Results 181 to 190 of about 643,976 (288)

ANALYSIS OF THE OBSTETRIC AND GYNECOLOGICAL ANAMNESIS IN WOMEN WITH A THREATENED ABORTION AFFECTED BY THE ENDOTHELIAL DYSFUNCTION

, 2018
L. Dubyk, О. M. Yuzko, L. Nykyfor
openalex   +2 more sources

Extracellular Vesicle‐Delivered tRF‐His‐GTG‐1 Reprograms Neutrophil Lipophagy and Triggers Inflammation in COVID‐19

Advanced Science, EarlyView.
This study identifies platelet‐derived extracellular vesicles as key immunometabolic regulators in COVID‐19. The delivery of tRF‐His‐GTG‐1 to neutrophils activates TLR8mTOR signaling, disrupts lipophagy, and amplifies NET‐mediated inflammation. Importantly, targeting this axis restores neutrophil homeostasis, offering a potential therapeutic strategy ...
Tsai‐Ling Liao, Po‐Yu Liu, Yi‐Ming Chen, Kuo‐Tung Tang, Hung‐Jen Liu, Der‐Yuan Chen   +5 more
wiley   +1 more source

Albuminuria as a non-invasive biomarker of endothelial dysfunction in patients with COPD. [PDF]

Sci Rep
Moaaz M, Mourad S, Baess A, Sweed R.
europepmc   +1 more source

Study of vascular endothelial dysfunction in children with beta-thalassemia major before and after quercetin therapy [PDF]

Fatma Al Zahraa Sherai, Maaly Mohamed Mabrouk, Ibrahim M. Badraia, Adel A. Hagag, Eman M. Elaskary   +4 more
openalex   +1 more source

Cathepsin S–Dependent Protease–Activated Receptor-2 Activation: A New Mechanism of Endothelial Dysfunction [PDF]

, 2015
David J. Nikolic‐Paterson
openalex   +1 more source

TREM2 Drives Neutrophil Extracellular Traps‐Induced Dendritic Cell Maturation and Contributes to Lupus Progression

Advanced Science, EarlyView.
TREM2 recognizes NETs‐derived MPO to promote DC maturation and antigen presentation, thereby exacerbating the autoimmune response in SLE. Mechanistically, TREM2 activation triggers the DAP12/SYK/ERK cascade and enhances NETs internalization by DCs, which in turn activates the cGAS/STING signaling pathway.
Jingxian Shu, Jiabi Liang, Linda Zeng, Shuping Zhong, Xueling Fang, Yating Xu, Yongjian Wu, Xi Huang   +7 more
wiley   +1 more source

Endothelial Dysfunction in Atherosclerosis: Experimental Models and Therapeutics. [PDF]

Biomater Res
Kopych V, Da Costa ADS, Park K.
europepmc   +1 more source

Possible Involvement of Akt Activity in Endothelial Dysfunction in Type 2 Diabetic Mice

, 2008
Yasuhiro Takenouchi, Tsuneo Kobayashi, Takayuki Matsumoto, Katsuo Kamata   +3 more
openalex   +2 more sources

Specific Amelioration of Cerebral Endothelial Dysfunction in Hypertensive Patients Treated With Atorvastatin [PDF]

, 2008
Vicente Lahera, Victoria Cachofeiro
openalex   +1 more source

Gallium‐Doped MXene Nanozymes Protect Liver Through Multi‐Death Pathway Blockade and Hepatocyte Regeneration

Advanced Science, EarlyView.
This study develops gallium‐doped V2C MXene nanozymes (Ga‐V2C) to treat acetaminophen‐induced liver injury through multi‐death pathway blockade and hepatocyte regeneration. Unlike conventional single‐target therapies like N‐acetylcysteine, Ga‐V2C nanozymes enable oxidative stress suppression, apoptosis, and ferroptosis inhibition, and enhanced ...
Xiaopeng Cai, Jingwen Deng, Liqing Wang, Junjie Su, Dongyi Xian, Yilang Yan, Xinyu Yang, Chuanbin Wu, Tingting Peng, Yuan Ding, Guilan Quan, Weilin Wang, Min Zhou, Chao Lu   +13 more
wiley   +1 more source