Results 181 to 190 of about 430,240 (358)

Translational Considerations for Injectable Biomaterials and Bioscaffolds to Repair and Regenerate Brain Tissue

Advanced Healthcare Materials, EarlyView.
The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley   +1 more source

Vascular Endothelial Cells Produce Soluble Factors That Mediate the Recovery of Human Hematopoietic Stem Cells after Radiation Injury [PDF]

, 2006
Garrett G. Muramoto, Benny Chen, Xiuyu Cui, Nelson J. Chao, John P. Chute   +4 more
openalex   +1 more source

Human Endometrial Extracellular Matrix Hydrogel Facilitated Endometrial Mesenchymal Stem Cells for Endometrial Regeneration

Advanced Healthcare Materials, EarlyView.
Adequate thickness of the uterine lining is crucial for women with thin or damaged endometrium to achieve pregnancies. Endometrial mesenchymal stem cells (eMSC) can facilitate the cyclical repair and regeneration of the human endometrium. In this study, the human endometrium derived extracellular matrix hydrogel supports the growth of eMSC promoting ...
Jingwen Xu, Philip C N Chiu, Ernest H Y Ng, Sentao Hu, Zi Ye, Liaobing Xin, Lie Ma, Songying Zhang, William S B Yeung, Rachel W S Chan   +9 more
wiley   +1 more source

CD157+ vascular endothelial cells derived from human-induced pluripotent stem cells have high angiogenic potential

Inflammation and Regeneration
Background We previously reported that a vascular endothelial stem cell population resides in pre-existing blood vessels in mice and may contribute to vascular endothelial cells in liver injury or hind limb ischemia models in the long-term.
Ami Takii, Yukika Tanabe, Wenting Li, Hiroki Shiomi, Akane Inoue, Fumitaka Muramatsu, Weizhen Jia, Nobuyuki Takakura   +7 more
doaj   +1 more source

364. The Effect of Overexpression of Vascular Endothelial Growth Factor in Mouse Embryonic Stem Cells on Angiogenesis [PDF]

, 2006
Ying Ka Ingar Lau, Jennifer L. West
openalex   +1 more source

A Human Kidney Tubuloid Model of Repeated Cisplatin‐Induced Cellular Senescence and Fibrosis for Drug Screening

Advanced Healthcare Materials, EarlyView.
Replicating aging and senescence‐related pathophysiological responses in kidney organoids remains a significant challenge. Human adult renal tubular organoid, tubuloids, are successfully developed recapitulating cellular senescence that is the central pathophysiological mechanism of chronic kidney disease (CKD).
Yuki Nakao, Makiko Mori, Yuta Sekiguchi, Iori Morita, Ryota Shindoh, Shintaro Mandai, Tamami Fujiki, Hiroaki Kikuchi, Fumiaki Ando, Koichiro Susa, Takayasu Mori, Ayumi Suzuki, Yuji Nashimoto, Hirokazu Kaji, Yuma Waseda, Soichiro Yoshida, Yasuhisa Fujii, Eisei Sohara, Shinichi Uchida, Kensuke Miyake, Yutaro Mori   +20 more
wiley   +1 more source

Proliferation and neurogenesis of neural stem cells enhanced by cerebral microvascular endothelial cells [PDF]

, 2007
Ying Guo, Dejin Shi, Wensheng Li, Chaofeng Liang, Hui Wang, Zhuopeng Ye, Liping Hu, Huaqiao Wang, Yan Li   +8 more
openalex   +1 more source

Using High‐Throughput Screening to Identify Crosslinking Peptides That Control Cell‐Mediated Matrix Degradation

Advanced Healthcare Materials, EarlyView.
Protease‐degradable hydrogels mimic dynamic cell‐matrix interactions, but controlling hydrogel degradation is a challenge. We screen libraries of peptides to identify sequences that are primarily degraded by membrane‐localized proteases. Crosslinking hydrogels with these peptides enables cell to spread and migrate while reducing matrix degradation ...
Yingjie Wu, Samuel J. Rozans, Abolfazl Salehi Moghaddam, E. Thomas Pashuck   +3 more
wiley   +1 more source

Differentiation, Survival, and Function of Embryonic Stem Cell–Derived Endothelial Cells for Ischemic Heart Disease [PDF]

, 2007
Zongjin Li, Jenny Wu, Ahmad Y. Sheikh, Daniel Kraft, Feng Cao, Xiaoyan Xie, Manishkumar Patel, Sanjiv S. Gambhir, Robert C. Robbins, John P. Cooke, Joseph C. Wu   +10 more
openalex   +1 more source

3D‐Printed Multidimensional Bionic Mg‐MC/PLGA Composite for Tailored Repair of Segmental Long Bone Defects

Advanced Healthcare Materials, EarlyView.
This study develops 3D‐printed Mg‐MC/PLGA scaffolds with varying Mg concentrations (0–20%). The 5% Mg scaffold shows optimal cytocompatibility, osteogenic activity in vitro, and significantly enhances bone regeneration in rabbits, improving bone volume and mechanical strength.
Shihang Liu, Shuai Zhou, Tingting Zou, Guangzhao Hou, Qian Xiao, Lin Li, Jianjun Yang, Wei Chen, Yingze Zhang, Hongzhi Lv   +9 more
wiley   +1 more source