Results 81 to 90 of about 634,512 (305)

Chemically-defined albumin-free differentiation of human pluripotent stem cells to endothelial progenitor cells

Stem Cell Research, 2015
Human pluripotent stem cell (hPSC)-derived endothelial cells and their progenitors are important for vascular research and therapeutic revascularization.
Xiaoping Bao, Xiaojun Lian, Kaitlin K. Dunn, Mengxuan Shi, Tianxiao Han, Tongcheng Qian, Vijesh J. Bhute, Scott G. Canfield, Sean P. Palecek   +8 more
doaj   +1 more source

A Sacrificial 3D Printed Vessel‐on‐Chip Demonstrates a Versatile Approach to Model Granulation Tissue

Advanced Healthcare Materials, EarlyView.
A novel method that combines 3D printing and organ‐on‐chip technology enables the creation of hollow channels lined with endothelial cells through a fibroblast‐populated connective tissue matrix. The model supports stable metabolic culture conditions, angiogenic sprouting, and immune cell migration, thereby demonstrating an easy and versatile method to
Jonas Jäger, Phil Berger, Andrew I. Morrison, Hendrik Erfurth, Maria Thon, Eva‐Maria Dehne, Susan Gibbs, Jasper J. Koning   +7 more
wiley   +1 more source

Mouse lung contains endothelial progenitors with high capacity to form blood and lymphatic vessels

BMC Cell Biology, 2010
Background Postnatal endothelial progenitor cells (EPCs) have been successfully isolated from whole bone marrow, blood and the walls of conduit vessels. They can, therefore, be classified into circulating and resident progenitor cells.
Barleon Bernhard, Badar Muhammad, Norgall Susanne, Städtler Anna-Maria, Richter Georg, Buttler Kerstin, Rennecke Moritz, Schniedermann Judith, May Tobias, Wilting Jörg, Weich Herbert A   +10 more
doaj   +1 more source

Endothelial Progenitor Cells in Mixed Cryoglobulinemia

The Journal of Rheumatology, 2010
Objective.Endothelial progenitor cells (EPC) are a rare population of circulating cells involved in vascular homeostasis. Our aim was to analyze EPC in patients with mixed cryoglobulinemia (MC).Methods.EPC were evaluated by cytometry according to guidelines of the International Society for Hematotherapy and Graft Engineering in 17 patients with MC and ...
MARCHI F, CHIMENTI D, TAVONI A, DELLA ROSSA A, BOMBARDIERI, STEFANO, MIGLIORINI, PAOLA   +5 more
openaire   +4 more sources

Microphysiological Systems of Lymphatics and Immune Organs

Advanced Healthcare Materials, EarlyView.
This review surveys recent progress in engineering lymphatic microenvironments and immune organoids within microphysiological systems, emphasizing innovative strategies to recreate the biochemical and biophysical complexity of native lymphatic tissues.
Ishita Jain, Ankur Singh, Andrés J. García   +2 more
wiley   +1 more source

Biomimetic Fibrinogen Nanofiber Scaffolds for Vascular Hematopoietic Stem Cell Niche Engineering

Advanced Healthcare Materials, EarlyView.
This study presents an advanced in vitro model of the vascular hematopoietic stem cell niche using self‐assembled fibrinogen nanofibers, mimicking the basement membrane in bone marrow (BM) sinusoids. The model supports the coculture of microvascular endothelial cells, stromal cells, and hematopoietic stem and progenitor cells, providing insights into ...
Sophia Lena Meermeyer, Arundhati Joshi, Constantin von Kaisenberg, Dorothea Brüggemann, Cornelia Lee‐Thedieck   +4 more
wiley   +1 more source

Translational Research of the Acute Effects of Negative Emotions on Vascular Endothelial Health: Findings From a Randomized Controlled Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Provoked anger is associated with an increased risk of cardiovascular disease events. The underlying mechanism linking provoked anger as well as other core negative emotions including anxiety and sadness to cardiovascular disease remain ...
Daichi Shimbo, Morgan T. Cohen, Matthew McGoldrick, Ipek Ensari, Keith M. Diaz, Jie Fu, Andrea T. Duran, Shuqing Zhao, Jerry M. Suls, Matthew M. Burg, William F. Chaplin   +10 more
doaj   +1 more source

Low Ethanol Concentrations Promote Endothelial Progenitor Cell Capacity and Reparative Function

Cardiovascular Therapeutics, 2020
Background. Endothelial progenitor cells (EPCs) are recruited to injured endothelium and contribute to its regeneration. There is evidence that moderate ethanol consumption prevents the development and progression of atherosclerosis in a variety of in ...
Lars Brodowski, Bianca Schröder-Heurich, Berina Kipke, Cara Schmidt, Constantin S. von Kaisenberg, Frauke von Versen-Höynck   +5 more
doaj   +1 more source

Platelet Lysate–Enriched Human Induced Pluripotent Stem Cell–Derived Chondrocyte Sheets for Bone Defect Repair via Endochondral Ossification

Advanced Healthcare Materials, EarlyView.
Human iPSC‐derived hypertrophic chondrocyte sheet promotes bone regeneration. Abstract Bone defects are a major clinical challenge, primarily owing to the limited self‐healing capacity of bones and the high risk of complications associated with conventional treatment strategies.
Yiwei Chen, Jiali Lin, Jiapeng Li, Yiwei Hu, Jiansen Su, Yu Miao, Lanlan Wang, Qian Tang, Changqing Zhang, Junhui Yin   +9 more
wiley   +1 more source

A 12-week after-school physical activity programme improves endothelial cell function in overweight and obese children: a randomised controlled study

BMC Pediatrics, 2012
Background Endothelial dysfunction is associated with childhood obesity and is closely linked to the amount and function of endothelial progenitor cells. However, it remains unclear whether endothelial progenitor cells increase with after-school exercise
Park Jong-Hwan, Miyashita Masashi, Kwon Yoo-Chan, Park Hyun-Tae, Kim Eun-Hee, Park Jin-Kee, Park Ki-Beam, Yoon Suk-Ran, Chung Jin-Woong, Nakamura Yoshio, Park Sang-Kab   +10 more
doaj   +1 more source