Results 31 to 40 of about 36,408 (218)

Vascular endothelial growth factor, endostatin levels and clinical features among patients with ulcerative colitis and irritable bowel syndrome and among healthy controls: a cross-sectional analytical study

São Paulo Medical Journal
BACKGROUND: Increased angiogenetic activity in inflammatory bowel disease (IBD) has been shown in previous studies. The aim of this study was to evaluate the relationship of serum vascular endothelial growth factor (VEGF) and endostatin levels with ...
Evrim Kahramanoğlu Aksoy, Hülya Çetinkaya, Berna Savaş, Arzu Ensari, Murat Torgutalp, Cumali Efe   +5 more
doaj   +1 more source

Bilateral same-session intravitreal injections of anti-vascular endothelial growth factors

International Journal of Ophthalmology, 2014
AIM: To document the indications, safety and possible complications of bilateral same-session intravitreal anti-vascular endothelial growth factor (VEGF) injections performed in the ophthalmic operating room.METHODS:A retrospective case series study ...
Nakhleh E. Abu-Yaghi, Ahmed N Shokry, Rami H Abu-Sbeit   +2 more
doaj   +1 more source

The zinc finger domains of PARP‐1 are selectively and potently inhibited by the Au(I)‐based drugs sodium aurothiomalate and aurothioglucose

FEBS Letters, EarlyView.
PARP‐1 is a key enzyme in the DNA damage response, and its inhibition induces cancer cell death via synthetic lethality. Au(I)‐based drugs, such as aurothioglucose and sodium aurothiomalate, block PARP‐1's DNA‐dependent activity by targeting its zinc finger domains.
Uliana Bashtanova, Melinda Jane Duer
wiley   +1 more source

Tumor endothelial inflammation predicts clinical outcome in diverse human cancers. [PDF]

PLoS ONE, 2012
Vascular endothelial cells contribute to the pathogenesis of numerous human diseases by actively regulating the stromal inflammatory response; however, little is known regarding the role of endothelial inflammation in the growth of human tumors and its ...
Sean P Pitroda, Tong Zhou, Randy F Sweis, Matthew Filippo, Edwardine Labay, Michael A Beckett, Helena J Mauceri, Hua Liang, Thomas E Darga, Samantha Perakis, Sajid A Khan, Harold G Sutton, Wei Zhang, Nikolai N Khodarev, Joe G N Garcia, Ralph R Weichselbaum   +15 more
doaj   +1 more source

The Effect of Bioregulators Isolated from Blood Serum and Cornea of the Bovin’s Eye on the Condition of Tissue and Cells of the Rabbit Corneas during Cultivation and Storage

Oftalʹmologiâ, 2021
Objective: to study the condition of the cornea, as well as its epithelial and endothelial cells, while maintaining in vitro at various temperature conditions, under the influence of a number of factors, including bioregulators isolated from blood serum ...
M. S. Krasnov, V. P. Yamskova
doaj   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Factors Affecting Compliance to Anti-Vascular Endothelial Growth Factor Treatment of Diabetic Macular Edema in a Cohort of Jordanian Patients

Clinical Ophthalmology, 2020
Nakhleh E Abu-Yaghi,1 Alaa M Abed,1 Dana F Khlaifat,2 Mohammed B Nawaiseh,2 Laith O Emoush,2 Heba Z AlHajjaj,2 Ala M Abojaradeh,2 Mariana N Hattar,2 Sura K Abusaleem,2 Hashem M Sabbagh,1 Yazan A Abu Gharbieh,1 Sura A Quaqazeh2 1Department of Special ...
Abu-Yaghi NE, Abed AM, Khlaifat DF, Nawaiseh MB, Emoush LO, AlHajjaj HZ, Abojaradeh AM, Hattar MN, Abusaleem SK, Sabbagh HM, Abu Gharbieh YA, Quaqazeh SA   +11 more
doaj  

Increased expression of adenosine 2A receptors in metastatic renal cell carcinoma is associated with poorer response to anti-vascular endothelial growth factor agents and anti-PD-1/Anti-CTLA4 antibodies and shorter survival [PDF]

, 2021
Takao Kamai, Toshiki Kijima, Toyonori Tsuzuki, Akinori Nukui, Hideyuki Abe, Kyoko Arai, Ken‐Ichiro Yoshida   +6 more
openalex   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Role of vascular endothelial growth factor and other growth factors in post-stroke recovery

Annals of Indian Academy of Neurology, 2014
Stroke is a major health problem world-wide and its burden has been rising in last few decades. Until now tissue plasminogen activator is only approved treatment for stroke.
Tanu Talwar, Madakasira Vasantha Padma Srivastava   +1 more
doaj   +1 more source