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Cancer, a proliferative disease hallmarked by abnormal cell growth and spread, is largely dependent on tumor neoangiogenesis, with evidence of vascular endothelial dysfunction.
P.K.Y. Goon+4 more
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Endothelial cells and endothelial progenitor cells in the pathogenesis of systemic sclerosis
Systemic sclerosis (SSc) is a connective tissue disease characterized by excessive fibrosis, microvasculopathy, and autoimmunity. Endothelial cell (EC) injury and subsequent endothelial cell dysfunction is believed to be an initial event that eventually leads to a vicious pathogenic cycle.
Yuko Ota, Masataka Kuwana
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Endothelial cells and coagulation [PDF]
AbstractEndothelial cells form a monolayer, which lines blood vessels. They are crucially involved in maintaining blood fluidity and providing controlled vascular hemostasis at sites of injury. Thereby endothelial cells facilitate multiple mechanisms, including both procoagulant and anticoagulant, which must be kept in balance.
Katharina Neubauer, Barbara Zieger
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Endothelial Cell Metabolism [PDF]
Endothelial cells (ECs) are more than inert blood vessel lining material. Instead, they are active players in the formation of new blood vessels (angiogenesis) both in health and (life-threatening) diseases. Recently, a new concept arose by which EC metabolism drives angiogenesis in parallel to well-established angiogenic growth factors (e.g., vascular
Guy Eelen+10 more
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Infections and endothelial cells [PDF]
Systemic infection by various pathogens interacts with the endothelium and may result in altered coagulation, vasculitis and atherosclerosis. Endothelium plays a role in the initiation and regulation of both coagulation and fibrinolysis. Exposure of endothelial cells may lead to rapid activation of coagulation via tissue factor (TF) expression and the ...
Keller, T.T.+8 more
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Endothelial cell junctions [PDF]
In the course of a freeze-cleave study on intercellular junctions in the regenerating rat liver, we observed an unusual array of intramembranous particles located in regions of contact between endothelial cells lining the hepatic sinusoids. These arrays were characterized by an accumulation of particles which resembled a zonula occludens in their ...
Yee, Ann G., Revel, Jean-Paul
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Angiogenin and endothelial cells [PDF]
Antiogenin is a potent blood vessel-inducing polypeptide that has a unique ribonucleolytic activity. Initially identified from tumor cells conditioned medium through its ability to induce neovascularization in the chick embryo chorioallantoic membrane assay [1], angiogenin has also been purified from normal plasma [2] which suggested that it might be ...
Badet, Josette+2 more
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Endothelial dysfunction after high-intensity exercise occurs through various mechanisms characterized by decreased nitric oxide (NO) bioavailability. This study aims to determine the relationship between circulating endothelial cells (CEC), endothelial ...
Rias Gesang Kinanti+3 more
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Role of shear stress in endothelial cell morphology and expression of cyclooxygenase isoforms [PDF]
MEDLINE® is the source for the MeSH terms of this document.Objective-: The goal of this study was to examine the effect of chronic heterogeneous shear stress, applied using an orbital shaker, on endothelial cell morphology and the expression of ...
Berson, R.E.+9 more
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Taurine Has no Protective Effect on Rat Corneal Endothelial Cells Injured by Benzalkonium Chloride
Objective To observe the protective effect of 2% taurine on corneal endothelial cells injured by benzalkonium chloride in rats. Methods Six piece of corneal endodermis and elastic layer tissue slices were prepared from 6 eyes of 3 SPF SD rats and ...
GE Jian, SUN Jingfen, WU Yongjie
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