Results 21 to 30 of about 224,461 (347)

Transdifferentiation of blood-derived human adult endothelial progenitor cells into functionally active cardiomyocytes [PDF]

, 2003
Background - Further to promoting angiogenesis, cell therapy may be an approach for cardiac regeneration. Recent studies suggest that progenitor cells can transdifferentiate into other lineages. However, the transdifferentiation potential of endothelial
Aicher, A, Badorff, C, Brandes, RP, Busse, R, Dimmeler, S, Fleming, I, Popp, R, Rupp, S, Urbich, C, Zeiher, AM   +9 more
core   +1 more source

Profoundly reduced neovascularization capacity of bone marrow mononuclear cells derived from patients with chronic ischemic heart disease [PDF]

, 2004
Background— Cell therapy with bone marrow–derived stem/progenitor cells is a novel option for improving neovascularization and cardiac function in ischemic heart disease.
Aicher, A, Assmus, B, Dimmeler, S, Heeschen, C, Honold, J, Lehmann, R, Martin, H, Walter, DH, Zeiher, AM   +8 more
core   +1 more source

Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia [PDF]

, 2006
Background— Stem and progenitor cell therapy is a novel approach to improve neovascularization and function of ischemic tissue. Enhanced tissue expression of chemoattractant factors such as stromal cell–derived factor 1 and vascular endothelial growth ...
Aicher, A, Dimmeler, S, Heeschen, C, Sasaki, K, Urbich, C, Zeiher, AM   +5 more
core   +1 more source

Specialized mouse embryonic stem cells for studying vascular development. [PDF]

, 2014
Vascular progenitor cells are desirable in a variety of therapeutic strategies; however, the lineage commitment of endothelial and smooth muscle cell from a common progenitor is not well-understood.
Burns, Andrew B, Fan, Yuhong, Glaser, Drew E, Hatano, Rachel, McCloskey, Kara E, Medrzycki, Magdalena   +5 more
core   +1 more source

The level of circulating endothelial progenitor cells may be associated with the occurrence and recurrence of chronic subdural hematoma

Clinics, 2013
OBJECTIVES: The onset of chronic subdural hematoma may be associated with direct or indirect minor injuries to the head or a poorly repaired vascular injury.
Yan Song, Zhitao Wang, Li Liu, Dong Wang, Jianning Zhang   +4 more
doaj   +1 more source

Endothelial progenitor cells in chronic obstructive pulmonary disease and emphysema.

PLoS ONE, 2017
Endothelial injury is implicated in the pathogenesis of COPD and emphysema; however the role of endothelial progenitor cells (EPCs), a marker of endothelial cell repair, and circulating endothelial cells (CECs), a marker of endothelial cell injury, in ...
Margaret F Doyle, Russell P Tracy, Megha A Parikh, Eric A Hoffman, Daichi Shimbo, John H M Austin, Benjamin M Smith, Katja Hueper, Jens Vogel-Claussen, Joao Lima, Antoinette Gomes, Karol Watson, Steven Kawut, R Graham Barr   +13 more
doaj   +1 more source

Folic acid supplementation normalizes the endothelial progenitor cell transcriptome of patients with type 1 diabetes: a case-control pilot study

Cardiovascular Diabetology, 2009
Background Endothelial progenitor cells play an important role in vascular wall repair. Patients with type 1 diabetes have reduced levels of endothelial progenitor cells of which their functional capacity is impaired. Reduced nitric oxide bioavailability
Stubbs Andrew, Pescatori Mario, Fledderus Joost O, de Kleijn Dominique PV, van Oostrom Olivia, Tuinenburg Attie, Lim Sai Kiang, Verhaar Marianne C   +7 more
doaj   +1 more source

Sirt1 expression is associated with CD31 expression in blood cells from patients with chronic obstructive pulmonary disease [PDF]

, 2016
Background: Cigarette smoke induced oxidative stress has been shown to reduce silent information regulator 1 (Sirt1) levels in lung tissue from smokers and patients with COPD patients.
Akai, Masaya, Iguchi, Masaharu, Ishizaki, Takeshi, Kadowaki, Maiko, Kato, Ryo, Mizuno, Shiro, Nakagawa, Ken, Oikawa, Taku, Osanai, Kazuhiro, Shiozaki, Kohei, Toga, Hirohisa, Voelkel, Norbert F   +11 more
core   +2 more sources

Meso-Endothelial Bipotent Progenitors from Human Placenta Display Distinct Molecular and Cellular Identity

Stem Cell Reports, 2018
Summary: The existence of bipotential precursors for both mesenchymal and endothelial stem/progenitor cells in human postnatal life is debated. Here, we hypothesized that such progenitors are present within the human term placenta.
Abbas Shafiee, Jatin Patel, Dietmar W. Hutmacher, Nicholas M. Fisk, Kiarash Khosrotehrani   +4 more
doaj   +1 more source

Hemogenic Endothelial Cells Can Transition to Hematopoietic Stem Cells through a B-1 Lymphocyte-Biased State during Maturation in the Mouse Embryo [PDF]

, 2019
Precursors of hematopoietic stem cells (pre-HSCs) have been identified as intermediate precursors during the maturation process from hemogenic endothelial cells to HSCs in the aorta-gonad-mesonephros (AGM) region of the mouse embryo at embryonic day 10.5.
Azevedo Portilho, Nathalia, Davis, Brian, Hadland, Brandon, Kobayashi, Michihiro, Mishra, Akansha, Tarnawsky, Stefan P., Wei, Haichao, Wenzel, Pamela, Wu, Jiaqian, Yoshimoto, Momoko   +9 more
core   +1 more source