Results 41 to 50 of about 5,302,488 (329)

Protection & regeneration of [beta]-cells: studies using the nod mouse [PDF]

open access: yes, 2009
PhDDiabetes is a chronic disease affecting approximately 250 million people. To date, transplantation-based therapy is the therapy of choice; however, its success is hampered by the scarcity of transplantable human material.
Khoo, Cheen Peen
core   +4 more sources

Circulating progenitor cells and vascular dysfunction in chronic obstructive pulmonary disease. [PDF]

open access: yesPLoS ONE, 2014
In chronic obstructive pulmonary disease (COPD), decreased progenitor cells and impairment of systemic vascular function have been suggested to confer higher cardiovascular risk.
Sandra Pizarro   +11 more
doaj   +1 more source

VEGF secreted by mesenchymal stem cells mediates the differentiation of endothelial progenitor cells into endothelial cells via paracrine mechanisms

open access: yesMolecular Medicine Reports, 2017
Stem cell therapy is a promising treatment strategy for ischemic diseases. Mesenchymal stem cells (MSCs) and endothelial progenitor cells (EPCs) adhere to each other in the bone marrow cavity and in in vitro cultures. We have previously demonstrated that
Quanhu Ge   +11 more
semanticscholar   +1 more source

High calcium bioglass enhances differentiation and survival of endothelial progenitor cells, inducing early vascularization in critical size bone defects [PDF]

open access: yes, 2013
Early vascularization is a prerequisite for successful bone healing and endothelial progenitor cells (EPC), seeded on appropriate biomaterials, can improve vascularization.
Marzi, Ingo   +15 more
core   +2 more sources

Pravastatin Protects Against Avascular Necrosis of Femoral Head via Autophagy

open access: yesFrontiers in Physiology, 2018
Autophagy serves as a stress response and may contribute to the pathogenesis of avascular necrosis of the femoral head induced by steroids. Statins promote angiogenesis and ameliorate endothelial functions through apoptosis inhibition and necrosis of ...
Yun Liao   +6 more
doaj   +1 more source

Endothelial Progenitor Cells May Be Related to Major Amputation after Angioplasty in Patients with Critical Limb Ischemia

open access: yesCells, 2023
Background: Critical limb ischemia represents an advanced stage of peripheral arterial disease. Angioplasty improves blood flow to the limb; however, some patients progress irreversibly to lower limb amputation.
Daniel Santillán-Cortez   +15 more
doaj   +1 more source

Revascularization and endothelial progenitor cells in stroke.

open access: yesAmerican Journal of Physiology - Cell Physiology, 2018
Stroke is one of the leading causes of death and disability worldwide. Tremendous improvements have been achieved in the acute care of stroke patients with the implementation of stroke units, thrombolytic drugs, and endovascular trombectomies.
Gema Esquiva, Alba Grayston, A. Rosell
semanticscholar   +1 more source

Constructing an Isogenic 3D Human Nephrogenic Progenitor Cell Model Composed of Endothelial, Mesenchymal, and SIX2-Positive Renal Progenitor Cells

open access: yesStem Cells International, 2019
Urine has become the source of choice for noninvasive renal epithelial cells and renal stem cells which can be used for generating induced pluripotent stem cells.
Lisa Nguyen   +2 more
doaj   +1 more source

Decreased numbers of circulating endothelial progenitor cells are associated with hyperglycemia in patients with traumatic brain injury

open access: yesNeural Regeneration Research, 2019
Hyperglycemia reduces the number of circulating endothelial progenitor cells, accelerates their senescence and impairs their function. However, the relationship between blood glucose levels and endothelial progenitor cells in peripheral blood of patients
Hui-Jie Wei   +9 more
doaj   +1 more source

Endothelial progenitor cells in age-related vascular remodeling

open access: yesCell Transplantation, 2018
Accumulating evidence has demonstrated that endothelial progenitor cells (EPCs) could facilitate the reendothelialization of injured arteries by replacing the dysfunctional endothelial cells, thereby suppressing the formation of neointima.
Jin-Xiu Yang   +4 more
semanticscholar   +1 more source

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