Results 61 to 70 of about 5,302,488 (329)

Endothelial Progenitor Cells in Mixed Cryoglobulinemia

The Journal of Rheumatology, 2010
Objective.Endothelial progenitor cells (EPC) are a rare population of circulating cells involved in vascular homeostasis. Our aim was to analyze EPC in patients with mixed cryoglobulinemia (MC).Methods.EPC were evaluated by cytometry according to guidelines of the International Society for Hematotherapy and Graft Engineering in 17 patients with MC and ...
MARCHI F, CHIMENTI D, TAVONI A, DELLA ROSSA A, BOMBARDIERI, STEFANO, MIGLIORINI, PAOLA   +5 more
openaire   +4 more sources

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Nestin Protein Is Phosphorylated in Adult Neural Stem/Progenitor Cells and Not Endothelial Progenitor Cells

Stem Cells International, 2012
An intermediate filament protein, Nestin, is known as a neural stem/progenitor cell marker. It was shown to be required for the survival and self-renewal of neural stem cells according to the phenotypes of Nestin knockout mice. Nestin expression has also
Jun Namiki, Sayuri Suzuki, Takeshi Masuda, Yasushi Ishihama, Hideyuki Okano   +4 more
doaj   +1 more source

Single-Cell Transcriptional Profiling of Aortic Endothelium Identifies a Hierarchy from Endovascular Progenitors to Differentiated Cells

Cell Reports, 2019
Summary: The cellular and molecular profiles that govern the endothelial heterogeneity of the circulatory system have yet to be elucidated. Using a data-driven approach to study the endothelial compartment via single-cell RNA sequencing, we characterized
Samuel W. Lukowski, Jatin Patel, Stacey B. Andersen, Seen-Ling Sim, Ho Yi Wong, Joshua Tay, Ingrid Winkler, Joseph E. Powell, Kiarash Khosrotehrani   +8 more
doaj   +1 more source

Differential Effects of Isoxazole-9 on Neural Stem/Progenitor Cells, Oligodendrocyte Precursor Cells, and Endothelial Progenitor Cells. [PDF]

PLoS ONE, 2015
Adult mammalian brain can be plastic after injury and disease. Therefore, boosting endogenous repair mechanisms would be a useful therapeutic approach for neurological disorders.
Seong-Ho Koh, Anna C Liang, Yoko Takahashi, Takakuni Maki, Akihiro Shindo, Noriko Osumi, Jing Zhao, Hong Lin, Julie C Holder, Tsu Tshen Chuang, John D McNeish, Ken Arai, Eng H Lo   +12 more
doaj   +1 more source

Concise Review: Endothelial Progenitor Cells in Regenerative Medicine: Applications and Challenges

Stem Cells Translational Medicine, 2016
Endothelial progenitor cells (EPCs) are currently being studied as candidate cell sources for revascularization strategies. Significant advances have been made in understanding the biology of EPCs, and preclinical studies have demonstrated the ...
M. Chong, Wei-Kai Ng, J. Chan
semanticscholar   +1 more source

Human endothelial-like differentiated precursor cells maintain their endothelial characteristics when cocultured with mesenchymal stem cell and seeded onto human cancellous bone [PDF]

, 2013
Introduction. Cancellous bone is frequently used for filling bone defects in a clinical setting. It provides favourable conditions for regenerative cells such as MSC and early EPC.
Marzi, Ingo, Dirk Henrich, Barker, John Howard, John Barker, Cancellous Bone, Henrich, Dirk, Ingo Marzi, Seebach, Caroline, Joerg Warzecha, Caroline Seebach, Wilhelm, Kerstin, Warzecha, Jörg, Frank, Johannes, Kerstin Wilhelm, Johannes Frank   +14 more
core   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Common endothelial progenitor cell assays identify discrete endothelial progenitor cell populations [PDF]

American Heart Journal, 2009
Multiple measures of endothelial progenitor cells (EPCs) have been described, but there has been limited study of the comparability of these assays. We sought to determine the reproducibility of and correlation between alternative EPC assay methodologies.We simultaneously assessed EPC numbers in 140 patients undergoing cardiac catheterization using the
Thomas J, Povsic, Katherine L, Zavodni, Enrikas, Vainorius, Jennifer F, Kherani, Pascal J, Goldschmidt-Clermont, Eric D, Peterson   +5 more
openaire   +2 more sources

Metformin improves the angiogenic functions of endothelial progenitor cells via activating AMPK/eNOS pathway in diabetic mice

Cardiovascular Diabetology, 2016
BackgroundEndothelial dysfunction has been suggested as a possible causal link between hyperglycemia and microvascular complications in diabetes mellitus. The effect of metformin on endothelial progenitor cells (EPCs) is still unclear.
Jia-Wen Yu, Yaping Deng, Xue Han, Guofei Ren, Jian Cai, Guojun Jiang   +5 more
semanticscholar   +1 more source