Results 191 to 200 of about 1,509,178 (304)

Association of the Endothelial Nitric Oxide Synthase (eNOS) G894T Gene Polymorphism With Type 2 Diabetes Mellitus in a Tunisian Population. [PDF]

Endocrinol Diabetes Metab
Ba A, Ayoub M, Aboulkacem S, Belhedi M, Aouni Z, Mazigh C.   +5 more
europepmc   +1 more source

Phloretin Ameliorates Rheumatoid Arthritis by Suppressing HIF‐1α‐Dependent Angiogenesis and Modulating of the Autophagy–Apoptosis Balance

Phytotherapy Research, EarlyView.
ABSTRACT Phloretin (PHL) is an effective monomer component of Phellodendri Chinensis Cortex, Spica Prunellae, and fleshy fruits and exerts therapeutic effects on rheumatoid arthritis (RA). However, the underlying mechanism is yet to be elucidated. Following PHL treatment, therapeutic benefits were evaluated in a collagen‐induced arthritis (CIA) rat ...
Liang Han, Weiji Lin, Xin Ba, Mingjie Hu, Jiahui Yan, Zhe Chen, Kai Qin, Shenghao Tu, Pan Shen   +8 more
wiley   +1 more source

Haploinsufficiency of Endothelial Nitric Oxide Synthase Mitigates Beneficial Effects of Maternal Exercise on Fetal Heart Development During Pregestational Diabetes. [PDF]

J Am Heart Assoc
Van Neck R, Lu X, Pan T, Du I, Wisse LJ, DeRuiter MC, Feng Q.   +6 more
europepmc   +1 more source

Hydrogen Sulfide Improves Outcomes in a Murine Model of Necrotizing Enterocolitis via the Cys440 Residue on Endothelial Nitric Oxide Synthase. [PDF]

J Pediatr Surg, 2023
Hunter CE, Mesfin FM, Manohar K, Liu J, Shelley WC, Brokaw JP, Pecoraro AR, Hosfield BD, Markel TA.   +8 more
europepmc   +1 more source

Nitric Oxide (NO) Traffic in Endothelial NO Synthase [PDF]

Journal of Biological Chemistry, 2002
Anny Slama-Schwok, Michel Négrerie, Vladimir Berka, Jean-Christophe Lambry, Ah-Lim Tsai, Marten H. Vos, Jean-Louis Martin   +6 more
openaire   +1 more source

Potential of Ginkgo biloba Extract to Intervene in Chronic Inflammation‐Related Diseases

Phytotherapy Research, EarlyView.
Chronic inflammation is a pathological mechanism underpinning many diseases. Ginkgo biloba extract (GBE) is well known for its anti‐inflammatory property. GBE and its active constituents have been shown to attenuate pro‐inflammatory cytokine production, suppress nuclear factor kappa B activation, restore redox homeostasis, and modulate disease‐relevant
Yipeng Lin, Inho Cho, Xue Zhu, Ke Wang, Ling Zhu, Wenchang Wong, Michael Murray, Fanfan Zhou   +7 more
wiley   +1 more source

6-Nitrodopamine Release From Mouse Seminal Vesicles Is Dependent on Endothelial Nitric Oxide Synthase (eNOS) Activation. [PDF]

Pharmacol Res Perspect
Britto-Júnior J, Godoy PRC, Lima DO, de Souza VB, Schenka AA, Mariano FV, Jacintho FF, Hermawan I, Shimokawa H, Tsutsui M, Chiavegatto S, Antunes E, De Nucci G.   +12 more
europepmc   +1 more source

Toll‐Like Receptor 4 Signaling in Natural N‐Acylethanolamines and Derivative NAE‐Like Compounds: Mechanisms and Implications for Neuroimmune and Inflammatory Processes in a Systematic Search Approach

Phytotherapy Research, EarlyView.
ABSTRACT N‐acylethanolamines (NAEs) are endogenous fatty acid amides structurally related to the endocannabinoid anandamide and function as bioactive lipid mediators with broad regulatory roles in inflammation and neuroinflammation. Among pattern‐recognition receptors, Toll‐like receptor 4 (TLR4) occupies a central position in innate immune ...
Damiana Scuteri, Francesca Guida, Giacinto Bagetta, Sabatino Maione, Maria Tiziana Corasaniti, Morena Zusso   +5 more
wiley   +1 more source

[Retracted] Prostaglandin E2 reduces swine myocardial ischemia reperfusion injury via increased endothelial nitric oxide synthase and vascular endothelial growth factor expression levels. [PDF]

Biomed Rep
Zhou Y, Yang P, Li A, Ye X, Ren S, Li X.
europepmc   +1 more source

Targeting the CD47–SIRPα phagocytic checkpoint in cancer: Biology, translational opportunities, and next‐generation therapeutic strategies

Smart Molecules, EarlyView.
The CD47–SIRPα axis has emerged as a critical innate immune checkpoint that suppresses macrophage‐mediated phagocytosis through a canonical “don't eat me” signal and enables tumor immune evasion. We comprehensively summarize the structural and biological features of CD47 and the molecular mechanisms underlying CD47‐mediated regulation of phagocytosis ...
Ruimei Zhou, Lingjie Jing, Jianping Zhang, Cheng Guo, Quanjun Yang   +4 more
wiley   +1 more source