Results 51 to 60 of about 5,302,488 (329)

Exosomes Derived from Human Endothelial Progenitor Cells Accelerate Cutaneous Wound Healing by Promoting Angiogenesis Through Erk1/2 Signaling

International Journal on Biological Sciences, 2016
Chronic skin wounds represent one of the most common and disabling complications of diabetes. Endothelial progenitor cells (EPCs) are precursors of endothelial cells and can enhance diabetic wound repair by facilitating neovascularization. Recent studies
Jie-Yuan Zhang, Chun-yuan Chen, Bin Hu, X. Niu, Xiao-Lin Liu, Guowei Zhang, Chang-Qing Zhang, Qing Li, Yang Wang   +8 more
semanticscholar   +1 more source

Endothelial progenitor cells and atherosclerosis

Frontiers in Bioscience, 2013
Atherosclerosis is due to inflammation and endothelial dysfunction and damage caused by a variety of factors. Dysfunction of endothelial progenitor cells (EPCs) that differentiate into mature endothelial cell contributes to the development of atherosclerosis.
Changwu, Ruan, Yan, Shen, Rui, Chen, Zhancheng, Wang, Jin, Li, Yun, Jiang   +5 more
openaire   +2 more sources

The Effects of HMG-CoA Reductase Inhibitor on Vascular Progenitor Cells

Journal of Pharmacological Sciences, 2006
.: Circulating bone marrow-derived vascular progenitor cells contribute to angiogenesis, atherosclerosis, and the response to vascular injury. These vascular progenitor cells consist of two cell groups, endothelial progenitor cells (EPCs) and smooth ...
Kusuyama Takanori, Omura Takashi, Nishiya Daisuke, Enomoto Soichiro, Matsumoto Ryo, Murata Takashi, Takeuchi Kazuhide, Yoshikawa Junichi, Yoshiyama Minoru   +8 more
doaj   +1 more source

Endothelial progenitor cells in cardiovascular diseases

Aging Medicine, 2018
Cardiovascular diseases (CVDs) are the leading cause of death in both developed and developing countries. Endothelial progenitor cells (EPCs) are derived from hematopoietic stem cells with powerful function of angiogenesis.
Yumin Qiu, Chan-Juan Zhang, Gao-Xing Zhang, J. Tao   +3 more
semanticscholar   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Mouse lung contains endothelial progenitors with high capacity to form blood and lymphatic vessels

BMC Cell Biology, 2010
Background Postnatal endothelial progenitor cells (EPCs) have been successfully isolated from whole bone marrow, blood and the walls of conduit vessels. They can, therefore, be classified into circulating and resident progenitor cells.
Barleon Bernhard, Badar Muhammad, Norgall Susanne, Städtler Anna-Maria, Richter Georg, Buttler Kerstin, Rennecke Moritz, Schniedermann Judith, May Tobias, Wilting Jörg, Weich Herbert A   +10 more
doaj   +1 more source

Relevance of monocytic features for neovascularization capacity of circulating endothelial progenitor cells [PDF]

, 2003
Background— Transplantation of ex vivo expanded circulating endothelial progenitor cells (EPCs) from peripheral blood mononuclear cells improves the neovascularization after critical ischemia. However, the origin of the endothelial progenitor lineage and
Dimmeler, S, Heeschen, C, Aicher, A, Urbich, C, Zeiher, AM, Dernbach, E   +5 more
core  

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

The inflammation, vascular repair and injury responses to exercise in fit males with and without Type 1 diabetes: an observational study [PDF]

, 2015
Background: Type 1 diabetes is associated with raised inflammation, impaired endothelial progenitor cell mobilisation and increased markers of vascular injury. Both acute and chronic exercise is known to influence these markers in non diabetic controls,
Wijaya, Stephanie, Gonzalez, JT, Walker, Mark, Emma J Stevenson, Gonzalez, Javier T, Wijaya, S, Gonzalez, Javier T., West, Daniel J., West, Daniel J, Walker, M, Mark Walker, Fahad W Ahmed, Weaver, JU, Stevenson, Emma J., Gonzalez, Javier, West, DJ, Campbell, MD, Shaw, James A, Daniel J West, Ahmed, Fahad W., Stevenson, Emma, Campbell, Matthew, Weaver, Jolanta U., Jolanta U Weaver, Ahmed, Fahad, Shaw, James, Stephanie Wijaya, Shaw, JA, Campbell, Matthew D., Javier T Gonzalez, James A Shaw, Ahmed, Fahad W, Shaw, James A., Matthew D Campbell, Stevenson, Emma J, Weaver, Jolanta U, Stevenson, EJ, Weaver, Jolanta, Ahmed, FW, West, Dan   +39 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source