Results 201 to 210 of about 444,778 (249)

Reversing Temozolomide Resistance in Glioblastoma Based on Cuproptosis‐Mediated Positive Feedback Loop

Advanced Science, EarlyView.
To effectively reverse TMZ resistance, this work proposes a cuproptosis‐mediated positive feedback loop that integrates mitochondrial dysfunction, ATP depletion, AMPK‐p53 signaling, and glycolytic inhibition, ultimately amplifying cell death. This cuproptosis‐mediated feedback loop simultaneously disrupts multiple resistance pathways in GBM, including ...
Wenjie Feng, Rui Yang, Chang Weng, Chen Li, Wanrui Shi, Yang Chen, Yang Yang, Yi Liu, Pengfei Ge, Hao Zhang   +9 more
wiley   +1 more source

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Endothelial Cell Loss After Endothelial Keratoplasty

2016
Postoperative endothelial cell loss remains a major challenge associated with endothelial keratoplasty (EK) surgery and graft survival.
Dagny Zhu, Neda Shamie
exaly   +2 more sources

Endothelial cell loss following phacoemulsification in the pupillary plane

Journal - American Intra-Ocular Implant Society, 1981
Endothelial cell loss following posterior chamber phacoemulsification with and without posterior chamber lens implantation was studied. Postoperative cell counts were taken four months after surgery. Three surgeons participated in this study. Posterior chamber phacoemulsification alone (30 patients) resulted in a mean cell loss of 9%, with a maximum ...
Bernard Davidson, Richard P Kratz, D Michael Colvard   +2 more
exaly   +3 more sources

Endothelial cell loss after autologous rotational keratoplasty

Graefe's Archive for Clinical and Experimental Ophthalmology, 2004
To investigate whether it may be possible to ascertain the influence of immunological factors on chronic endothelial cell loss by comparing chronic endothelial cell loss after autologous rotational penetrating keratoplasty and after homologous penetrating keratoplasty.For six patients who had undergone autologous rotational penetrating keratoplasty the
Daniel Bohringer, Rainer Sundmacher
exaly   +4 more sources

Do We Overestimate the Endothelial Cell “Loss” After Descemet Membrane Endothelial Keratoplasty?

Current Eye Research, 2013
To evaluate how corneal deturgescence after Descemet membrane endothelial keratoplasty (DMEK) influences the posterior corneal surface area and the endothelial cell density (ECD) measurements.A mathematical model was formulated to estimate the increase in posterior corneal surface area associated with postoperative corneal deturgescence and its effect ...
Gerrit Melles, Silke Oellerich, Ruth Quilendrino   +2 more
exaly   +4 more sources

Endothelial Cell Loss in Penetrating Keratoplasty

Ophthalmology, 1982
Quantitative specular endothelial microscopy was performed on 39 donor corneas before operation and at three and 12 months following penetrating keratoplasty. The central endothelial cell density of these corneas had decreased by 18.3% at three months after operation and by 33.6% at the end of one year.
W W, Culbertson, R L, Abbott, R K, Forster   +2 more
openaire   +2 more sources

Manual nucleofragmentation and endothelial cell loss

Journal of Cataract and Refractive Surgery, 1997
To compare corneal endothelial cell loss with two cataract surgery techniques: manual nucleofragmentation performed with the Keener nucleus divider and planned extracapsular extraction.Department of Ophthalmology "Memorial Cristóbal Garrigosa," Hospital de l'Esperança, Universitat Autònoma de Barcelona, Spain.Contact specular microscopy was performed ...
A, Matheu, M, Castilla, F, Duch, M, Martí, J, Lillo, M, Gil   +5 more
openaire   +2 more sources

Influence of endothelial cell count of donor's cornea on endothelial cell loss

Graefe's Archive for Clinical and Experimental Ophthalmology, 1983
In an experimental study porcine corneas were trephined using different trephining procedures. For every series of trephinations, the initial cell count of the donor cornea was found to play a role in the resulting damage induced by the cutting procedure.
M, Böhnke, J, Draeger, U, Niesmann
openaire   +2 more sources

Endothelial cell loss in intraocular lens placement

American Intra-Ocular Implant Society Journal, 1978
Endothelial cell counts were done on eyes selected to fall into four categories: unoperated, intracapsular cataract extraction without implantation, and intracapsular cataract extraction with easy or difficult insertion of an intraocular implant. Uncomplicated cataract extraction resulted in less than 9% cell loss.
R C, Drews, S R, Waltman
openaire   +2 more sources

Graft failure: I. Endothelial cell loss

International Ophthalmology, 2007
Graft failure through endothelial cell loss is a constant threat throughout the lifetime of a corneal graft. It can occur at various time points after transplantation. Primary graft failure has nowadays become increasingly rare owing to meticulous eye banking methods and improved surgical techniques.
Ilse, Claerhout, Hilde, Beele, Philippe, Kestelyn   +2 more
openaire   +2 more sources