Results 71 to 80 of about 5,786,306 (307)

Intact and injured endothelial cells differentially modulate postnatal murine forebrain neural stem cells

Neurobiology of Disease, 2010
Neural stem cells (NSCs) persist in the forebrain subventricular zone (SVZ) within a niche containing endothelial cells. Evidence suggests that endothelial cells stimulate NSC expansion and neurogenesis.
Jennifer M. Plane, Anuska V. Andjelkovic, Richard F. Keep, Jack M. Parent   +3 more
doaj   +1 more source

Assessment of the tissue distribution of transplanted human endothelial progenitor cells by radioactive labeling [PDF]

, 2003
Background— Transplantation of endothelial progenitor cells (EPCs) improves vascularization and left ventricular function after experimental myocardial ischemia.
Dimmeler, S, Henze, E, Aicher, A, Brenner, W, Eckey, T, Zuhayra, M, Badorff, C, Assmus, B, Massoudi, S, Zeiher, AM   +9 more
core  

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

Human endothelial-like differentiated precursor cells maintain their endothelial characteristics when cocultured with mesenchymal stem cell and seeded onto human cancellous bone [PDF]

, 2013
Introduction. Cancellous bone is frequently used for filling bone defects in a clinical setting. It provides favourable conditions for regenerative cells such as MSC and early EPC.
Marzi, Ingo, Dirk Henrich, Barker, John Howard, John Barker, Cancellous Bone, Henrich, Dirk, Ingo Marzi, Seebach, Caroline, Joerg Warzecha, Caroline Seebach, Wilhelm, Kerstin, Warzecha, Jörg, Frank, Johannes, Kerstin Wilhelm, Johannes Frank   +14 more
core   +1 more source

Comparing the paths of Hedgehog release in artificial and natural settings

FEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

Retinoic Acid Promotes Endothelial Cell Cycle Early G1 State to Enable Human Hemogenic Endothelial Cell Specification

Cell Reports, 2020
Summary: Development of blood-forming (hemogenic) endothelial cells that give rise to hematopoietic stem and progenitor cells (HSPCs) is critical during embryogenesis to generate the embryonic and postnatal hematopoietic system.
Jingyao Qiu, Sofia Nordling, Hema H. Vasavada, Eugene C. Butcher, Karen K. Hirschi   +4 more
doaj   +1 more source

Angiogenin and endothelial cells [PDF]

, 1992
Antiogenin is a potent blood vessel-inducing polypeptide that has a unique ribonucleolytic activity. Initially identified from tumor cells conditioned medium through its ability to induce neovascularization in the chick embryo chorioallantoic membrane assay [1], angiogenin has also been purified from normal plasma [2] which suggested that it might be ...
Badet, Josette, Soncin, Fabrice, Barritault, Denis   +2 more
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Obstructive sleep apnea and endothelial progenitor cells

Patient Preference and Adherence, 2013
Qing Wang,1,* Qi Wu,2,* Jing Feng,3,4 Xin Sun5 1The Second Respiratory Department of the First People's Hospital of Kunming, Yunnan, People's Republic of China; 2Tianjin Haihe Hospital, Tianjin, People's Republic of China; 3Respiratory ...
Wang Q, Wu Q, Feng J, Sun X
doaj  

Brain endothelial miR-146a negatively modulates T-cell adhesion through repressing multiple targets to inhibit NF-κB activation. [PDF]

, 2014
Pro-inflammatory cytokine-induced activation of nuclear factor, NF-κB has an important role in leukocyte adhesion to, and subsequent migration across, brain endothelial cells (BECs), which is crucial for the development of neuroinflammatory disorders ...
Susanne MA van der Pol, Male, David K, Cerutti, Camilla, Dongsheng Wu, van der Pol, SM, Sharrack, B, Michael, Gregory J, Simpson, Julie E., Lopez-Ramirez, Miguel A., David Baker, Romero, IA, Baker, David, Basil Sharrack, Simpson, Julie E, Michael, GJ, Wu, Dongsheng, van der Pol, Susanne M A, Hirst, Mark C, Julie E Simpson, Ignacio A Romero, Pryce, Gareth, Baker, D, Gregory J Michael, de Vries, Helga E, Romero, Ignacio A., Hirst, MC, King-Robson, Josh, de Vries, HE, Lopez-Ramirez, Alejandro, Mark C Hirst, David K Male, Male, DK, de Vries, Helga E., Gareth Pryce, Josh King-Robson, Camilla Cerutti, van der Pol, SMA, Romero, Ignacio A, Lopez-Ramirez, Miguel A, Male, David K., King-Robson, J, van der Pol, Susanne M. A., Wu, D, Simpson, JE, Lopez-Ramirez, MA, Miguel A Lopez-Ramirez, van der Pol, Susanne Ma, Cerutti, C, Helga E de Vries, Pryce, G, Hirst, Mark C., Sharrack, Basil, Michael, Gregory J.   +52 more
core   +1 more source