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Endothelium, 2006
The identification of circulating endothelial progenitor cells (EPCs) has prompted an explosion of interest in postnatal vasculogenesis and the role of this mechanism in human health and disease. Previously considered restricted to the embryonic phase, the differentiation in situ of progenitor cells to vascular endothelium is now known to occur in the ...
Brendan, Doyle +2 more
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The identification of circulating endothelial progenitor cells (EPCs) has prompted an explosion of interest in postnatal vasculogenesis and the role of this mechanism in human health and disease. Previously considered restricted to the embryonic phase, the differentiation in situ of progenitor cells to vascular endothelium is now known to occur in the ...
Brendan, Doyle +2 more
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Relaxin' with endothelial progenitor cells
Blood, 2012Segal and colleagues in this issue of Blood report their findings about an additional new function for the hormone relaxin: turning on bone marrow–derived endothelial progenitor cells to sites of neoangiogenesis ...
Alice, Wang, S Ananth, Karumanchi
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Endothelial progenitor cells and preeclampsia
Frontiers in Bioscience, 2007The maternal cardiovascular adaptation to pregnancy involves a complex physiologic response to the presence of the growing conceptus, including alterations in maternal vascular endothelial cells that contribute to a profound fall in total systemic vascular resistance.
Hilary S, Gammill +2 more
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Identification of Endothelial Cells and Their Progenitors
2020Blood vessel formation is a key feature in physiologic and pathologic processes. Once considered a homogeneous cell population that functions as a passive physical barrier between blood and tissue, endothelial cells (ECs) are now recognized to be quite "heterogeneous." While numerous attempts to enhance endothelial repair and replacement have been ...
Ellen, Go, Mervin C, Yoder
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Endothelial progenitor cells and thrombosis
Thrombosis Research, 2012The remodelling of existing vessels (i.e. angiogenesis) and the "de novo" vessel formation (i.e. vasculogenesis) occur not only during the embryonic development but also over the entire postnatal life. In 1997, the Asahara group first reported that endothelial progenitor cells circulate in peripheral blood and that they are recruited at sites of ...
Eugenia Rosa, Nuzzolo +2 more
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Characterization of endothelial progenitor cells
Biochemical and Biophysical Research Communications, 2005N ...
FADINI, GIAN PAOLO +2 more
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Endothelial Progenitor Cells for Vasculogenesis
Physiology, 2005Postnatal vasculogenesis is considered to be involved in neovascularization of adult tissues, because bone marrow-derived endothelial progenitor cells (EPCs) were isolated from circulating mononuclear cells in peripheral blood and were shown to incorporate into sites of physiological and pathological neovascularization and to differentiate into mature ...
Satoshi, Murasawa, Takayuki, Asahara
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Circulating Endothelial Cells and Circulating Endothelial Progenitors
2012The roles of circulating endothelial cells (CECs) and circulating endothelial progenitors (CEPs) are currently being investigated in several diseases including cancer and metastases development. Preclinical and clinical data suggest that CEC enumeration might be useful to identify patients who might benefit from anti-angiogenic treatments while CEPs ...
Patrizia, Mancuso +2 more
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Endothelial Progenitor Cells for Neovascularization
2003Available evidence suggests that hematopoietic stem cells (HSCs) and endothelial progenitor cells (EPCs)(Risau et al. 1988; Pardanaud et al. 1989) are derived from a common precursor, the hemangioblast (Flamme and Risau 1992; His 1900; Weiss and Orkin 1996).
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