Results 31 to 40 of about 5,080,538 (250)

Relevance of monocytic features for neovascularization capacity of circulating endothelial progenitor cells [PDF]

, 2003
Background— Transplantation of ex vivo expanded circulating endothelial progenitor cells (EPCs) from peripheral blood mononuclear cells improves the neovascularization after critical ischemia. However, the origin of the endothelial progenitor lineage and
Dimmeler, S, Heeschen, C, Aicher, A, Urbich, C, Zeiher, AM, Dernbach, E   +5 more
core  

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Mouse lung contains endothelial progenitors with high capacity to form blood and lymphatic vessels

BMC Cell Biology, 2010
Background Postnatal endothelial progenitor cells (EPCs) have been successfully isolated from whole bone marrow, blood and the walls of conduit vessels. They can, therefore, be classified into circulating and resident progenitor cells.
Barleon Bernhard, Badar Muhammad, Norgall Susanne, Städtler Anna-Maria, Richter Georg, Buttler Kerstin, Rennecke Moritz, Schniedermann Judith, May Tobias, Wilting Jörg, Weich Herbert A   +10 more
doaj   +1 more source

Novel role of Ras-GTPase Activating Protein SH3 Domain-Binding Protein G3BP in adhesion and migration of 32D myeloid progenitor cells [PDF]

, 2012
Rho GTPases are involved in homing and mobilization of hematopoietic stem and progenitor cells due to their impact on cytoskeleton remodeling. We have previously shown that inhibition of Rho, Rac and Cdc42 clearly impairs adhesion of normal and leukemic ...
Schwarz, Kerstin, Komor, Martina, Aschenbrenner, Frank, Hofmann, Wolf-Karsten, Bug, Gesine, Ruthardt, Martin, Kampfmann, Manuela, Henschler, Reinhard, Rüster, Brigitte Inge   +8 more
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Endothelial stem and progenitor cells (stem cells): (2017 Grover Conference Series)

Pulmonary Circulation, 2017
The capacity of existing blood vessels to give rise to new blood vessels via endothelial cell sprouting is called angiogenesis and is a well-studied biologic process.
Mervin C. Yoder
doaj   +1 more source

Assessment of the tissue distribution of transplanted human endothelial progenitor cells by radioactive labeling [PDF]

, 2003
Background— Transplantation of endothelial progenitor cells (EPCs) improves vascularization and left ventricular function after experimental myocardial ischemia.
Dimmeler, S, Henze, E, Aicher, A, Brenner, W, Eckey, T, Zuhayra, M, Badorff, C, Assmus, B, Massoudi, S, Zeiher, AM   +9 more
core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

The inflammation, vascular repair and injury responses to exercise in fit males with and without Type 1 diabetes: an observational study [PDF]

, 2015
Background: Type 1 diabetes is associated with raised inflammation, impaired endothelial progenitor cell mobilisation and increased markers of vascular injury. Both acute and chronic exercise is known to influence these markers in non diabetic controls,
Wijaya, Stephanie, Gonzalez, JT, Walker, Mark, Emma J Stevenson, Gonzalez, Javier T, Wijaya, S, West, Daniel J., West, Daniel J, Walker, M, Mark Walker, Fahad W Ahmed, Weaver, JU, Stevenson, Emma J., Gonzalez, Javier, West, DJ, Campbell, MD, Shaw, James A, Daniel J West, Ahmed, Fahad W., Stevenson, Emma, Campbell, Matthew, Weaver, Jolanta U., Jolanta U Weaver, Ahmed, Fahad, Shaw, James, Stephanie Wijaya, Shaw, JA, Campbell, Matthew D., Javier T Gonzalez, James A Shaw, Ahmed, Fahad W, Shaw, James A., Matthew D Campbell, Stevenson, Emma J, Weaver, Jolanta U, Stevenson, EJ, Weaver, Jolanta, Ahmed, FW, West, Dan, Gonzalez, Javier T.; id_orcid   +39 more
core   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source