Results 11 to 20 of about 5,786,306 (307)

Endothelial cells and endothelial progenitor cells in the pathogenesis of systemic sclerosis

open access: yesEuropean Journal of Rheumatology, 2020
Systemic sclerosis (SSc) is a connective tissue disease characterized by excessive fibrosis, microvasculopathy, and autoimmunity. Endothelial cell (EC) injury and subsequent endothelial cell dysfunction is believed to be an initial event that eventually leads to a vicious pathogenic cycle.
Yuko Ota, Masataka Kuwana
doaj   +3 more sources

Endothelial Cell Metabolism [PDF]

open access: yesPhysiological Reviews, 2018
Endothelial cells (ECs) are more than inert blood vessel lining material. Instead, they are active players in the formation of new blood vessels (angiogenesis) both in health and (life-threatening) diseases. Recently, a new concept arose by which EC metabolism drives angiogenesis in parallel to well-established angiogenic growth factors (e.g., vascular
Eelen, Guy   +5 more
openaire   +3 more sources

Endothelial cell junctions [PDF]

open access: yesThe Journal of Cell Biology, 1975
In the course of a freeze-cleave study on intercellular junctions in the regenerating rat liver, we observed an unusual array of intramembranous particles located in regions of contact between endothelial cells lining the hepatic sinusoids. These arrays were characterized by an accumulation of particles which resembled a zonula occludens in their ...
Yee, Ann G., Revel, Jean-Paul
openaire   +4 more sources

Angiogenic potential of endothelial progenitor cells and embryonic stem cells [PDF]

open access: yes, 2011
Background: Endothelial progenitor cells (EPCs) are implicated in a range of pathological conditions, suggesting a natural therapeutic role for EPCs in angiogenesis.
Kelly, RDW   +13 more
core   +1 more source

Intracellular S1P generation is essential for S1P-induced motility of human lung endothelial cells : role of sphingosine kinase 1 and S1P lyase [PDF]

open access: yes, 2011
Earlier we have shown that extracellular sphingosine-1-phosphate (S1P) induces migration of human pulmonary artery endothelial cells (HPAECs) through the activation of S1P(1) receptor, PKCε, and PLD2-PKCζ-Rac1 signaling cascade.
Gorshkova, Irina   +9 more
core   +3 more sources

Double-Stranded RNA Attenuates the Barrier Function of Human Pulmonary Artery Endothelial Cells [PDF]

open access: yes, 2013
Circulating RNA may result from excessive cell damage or acute viral infection and can interact with vascular endothelial cells. Despite the obvious clinical implications associated with the presence of circulating RNA, its pathological effects on ...
Heinemann, Akos   +46 more
core   +1 more source

Endothelial cells modulate renin secretion from isolated mouse juxtaglomerular cells [PDF]

open access: yes, 1991
Utilizing cocultures of mouse renal juxtaglomerular cells with bovine microvascular endothelial cells, we have examined whether endothelial cells exert direct influence on renin secretion from renal juxtaglomerular cells.
Kaissling, Brigitte   +7 more
core   +1 more source

Endothelial cells and coagulation [PDF]

open access: yesCell and Tissue Research, 2021
Abstract Endothelial cells form a monolayer, which lines blood vessels. They are crucially involved in maintaining blood fluidity and providing controlled vascular hemostasis at sites of injury. Thereby endothelial cells facilitate multiple mechanisms, including both procoagulant and anticoagulant, which must be kept in balance. Under
Katharina Neubauer, Barbara Zieger
openaire   +3 more sources

Endothelial Cell Heterogeneity [PDF]

open access: yesCold Spring Harbor Perspectives in Medicine, 2003
To review recent advances in the field of endothelial cell heterogeneity, and to apply this knowledge to an understanding of site-specific vasculopathy, including acute lung injury.Published research and review articles in the English language related to endothelial cell biology and endothelial cell heterogeneity.The results of published studies have ...
openaire   +3 more sources

Magnetofection potentiates gene delivery to cultured endothelial cells [PDF]

open access: yes, 2003
Modification of cellular functions by overexpression of genes is increasingly practised for research of signalling pathways, but restricted by limitations of low efficiency. We investigated whether the novel technique of magnetofection (MF) could enhance
Sohn, Hae-Young   +6 more
core   +1 more source

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