Results 41 to 50 of about 129,082 (304)

Human endothelial-like differentiated precursor cells maintain their endothelial characteristics when cocultured with mesenchymal stem cell and seeded onto human cancellous bone [PDF]

, 2013
Introduction. Cancellous bone is frequently used for filling bone defects in a clinical setting. It provides favourable conditions for regenerative cells such as MSC and early EPC.
Marzi, Ingo, Dirk Henrich, Barker, John Howard, John Barker, Cancellous Bone, Henrich, Dirk, Ingo Marzi, Seebach, Caroline, Joerg Warzecha, Caroline Seebach, Wilhelm, Kerstin, Warzecha, Jörg, Frank, Johannes, Kerstin Wilhelm, Johannes Frank   +14 more
core   +1 more source

Endothelial progenitor cells and atherosclerosis

Frontiers in Bioscience, 2013
Atherosclerosis is due to inflammation and endothelial dysfunction and damage caused by a variety of factors. Dysfunction of endothelial progenitor cells (EPCs) that differentiate into mature endothelial cell contributes to the development of atherosclerosis.
Changwu, Ruan, Yan, Shen, Rui, Chen, Zhancheng, Wang, Jin, Li, Yun, Jiang   +5 more
openaire   +2 more sources

The Effects of HMG-CoA Reductase Inhibitor on Vascular Progenitor Cells

Journal of Pharmacological Sciences, 2006
.: Circulating bone marrow-derived vascular progenitor cells contribute to angiogenesis, atherosclerosis, and the response to vascular injury. These vascular progenitor cells consist of two cell groups, endothelial progenitor cells (EPCs) and smooth ...
Kusuyama Takanori, Omura Takashi, Nishiya Daisuke, Enomoto Soichiro, Matsumoto Ryo, Murata Takashi, Takeuchi Kazuhide, Yoshikawa Junichi, Yoshiyama Minoru   +8 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Mouse lung contains endothelial progenitors with high capacity to form blood and lymphatic vessels

BMC Cell Biology, 2010
Background Postnatal endothelial progenitor cells (EPCs) have been successfully isolated from whole bone marrow, blood and the walls of conduit vessels. They can, therefore, be classified into circulating and resident progenitor cells.
Barleon Bernhard, Badar Muhammad, Norgall Susanne, Städtler Anna-Maria, Richter Georg, Buttler Kerstin, Rennecke Moritz, Schniedermann Judith, May Tobias, Wilting Jörg, Weich Herbert A   +10 more
doaj   +1 more source

Increase in circulating endothelial progenitor cells by statin therapy in patients with stable coronary artery disease

, 2001
Background - Therapeutic neovascularization may constitute an important strategy to salvage tissue from critical ischemia. Circulating bone marrow–derived endothelial progenitor cells (EPCs) were shown to augment the neovascularization of ischemic tissue.
Dimmeler, S, Aicher, A, Martin, H, Fichtlscherer, S, Adler, K, Zeiher, AM, Vasa, M   +6 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Circulating humoral factors and endothelial progenitor cells in patients with differing coronary collateral support

, 2004
Background - The mechanisms underlying the variation in collateral formation between patients, even with similar patterns of coronary artery disease, remain unclear.
Bucknall, CA, Meng, Y G, Redwood, SR, Pearson, JD, Redwood, S R, Edwards, R J, Lambiase, PD, Marber, MS, Edwards, RJ, Anthopoulos, P, Rahman, S, Lambiase, P D, Meng, YG, Pearson, J D, Marber, M S; id_orcid, Bucknall, C A   +15 more
core   +1 more source

Circulating progenitor cell count for cardiovascular risk stratification: a pooled analysis [PDF]

, 2010
Background: Circulating progenitor cells (CPC) contribute to the homeostasis of the vessel wall, and a reduced CPC count predicts cardiovascular morbidity and mortality.
Zeiher Andreas M., ZEIHER AM, Saula de Kreutzenberg, Ozaki Takenori, MARUYAMA S, Schmidt-Lucke, Caroline, Andreas M. Zeiher, Takenori Ozaki, Schmidt-Lucke Caroline, Avogaro, Angelo, WERNER N., Meigs, James, Nikos Werner, Meigs James, SCHMIDT LUCKE C, VIGILI DE KREUTZENBERG, SAULA, Shoichi Maruyama, Werner, Nikos, Fadini, Gian Paolo, Nickenig, Georg, OZAKI T, Taguchi Akihiko, DIMMELER S, Caroline Schmidt-Lucke, Werner Nikos, Taguchi, Akihiko, Andreas M Zeiher, MEIGS J, NICKENIG G, Maruyama Shoichi, Angelo Avogaro, Ozaki, Takenori, Gian Paolo Fadini, Fadini Gian Paolo, TAGUCHI A, Dimmeler Stefanie, Stefanie Dimmeler, Dimmeler, Stefanie, De Kreutzenberg, Saula, Maruyama, Shoichi, Akihiko Taguchi, Zeiher, Andreas M., James Meigs, Nickenig Georg, Avogaro Angelo, Georg Nickenig, de Kreutzenberg Saula   +46 more
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source