Results 241 to 250 of about 1,432,210 (308)

Development of Supercooling Preservation Method for Adherently Cultured Endothelial Cells and Its Application to Microphysiological Systems. [PDF]

Cells
Hikichi M, Shimoda T, Sato K.
europepmc   +1 more source

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source

Transsulfuration metabolism is essential for ferroptosis resistance in quiescent endothelial cells. [PDF]

Cell Death Dis
Oberkersch RE, Lidonnici J, Andreuzza S, Zambon E, Imperato G, Pedretti S, Mitro N, Santoro MM.   +7 more
europepmc   +1 more source

Extracellular Vesicles Modulation by an Adiponectin Receptor Agonist Provides Cardioprotection for Myocardial Ischemic Injury

Advanced Healthcare Materials, EarlyView.
This study demonstrates that ALY688, a drug mimicking the heart‐protective hormone adiponectin, reduces myocardial ischemia injury. ALY688 increases the production of extracellular vesicles, which carry protective cargo including adiponectin itself.
Jialing Tang, Wing Yan Chung, Serena M. Pulente, Yubin Lei, Khang Nguyen, Eddie Tam, Nadya M. Morrow, Ilka Lorenzen‐Schmidt, Fengxia Xiao, Augusto Zani, Dylan Burger, Hye Kyoung Sung, Erin E. Mulvihill, Gary Sweeney   +13 more
wiley   +1 more source

TRPV4 Promotes Histamine Receptor Signaling in Lymphatic Endothelial Cells

Retamal JS, Peng S, Nguyen T, Bandala-Sanchez E, Eriksson EM, McCague RE, Mahdavian NS, Carbone SE, Cao E, Gondin AB, Veldhuis NA, Poole DP.   +11 more
europepmc   +1 more source

PML Is Limiting NLRP3 Inflammasome Activity in Human Endothelial Cells. [PDF]

Cells
Liem CH, Steinemann G, Ghiroltean N, Yvonne Y, Sakr H, Nguyen H, Baum O, Berkholz J.   +7 more
europepmc   +1 more source

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

Advanced Healthcare Materials, EarlyView.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu, Yongjie Tang, Sidi Liu, Tao Xu, Qian Liu   +4 more
wiley   +1 more source

Sex-specific angiogenic responses in endothelial cells-role of the pluripotency factor OCT4. [PDF]

Angiogenesis
Shin J, Hong J, Molokotina I, Krukovets I, Kim E, Tkachenko S, Podrez E, Byzova TV, Cherepanova OA.   +8 more
europepmc   +1 more source

Engineering Resatorvid‐Loaded Sub‐Microgels of Epigallocatechin‐3‐gallate/Hyaluronic Acid to Treat Acute Lung Injury

Advanced Healthcare Materials, EarlyView.
This study presents HAEP@Res sub‐microgels as a lung‐targeted delivery system integrating antioxidant activity with anti‐inflammatory therapy. The sub‐microgels demonstrate excellent biocompatibility, efficiently scavenge intracellular ROS, and downregulate pro‐inflammatory cytokines and genes in a Bleo‐induced ALI mouse model. These findings highlight
Bo Liu, Olawale Alimi Alimi, Benjamin Stearnes, Svetlana Romanova, Brady J. Sillman, Mena Asha Krishnan, Kristina Bailey, Benson J. Edagwa, Huanhuan Joyce Chen, Han‐jun Wang, Bin Duan   +10 more
wiley   +1 more source

Human MAGI1 expression in endothelial cells protects from the development of localized and systemic scleroderma in mice. [PDF]

Arthritis Res Ther
Coquoz O, Schlunke L, Turan I, Schreiner CH, Uccelli I, Serdjebi C, Stalin J.   +6 more
europepmc   +1 more source