Results 21 to 30 of about 5,302,488 (329)

Endothelial progenitor cells in pregnancy [PDF]

Reproduction, 2007
Abstract The discovery of endothelial progenitor cells has generated considerable interest in the field of vascular biology. These cells arise from a population of circulating mononuclear cells and have the capacity to form new blood vessels and contribute to vascular repair. Circulating endothelial progenitor cell numbers are reduced
Amy O, Robb, Nicholas L, Mills, David E, Newby, Fiona C, Denison   +3 more
openaire   +2 more sources

Hematopoietic stem and progenitor cells use podosomes to transcellularly cross the bone marrow endothelium

Haematologica, 2020
Bone marrow endothelium plays an important role in the homing of hematopoietic stem and progenitor cells upon transplantation, but surprisingly little is known on how the bone marrow endothelial cells regulate local permeability and hematopoietic stem ...
Timo Rademakers, Marieke Goedhart, Mark Hoogenboezem, Alexander García Ponce, Jos van Rijssel, Maryna Samus, Michael Schnoor, Stefan Butz, Stephan Huveneers, Dietmar Vestweber, Martijn A. Nolte, Carlijn Voermans, Jaap D. van Buul   +12 more
doaj   +1 more source

Angiogenic potential of endothelial progenitor cells and embryonic stem cells [PDF]

, 2011
Background: Endothelial progenitor cells (EPCs) are implicated in a range of pathological conditions, suggesting a natural therapeutic role for EPCs in angiogenesis.
St John, Justin, Kelly, Richard, Kelly, RDW, Stuart Egginton, Rae, Peter, Richard DW Kelly, StJohn, JC, Peter C Rae, St. John, Justin C., Justin C St John, Rae, Peter C., Egginton, Stuart, Rae, PC, Egginton, S, Kelly, Richard D. W., St John, JC   +15 more
core   +1 more source

Mobilizing Endothelial Progenitor Cells [PDF]

Hypertension, 2005
Mobilization of endogenous endothelial progenitor cells (EPCs) from the bone marrow may be an alternative way to increase neovascularization and may be used as therapeutic option for the treatment of ischemic cardiovascular diseases. In this review, we discuss the EPC mobilizing effects of pro-inflammatory cytokines such as granolocyte monocyte colony ...
Alexandra, Aicher, Andreas M, Zeiher, Stefanie, Dimmeler   +2 more
openaire   +2 more sources

Inducible Forward Programming of Human Pluripotent Stem Cells to Hemato-endothelial Progenitor Cells with Hematopoietic Progenitor Potential

Stem Cell Reports, 2020
Summary: Induced pluripotent stem cells (iPSCs) offer a promising platform to model early embryonic developmental processes, to create disease models that can be evaluated by drug screens as well as proof-of-concept experiments for regenerative medicine.
Lucas Lange, Dirk Hoffmann, Adrian Schwarzer, Teng-Cheong Ha, Friederike Philipp, Daniela Lenz, Michael Morgan, Axel Schambach   +7 more
doaj   +1 more source

Downregulation of ETS rescues diabetes-induced reduction of endothelial progenitor cells [PDF]

, 2009
Background Transplantation of vasculogenic progenitor cells (VPC) improves neovascularization after ischemia. However, patients with type 2 diabetes mellitus show a reduced VPC number and impaired functional activity. Previously, we demonstrated that p38
Aicher Alexandra, Chen Linping, Seeger Florian Hartmut, Altschmied Joachim, Haendeler Judith, Alexandra Aicher, Aicher, Alexandra, Judith Haendeler, Seeger, Florian Hartmut, Chen, Linping, Haendeler, Judith, Florian Hartmut Seeger, Linping Chen, Joachim Altschmied, Spyridopoulos Ioakim, Spyridopoulos, Ioakim, Altschmied, Joachim, Ioakim Spyridopoulos   +17 more
core   +2 more sources

Endothelial Progenitor Cells in Prehypertension

Current Pharmaceutical Design, 2011
Blood pressure within prehypertensive levels confers higher cardiovascular risk. As prehypertension is also an intermediate stage for full hypertension, a precocious intervention with lifestyle changes or drugs is therefore appealing. Endothelial injury and dysfunction are thought to contribute to cardiovascular risk in prehypertension.
DI STEFANO, ROSSELLA, Barsotti MC, FELICE, FRANCESCA, Vlachopoulos C, BALBARINI, ALBERTO   +4 more
openaire   +4 more sources

The level of circulating endothelial progenitor cells may be associated with the occurrence and recurrence of chronic subdural hematoma

Clinics, 2013
OBJECTIVES: The onset of chronic subdural hematoma may be associated with direct or indirect minor injuries to the head or a poorly repaired vascular injury.
Yan Song, Zhitao Wang, Li Liu, Dong Wang, Jianning Zhang   +4 more
doaj   +1 more source

Endothelial progenitor cells in chronic obstructive pulmonary disease and emphysema.

PLoS ONE, 2017
Endothelial injury is implicated in the pathogenesis of COPD and emphysema; however the role of endothelial progenitor cells (EPCs), a marker of endothelial cell repair, and circulating endothelial cells (CECs), a marker of endothelial cell injury, in ...
Margaret F Doyle, Russell P Tracy, Megha A Parikh, Eric A Hoffman, Daichi Shimbo, John H M Austin, Benjamin M Smith, Katja Hueper, Jens Vogel-Claussen, Joao Lima, Antoinette Gomes, Karol Watson, Steven Kawut, R Graham Barr   +13 more
doaj   +1 more source

Meso-Endothelial Bipotent Progenitors from Human Placenta Display Distinct Molecular and Cellular Identity

Stem Cell Reports, 2018
Summary: The existence of bipotential precursors for both mesenchymal and endothelial stem/progenitor cells in human postnatal life is debated. Here, we hypothesized that such progenitors are present within the human term placenta.
Abbas Shafiee, Jatin Patel, Dietmar W. Hutmacher, Nicholas M. Fisk, Kiarash Khosrotehrani   +4 more
doaj   +1 more source