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2017
Endothelial cells are a constitutive part of the heart and vasculature and form a crucial link between the cardiovascular system and the immune system. Besides their commonly accepted roles in angiogenesis, hemostasis, and the regulation of vascular tone, they are an essential and active component of immune responses.
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Endothelial cells are a constitutive part of the heart and vasculature and form a crucial link between the cardiovascular system and the immune system. Besides their commonly accepted roles in angiogenesis, hemostasis, and the regulation of vascular tone, they are an essential and active component of immune responses.
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2006
The wear and tear processes that are thought to contribute to human ageing may play an important role in the development of vascular diseases. One such process is cellular senescence. In endothelial cells the senescent phenotype can be induced by a number of factors, including telomere damage, oxidative stress and sustained mitogenic stimulation ...
J D, Erusalimsky, D J, Kurz
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The wear and tear processes that are thought to contribute to human ageing may play an important role in the development of vascular diseases. One such process is cellular senescence. In endothelial cells the senescent phenotype can be induced by a number of factors, including telomere damage, oxidative stress and sustained mitogenic stimulation ...
J D, Erusalimsky, D J, Kurz
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Valve Endothelial Cells - Not Just Any Old Endothelial Cells
Current Vascular Pharmacology, 2016Heart valves are sophisticated cellularised structures that perform a complex series of dynamic functions during each cardiac cycle. The endothelial cells (ECs) that cover both surfaces of the valve, play an important role in ensuring that the valve functions are in an optimal manner.
Napachanok, Mongkoldhumrongkul +2 more
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Cells in focus: endothelial cell
The International Journal of Biochemistry & Cell Biology, 2002The endothelial cell is thought to arise from the splanchnopleuric mesoderm. Endothelial cells form the inner lining of a blood vessel and provides an anticoagulant barrier between the vessel wall and blood. In addition to its role as a selective permeability barrier, the endothelial cell is a unique multifunctional cell with critical basal and ...
Bauer E, Sumpio +2 more
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New England Journal of Medicine, 2003
Vascular endothelial cells form a lining — one cell thick — for all the blood vessels in the body, providing a critical interface between the vessel itself and blood-borne elements.
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Vascular endothelial cells form a lining — one cell thick — for all the blood vessels in the body, providing a critical interface between the vessel itself and blood-borne elements.
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Journal of Cellular Physiology, 2003
AbstractEndothelial cells play a wide variety of critical roles in the control of vascular function. Indeed, since the early 1980s, the accumulating knowledge of the endothelial cell structure as well as of the functional properties of the endothelial cells shifted their role from a passive membrane or barrier to a complex tissue with complex functions
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AbstractEndothelial cells play a wide variety of critical roles in the control of vascular function. Indeed, since the early 1980s, the accumulating knowledge of the endothelial cell structure as well as of the functional properties of the endothelial cells shifted their role from a passive membrane or barrier to a complex tissue with complex functions
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Role of Endothelial Cell–Cell Junctions in Endothelial Permeability
2011The endothelial barrier separates the inner blood compartment from the surrounding tissues. At the molecular level, adhesion molecules accumulate at the endothelial cell-cell junction and contribute to maintain vascular integrity. An increase in the endothelial permeability is frequently associated with the deregulation of junctional adhesion. Here, we
Armelle, Le Guelte, Julie, Gavard
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Cell biology of endothelial cells
Human Pathology, 1987Endothelial cells are a source of physiologically important molecules synthesized therein and secreted to the blood and/or to the subendothelial extracellular matrix. These molecules participate in formation of platelet and fibrin thrombi (e.g., von Willebrand factor and tissue factor) and contribute to antithrombotic properties of the endothelium (e.g.
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Archives of Internal Medicine, 1987
• This summary provides an overview of some of the new information about the metabolic and regulatory functions of vascular endothelial cells and discusses possible important consequences of endothelial abnormalities in disease. (Arch Intern Med1987;147:569-573)
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• This summary provides an overview of some of the new information about the metabolic and regulatory functions of vascular endothelial cells and discusses possible important consequences of endothelial abnormalities in disease. (Arch Intern Med1987;147:569-573)
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Journal of the American Society of Hypertension, 2012
Endothelial dysfunction, the shift from a healthy endothelium to a damaged pro-coagulative, pro-inflammatory, and pro-vasoconstrictive phenotype, is an early event in many chronic diseases that frequently precedes cardiovascular complications. Functional assessment of the endothelium can identify endothelial damage and predict cardiovascular risk ...
Dylan, Burger, Rhian M, Touyz
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Endothelial dysfunction, the shift from a healthy endothelium to a damaged pro-coagulative, pro-inflammatory, and pro-vasoconstrictive phenotype, is an early event in many chronic diseases that frequently precedes cardiovascular complications. Functional assessment of the endothelium can identify endothelial damage and predict cardiovascular risk ...
Dylan, Burger, Rhian M, Touyz
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