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Endothelial Cell Signaling and Endothelial Dysfunction
American Journal of Hypertension, 1995Endothelial cells have an important protective role in maintaining the normal physiologic function of the vascular wall. When these cells become dysfunctional, they lose this protective influence and they actively promote pathophysiological changes within the blood vessel. This review will discuss some of the extracellular signaling mechanisms employed
Flavahan, NA, Vanhoutte, PM
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Endothelium, 2006
The identification of circulating endothelial progenitor cells (EPCs) has prompted an explosion of interest in postnatal vasculogenesis and the role of this mechanism in human health and disease. Previously considered restricted to the embryonic phase, the differentiation in situ of progenitor cells to vascular endothelium is now known to occur in the ...
Brendan, Doyle +2 more
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The identification of circulating endothelial progenitor cells (EPCs) has prompted an explosion of interest in postnatal vasculogenesis and the role of this mechanism in human health and disease. Previously considered restricted to the embryonic phase, the differentiation in situ of progenitor cells to vascular endothelium is now known to occur in the ...
Brendan, Doyle +2 more
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Annual Review of Medicine, 2005
Endothelial progenitor cells are a circulating, bone marrow–derived cell population that appears to participate in both vasculogenesis and vascular homeostasis. Questions persist regarding their functional characteristics, as well as the precise panel of cell surface markers that uniquely define this newly described progenitor cell population.
Aarif Y, Khakoo, Toren, Finkel
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Endothelial progenitor cells are a circulating, bone marrow–derived cell population that appears to participate in both vasculogenesis and vascular homeostasis. Questions persist regarding their functional characteristics, as well as the precise panel of cell surface markers that uniquely define this newly described progenitor cell population.
Aarif Y, Khakoo, Toren, Finkel
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Stem Cell Reviews, 2007
The discovery and subsequent characterization of endothelial precursor cells (EPCs) has stimulated interest in their potential use in older persons. Understanding the mechanisms that underlie EPC availability and function has important clinical implications for this age group.
May J, Reed +3 more
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The discovery and subsequent characterization of endothelial precursor cells (EPCs) has stimulated interest in their potential use in older persons. Understanding the mechanisms that underlie EPC availability and function has important clinical implications for this age group.
May J, Reed +3 more
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Science, 2018
Are endothelial-to-mesenchymal transitions in various vascular pathologies a consequence, cause, or defense?
Elisabetta, Dejana +1 more
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Are endothelial-to-mesenchymal transitions in various vascular pathologies a consequence, cause, or defense?
Elisabetta, Dejana +1 more
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Microscopy Research and Technique, 2003
AbstractHistorically, there has been much debate on the nature of infantile hemangiomas as either congenital malformations or benign neoplasms. Some vascular lesions that are present at birth and evidence no proliferative growth are considered to be congenital malformations; other post‐natal vascular tumors pursue aggressive and possibly lethal ...
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AbstractHistorically, there has been much debate on the nature of infantile hemangiomas as either congenital malformations or benign neoplasms. Some vascular lesions that are present at birth and evidence no proliferative growth are considered to be congenital malformations; other post‐natal vascular tumors pursue aggressive and possibly lethal ...
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2015
The hypothesis that preeclampsia phenotypes result from endothelial cell dysfunction has been followed by decades of evidence demonstrating vascular dysfunction and augmented vascular reactivity in preeclampsia. Multiple studies have detected biomarkers of endothelial activation prior to overt disease.
Davidge, Sandra T. +2 more
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The hypothesis that preeclampsia phenotypes result from endothelial cell dysfunction has been followed by decades of evidence demonstrating vascular dysfunction and augmented vascular reactivity in preeclampsia. Multiple studies have detected biomarkers of endothelial activation prior to overt disease.
Davidge, Sandra T. +2 more
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