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An integrated computational screening strategy identified ursolic acid (UA) and 18β‐glycyrrhetinic acid (18βGA) as a self‐assembling food‐derived molecular pair. The resulting carrier‐free nanoparticles (UA‐18βGA) showed synergistic antiparasitic activity, reduced combined toxicity, and host‐protective anti‐inflammatory effects in zebrafish and murine ...
Shenye Qu +8 more
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Endothelial cell loss following phacoemulsification in the pupillary plane
Journal - American Intra-Ocular Implant Society, 1981Endothelial cell loss following posterior chamber phacoemulsification with and without posterior chamber lens implantation was studied. Postoperative cell counts were taken four months after surgery. Three surgeons participated in this study. Posterior chamber phacoemulsification alone (30 patients) resulted in a mean cell loss of 9%, with a maximum ...
D Michael Colvard +2 more
exaly +3 more sources
Endothelial Cell Loss After Endothelial Keratoplasty
2016Postoperative endothelial cell loss remains a major challenge associated with endothelial keratoplasty (EK) surgery and graft survival.
Dagny Zhu, Neda Shamie
exaly +2 more sources
Endothelial cell loss after autologous rotational keratoplasty
Graefe's Archive for Clinical and Experimental Ophthalmology, 2004To investigate whether it may be possible to ascertain the influence of immunological factors on chronic endothelial cell loss by comparing chronic endothelial cell loss after autologous rotational penetrating keratoplasty and after homologous penetrating keratoplasty.For six patients who had undergone autologous rotational penetrating keratoplasty the
Rainer Sundmacher +2 more
exaly +4 more sources
Do We Overestimate the Endothelial Cell “Loss” After Descemet Membrane Endothelial Keratoplasty?
Current Eye Research, 2013To evaluate how corneal deturgescence after Descemet membrane endothelial keratoplasty (DMEK) influences the posterior corneal surface area and the endothelial cell density (ECD) measurements.A mathematical model was formulated to estimate the increase in posterior corneal surface area associated with postoperative corneal deturgescence and its effect ...
Ruth Quilendrino +2 more
exaly +4 more sources
Manual nucleofragmentation and endothelial cell loss
Journal of Cataract and Refractive Surgery, 1997To compare corneal endothelial cell loss with two cataract surgery techniques: manual nucleofragmentation performed with the Keener nucleus divider and planned extracapsular extraction.Department of Ophthalmology "Memorial Cristóbal Garrigosa," Hospital de l'Esperança, Universitat Autònoma de Barcelona, Spain.Contact specular microscopy was performed ...
A, Matheu +5 more
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Endothelial Cell Loss in Penetrating Keratoplasty
Ophthalmology, 1982Quantitative specular endothelial microscopy was performed on 39 donor corneas before operation and at three and 12 months following penetrating keratoplasty. The central endothelial cell density of these corneas had decreased by 18.3% at three months after operation and by 33.6% at the end of one year.
W W, Culbertson +2 more
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Influence of endothelial cell count of donor's cornea on endothelial cell loss
Graefe's Archive for Clinical and Experimental Ophthalmology, 1983In an experimental study porcine corneas were trephined using different trephining procedures. For every series of trephinations, the initial cell count of the donor cornea was found to play a role in the resulting damage induced by the cutting procedure.
M, Böhnke, J, Draeger, U, Niesmann
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Endothelial cell loss in irradiated optic nerves
Ophthalmology, 2000Radiation optic neuropathy usually occurs months to years after exposure of the anterior visual pathways to ionizing radiation. It is characterized by high signal on gadolinium-enhanced T1-weighted magnetic resonance imaging. Radiation-induced endothelial cell damage resulting in blood-nerve barrier breakdown is hypothesized to produce this pattern ...
L A, Levin, E S, Gragoudas, S, Lessell
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Endothelial Cell Loss During Penetrating Keratoplasty
American Journal of Ophthalmology, 1978We studied the central donor endothelium of 27 clear, penetrating corneal transplants with the specular microscope before and after keratoplasty. We examined the donor corneas first, in vitro, while they were immersed in McCarey-Kaufman preservation medium before transplantation. This preoperative examination proved valuable for screening donor corneas,
W M, Bourne, W M, O'Fallon
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