Results 201 to 210 of about 1,509,178 (304)

Glutamine Substitution at Lysine⁶⁰⁹ in the Autoinhibitory Region Modulates Catalysis, Uncoupling, and Conformational Dynamics of Endothelial Nitric Oxide Synthase. [PDF]

ACS Omega
Masood M, Khan S, Yameen D, Anwar A, Khan F, Iqbal S, Chaturvedi R, Shamsi A, Haque MM.   +8 more
europepmc   +1 more source

In Vitro and In Vivo Immunomodulatory and Protective Effects of Leukemia Inhibitory Factor‐Engineered Mesenchymal Stromal Cells in Experimental Endotoxemia

Microbiology and Immunology, EarlyView.
ABSTRACT Sepsis is a life‐threatening condition characterized by dysregulated systemic inflammation and high mortality rates. Mesenchymal stem/stromal cells (MSCs) have emerged as promising immunomodulatory agents; however, genetic engineering strategies can enhance their therapeutic efficacy.
Alana Costa de Oliveira, Diego de Carvalho Carneiro, Luiza Carolina França Opretzka, Breno Cardim Barreto, Dahara Keyse Carvalho Silva, Girlaine Café Santos, Cássio Santana Meira, Milena Botelho Pereira Soares   +7 more
wiley   +1 more source

RETRACTION: Arctigenin, a Potent Ingredient of Arctium lappa L., Induces Endothelial Nitric Oxide Synthase and Attenuates Subarachnoid Hemorrhage-Induced Vasospasm through PI3K/Akt Pathway in a Rat Model. [PDF]

Biomed Res Int
Research International B.
europepmc   +1 more source

Impact of endothelial nitric oxide synthase activation on accelerated liver regeneration in a rat ALPPS model. [PDF]

World J Gastroenterol, 2023
Masuo H, Shimizu A, Motoyama H, Kubota K, Notake T, Yoshizawa T, Hosoda K, Yasukawa K, Kobayashi A, Soejima Y.   +9 more
europepmc   +1 more source

Umbilical Cord Blood–Derived Extracellular Vesicles Enhance Neurovascular Regeneration and Improve Erectile Function in a Mouse Model of Bilateral Cavernous Nerve Injury

Andrology, EarlyView.
ABSTRACT Background Erectile dysfunction (ED) secondary to cavernous nerve injury (CNI), such as that occurring after radical prostatectomy, remains a significant clinical challenge, particularly among patients who do not respond to phosphodiesterase Type 5 inhibitors (PDE5i).
Minh Nhat Vo, Guo Nan Yin, Fitri Rahma Fridayana, Yan Huang, Limanjaya Anita, Ju‐Hee Kang, Ji‐Kan Ryu   +6 more
wiley   +1 more source

Association of Endothelial Nitric Oxide Synthase Polymorphisms with Clinical Severity in Patients with COVID-19. [PDF]

J Clin Med
İdikut A, Değer İ, Göktaş G, Karahan S, Sarınç S, Köksal D, Babaoğlu MO, Babaoğlu E.   +7 more
europepmc   +1 more source

Rutaecarpine Improves Hyperlipidemia‐Related Erectile Dysfunction in Rats by Inhibiting Macrophage M1 Polarization‐Induced Corpus Cavernosum Fibrosis

Andrology, EarlyView.
ABSTRACT Background Hyperlipidemia‐related erectile dysfunction (HLED) responds poorly to first‐line treatments such as phosphodiesterase type 5 inhibitors (PDE5Is), emphasizing the need for alternative therapeutic strategies. Rutaecarpine (RUT), a bioactive alkaloid, exhibits significant anti‐inflammatory and anti‐fibrotic effects.
Bocheng Tu, Shiqing Zhu, Peng Hu, Xiaoyu Zhu, Jiaxin Wang, Xinqi Liu, Sen Fu, Tao Wang, Jihong Liu, Kai Cui   +9 more
wiley   +1 more source

SARS-CoV-2 (MA10) Infection Aggravates Cerebrovascular Pathology in Endothelial Nitric Oxide Synthase-Deficient Mice. [PDF]

Viruses
Ismael S, Umar M, Ouvrier B, Hall G, Cummins M, Sapkota A, Talkington G, White AL, Milner R, Khismatullin DB, Bix G.   +10 more
europepmc   +1 more source

6‐Nitrodopamine as a Novel Mediator of Prostatic Smooth Muscle Function in Mouse and Human

Andrology, EarlyView.
ABSTRACT Background Epithelium‐derived catecholamines contribute to local regulation of genitourinary smooth muscle function, but the role of the endogenous 6‐nitrodopamine (6‐ND) in the prostate remains unknown. Objectives To determine whether 6‐ND is produced by mouse and human prostate and its role in smooth muscle regulation.
Alline Araujo Curiel, Fabio Henrique da Silva, Jéssica Mariana Dias, Luise Gabriela Santos Pereira, Douglas Rafael Martins Dias, Amanda Bueno Olivotti, André Almeida Schenka, Valéria Barbosa de Souza, Masato Tsutsui, Fabiola Zakia Monica, Edson Antunes, Gilberto De Nucci, Mariana G. de Oliveira   +12 more
wiley   +1 more source

Role of adenosine A₃ receptor and endothelial nitric oxide synthase in patients with traumatic hemorrhagic shock. [PDF]

Eur J Trauma Emerg Surg
Öztaş Y, Aslan YE, Şener EF, Dana H, Tuğhan E, Günay N, Demiryürek AT.   +6 more
europepmc   +1 more source