1 more source

T-cadherin signaling in endothelial cells [PDF]

, 2007
The cadherin superfamily comprises transmembrane glycoproteins that mediate calciumdependent homophilic cell-cell adhesion. In addition to their pivotal role in mechanical adhesion between cells, cadherins have multiple functions in tissue ...
Joshi, Manjunath B
core   +1 more source