Results 161 to 170 of about 5,225,592 (289)

CD248/Endosialin regulates synovial fibroblast state to control coupling of inflammation and bone damage in murine models of immune‐mediated inflammatory arthritis and ageing

open access: yesArthritis &Rheumatology, Accepted Article.
Objective Synovial fibroblasts directly contribute to inflammation and damage in immune‐mediated inflammatory arthritis. CD248/Endosialin is expressed by fibroblasts in the synovium, is highly upregulated during inflammation and has been proposed as a potential therapeutic target.
Samuel Kemble   +12 more
wiley   +1 more source

Human Monocytic Models Reveal Genotype‐Dependent Inflammatory Programs in VEXAS Syndrome

open access: yesArthritis &Rheumatology, Accepted Article.
Objectives VEXAS syndrome is a severe X‐linked autoinflammatory disorder caused by somatic mutations in ubiquitin‐like modifier activating enzyme 1 (UBA1), with clinical outcomes that vary by UBA1 genotype. We aimed to elucidate genotype‐specific inflammatory programs and identify potential therapeutic targets.
Kana Higashitani   +10 more
wiley   +1 more source

A Modified “Suspender‐Type” Traction‐Preservation and Native Ligament Reconstruction Using Hamstring Autograft for Anterior Cruciate Ligament Femoral‐Side Avulsion

open access: yesArthroscopy Techniques, EarlyView.
Abstract Anterior cruciate ligament rupture, a common sports‐related knee injury, often causes instability and functional impairment and increases the long‐term risk of osteoarthritis. Traditional remnant‐preserving anatomical reconstruction is the first‐line treatment for midsubstance tears, but optimal management of femoral‐side avulsion injuries ...
Haiwei Yan, Xiaoling Qin
wiley   +1 more source

Editorial: Recent Advances in Endothelial Progenitor Cells Toward Their Use in Clinical Translation

open access: yesFrontiers in Medicine, 2020
Reinhold J. Medina   +2 more
doaj   +1 more source

Cardiovascular Organoids With Adjustable Endothelial Composition via SOX17‐Engineered hPSCs

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Organoids are considered a novel modeling platform for studying human biology and advancing health research. With the ability to demonstrate complex 3D structure and multicellular interactions, organoids have advanced studies in all major organs as a reliable model.
Po‐Yu Liang   +4 more
wiley   +1 more source

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