Results 51 to 60 of about 1,150,560 (201)
Frontiers in Endocrinology, 2021 To assess the variations in pulmonary function and vascular endothelial function in their early stages (without related complications). A total of 162 type 2 diabetes mellitus (T2DM) patients without diabetes complications and 55 healthy people were ...
He Tai +11 more
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The endothelial αENaC contributes to vascular endothelial function in vivo. [PDF]
PLoS ONE, 2017 The Epithelial Sodium Channel (ENaC) is a key player in renal sodium homeostasis. The expression of α β γ ENaC subunits has also been described in the endothelium and vascular smooth muscle, suggesting a role in vascular function.
Antoine Tarjus +9 more
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Endothelial Function in Dyslipidemia: Roles of LDL-Cholesterol, HDL-Cholesterol and Triglycerides
Cells, 2023 Dyslipidemia is associated with endothelial dysfunction. Endothelial dysfunction is the initial step for atherosclerosis, resulting in cardiovascular complications.
Yukihito Higashi
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Effect of allopurinol on phosphocreatine recovery and muscle function in older people with impaired physical function:a randomised controlled trial [PDF]
, 2020 Background: Allopurinol has vascular antioxidant effects and participates in purinergic signalling within muscle. We tested whether allopurinol could improve skeletal muscle energetics and physical function in older people with impaired physical ...
Cavin, Ian +10 more
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Mitochondria and Endothelial Function [PDF]
Circulation Research, 2013 In contrast to their role in cell types with higher energy demands, mitochondria in endothelial cells primarily function in signaling cellular responses to environmental cues. This article provides an overview of key aspects of mitochondrial biology in endothelial cells, including subcellular location, biogenesis, dynamics, autophagy, reactive oxygen ...
Matthew A, Kluge +2 more
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Journal of Pharmacological Sciences, 2003 : Evidence has accumulated that impairment of vascular endothelial function is the initial step in the development of atherosclerosis. One important finding is impairment of the release of endothelium-dependent relaxing factor, which is now thought to be
Masayoshi Hashimoto +3 more
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The role of HDAC2 inhibition in cardioprotection against doxorubicin-induced myocardial injury
Frontiers in Cardiovascular MedicineIntroductionThe molecular mechanisms underlying cardioprotection against doxorubicin (DOX)-induced myocardial injury are poorly understood. Histone deacetylase 2 (HDAC2) plays a significant role in oxidative stress, apoptosis, and mitochondrial ...
Jinsha Liu +7 more
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Endothelial connexins in vascular function
Vascular Biology, 2019 Gap junctions are essential for intercellular crosstalk in blood and lymphatic vasculature. These clusters of intercellular channels ensure direct communication among endothelial cells and between endothelial and smooth muscle cells, and the ...
Aurélie Hautefort +2 more
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Imaging Assessment of Endothelial Function: An Index of Cardiovascular Health
Frontiers in Cardiovascular Medicine, 2022 Endothelial dysfunction is a key early mechanism in a variety of cardiovascular diseases and can be observed in larger conduit arteries as well as smaller resistance vessels (microvascular dysfunction). The presence of endothelial dysfunction is a strong
Anum S. Minhas +8 more
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Impaired endothelial function of the retinal vasculature in hypertensive patients [PDF]
, 2004 <p><b>Background and Purpose:</b> Arterial hypertension constitutes a central factor in the pathogenesis of stroke. We examined endothelial function of the retinal vasculature as a model of the cerebral circulation.</p> <p ...
Delles, C. +5 more
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