Results 161 to 170 of about 514,398 (204)
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Vascular endothelial growth factor
Ophthalmology, 2007Vascular endothelial growth factor (VEGF) signalling is a key stimulant of tumour neovascular growth, survival and capillary permeability, which are critical to solid tumour progression. The intracellular signalling responses that induce an angiogenic phenotype are dependent upon VEGF binding to specific transmembrane receptors on the endothelium and ...
Neil Swanson, Anthony Gershlick
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Vascular endothelial growth factor
Journal of Neuro-Oncology, 1997Vascular endothelial growth factor (VEGF) is a hypoxia-inducible angiogenesis and vascular permeability factor which is expressed in high amounts in perinecrotic palisading cells in human glioblastomas. In vitro VEGF gene expression is enhanced approximately ten times by hypoxia.
Plate, Karlheinz, Warnke, Peter C.
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Vascular Endothelial Growth Factor
2003The striking structural and anatomical parallels between the vasculature and the nervous system is reflected by the fact that these two organ systems appear to use related mechanisms during their development. Thus, it is not surprising that an increasing number of vascular biologists and researchers in the neuroscience field are fascinated by molecules
D GABRILOVICH, M DIKOV
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Intravitreal vascular endothelial growth factor
Graefe's Archive for Clinical and Experimental Ophthalmology, 2014To evaluate whether a specific pre-analytical stabilization regimen is needed for naïve vitreous taps to detect true values of intrinsic VEGF levels.Fourteen consecutive patients with different vitreomacular pathologies without blood-retina-barrier breakdown were scheduled for standard 23-gauge three-port pars plana vitrectomy, and naïve vitreous taps ...
Thomas, Bertelmann +6 more
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Platelet-derived endothelial cell growth factor
Progress in Growth Factor Research, 1991AbstractPlatelet‐derived endothelial cell growth factor (PD‐ECGF) is a 45kDa single chain polypeptide which stimulates endothelial cell growth and chemotaxis in vitro and angiogenesis in vivo. Analysis of a full length PD‐ECGF cDNA revealed an open reading frame coding for 482 amino acids without homology to other known proteins. No signal sequence was
K, Miyazono, K, Usuki, C H, Heldin
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Vascular endothelial growth factor
The International Journal of Biochemistry & Cell Biology, 1998Vascular endothelial growth factor (VEGF) plays a crucial role in angiogenesis in development, in cancer and in other important diseases. VEGF regulates multiple endothelial cell functions including mitogenesis, permeability, vascular tone, and the production of vasoactive molecules.
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Growth factors in endothelial regeneration
Cardiovascular Research, 199381902
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Vascular Endothelial Growth Factor and Angiogenesis
Pharmacological Reviews, 2004Angiogenesis is a hallmark of wound healing, the menstrual cycle, cancer, and various ischemic and inflammatory diseases. A rich variety of pro- and antiangiogenic molecules have already been discovered. Vascular endothelial growth factor (VEGF) is an interesting inducer of angiogenesis and lymphangiogenesis, because it is a highly specific mitogen for
Ann, Hoeben +5 more
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Frontiers in Bioscience, 2007
Angiogenesis is a critical process in both physiological development and many pathological processes. Vascular endothelial growth factor (VEGF)/VEGF receptor (VEGFR) signaling pathway plays a pivotal role in regulating angiogenesis. Many therapeutic agents targeting VEGF and VEGFR are currently in preclinical and clinical development.
Weibo, Cai, Xiaoyuan, Chen
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Angiogenesis is a critical process in both physiological development and many pathological processes. Vascular endothelial growth factor (VEGF)/VEGF receptor (VEGFR) signaling pathway plays a pivotal role in regulating angiogenesis. Many therapeutic agents targeting VEGF and VEGFR are currently in preclinical and clinical development.
Weibo, Cai, Xiaoyuan, Chen
openaire +2 more sources