Relevance of monocytic features for neovascularization capacity of circulating endothelial progenitor cells [PDF]
Background— Transplantation of ex vivo expanded circulating endothelial progenitor cells (EPCs) from peripheral blood mononuclear cells improves the neovascularization after critical ischemia. However, the origin of the endothelial progenitor lineage and
Aicher, A +5 more
core +3 more sources
Mobilizing Endothelial Progenitor Cells [PDF]
Mobilization of endogenous endothelial progenitor cells (EPCs) from the bone marrow may be an alternative way to increase neovascularization and may be used as therapeutic option for the treatment of ischemic cardiovascular diseases. In this review, we discuss the EPC mobilizing effects of pro-inflammatory cytokines such as granolocyte monocyte colony ...
Alexandra, Aicher +2 more
openaire +2 more sources
Beneficial effects of reconstituted high-density lipoprotein (rHDL) on circulating CD34+ cells in patients after an acute coronary syndrome [PDF]
Background: High-density lipoproteins (HDL) favorably affect endothelial progenitor cells (EPC). Circulating progenitor cell level and function are impaired in patients with acute coronary syndrome (ACS).
Alam, Mohammad Afaque +15 more
core +13 more sources
Common endothelial progenitor cell assays identify discrete endothelial progenitor cell populations [PDF]
Multiple measures of endothelial progenitor cells (EPCs) have been described, but there has been limited study of the comparability of these assays. We sought to determine the reproducibility of and correlation between alternative EPC assay methodologies.We simultaneously assessed EPC numbers in 140 patients undergoing cardiac catheterization using the
Thomas J, Povsic +5 more
openaire +2 more sources
Human Endothelial Progenitor Cells [PDF]
Human endothelial progenitor cells (EPCs) have been generally defined as circulating cells that express a variety of cell surface markers similar to those expressed by vascular endothelial cells, adhere to endothelium at sites of hypoxia/ischemia, and participate in new vessel formation.
openaire +4 more sources
Does erythropoietin therapy affect circulating endothelial cells in hemodialysis patients?
Anemia is a common complication of chronic kidney disease (CKD). The most common cause of anemia in CKD is erythropoietin deficiency; and the most important cause of mortality in CKD patients is atherosclerotic vascular complications which are ...
T. Bulduk +7 more
doaj +1 more source
Study of the Effect of the Microgravity on the Expression of Angiogenesis Marker in Endothelial Progenitor Cells [PDF]
A study of the effect of microgravity on the endothelial progenitor cells is useful both in understanding cardiac changes in astronauts and in using microgravity as angiogenic stimuli.
Vajihe Zarrinpour, Zahrs Hajebrahimi
doaj +1 more source
Placental growth factor expression is required for bone marrow endothelial cell support of primitive murine hematopoietic cells. [PDF]
Two distinct microenvironmental niches that regulate hematopoietic stem/progenitor cell physiology in the adult bone marrow have been proposed; the endosteal and the vascular niche.
Xiaoying Zhou +2 more
doaj +1 more source
Bone marrow endothelium plays an important role in the homing of hematopoietic stem and progenitor cells upon transplantation, but surprisingly little is known on how the bone marrow endothelial cells regulate local permeability and hematopoietic stem ...
Timo Rademakers +12 more
doaj +1 more source
Summary: Induced pluripotent stem cells (iPSCs) offer a promising platform to model early embryonic developmental processes, to create disease models that can be evaluated by drug screens as well as proof-of-concept experiments for regenerative medicine.
Lucas Lange +7 more
doaj +1 more source

