The research demonstrates a Mesenchymal Stem Cell‐inspired microneedle platform (MSCi@MN) that addresses chronic diabetic wounds by combining MSC‐derived extracellular nanovesicles (NV)–DNA conjugates in microneedle tips with photothermal MXene in the patch layer.
Chan Ho Moon +21 more
wiley +1 more source
Modulation of the blood-brain barrier permeability by patient-derived glioblastoma stem cell secretome. [PDF]
Sica FS +11 more
europepmc +1 more source
Spatially Controlled 3‐D Multiplexed Aptamer Patterning in Hydrogels
A hydrogel platform based on norbornene‐functionalized polyvinyl alcohol enables high‐resolution, 3‐D multiplexed patterning of DNA aptamers via two‐photon polymerization. Two distinct aptamers are covalently immobilized with single micron‐scale precision across the x, y, and z dimensions.
Kevin Roost +9 more
wiley +1 more source
Shear stress-triggered adenosine triphosphate regulates angiogenic properties of human periodontal ligament stem cells. [PDF]
Kyawsoewin M +9 more
europepmc +1 more source
Citrate‐Enhanced PCL Scaffolds for Bone Tissue Engineering
This study investigates citrate‐enhanced polycaprolactone (PCL) scaffolds designed for bone tissue engineering. Utilizing 3D printing technology, four scaffold patterns (triple hexagon, grid, gyroid, zigzag) are evaluated for mechanical properties, cellular proliferation, osteogenic differentiation, and gene expression.
Muge Musmula +6 more
wiley +1 more source
Single-Cell Transcriptomics Reveals a Multi-Compartmental Cellular Cascade Underlying Elahere-Induced Ocular Toxicity in Rats. [PDF]
Zhang J +11 more
europepmc +1 more source
Live Quantitative Characterization for Stem Cell Biomechanics
These findings demonstrate an accessible technique for real‐time, high‐resolution mechanical mapping of live stem cells, without the use of specialised probes or advanced modelling techniques. This approach provides direct insight into localised cytoskeletal dynamics under chemical treatment and holds potential for broader application in understanding ...
Kaiwen Zhang +5 more
wiley +1 more source
Interactions of Hematopoietic and Associated Mesenchymal Stem Cell Populations in the Bone Marrow Microenvironment, In Vivo and In Vitro Model. [PDF]
Bačenková D +4 more
europepmc +1 more source
4D Bioprinted Self‐Folding Scaffolds Enhance Cartilage Formation in the Engineering of Trachea
A bilayer self‐folding scaffold, triggerable by humidity, is fabricated via 4D bioprinting for trachea engineering. An analytical model is derived to predict its radius of curvature, enabling its scalability. Cartilage progenitor cells seeded on the scaffold perceive scaffold final curvature and react to it, by enhancing the upregulation of pro ...
Irene Chiesa +4 more
wiley +1 more source
Cross-organ protection of MSC-derived extracellular vesicles in ischemia-reperfusion injury: angiogenic synergy in kidney, brain, and heart. [PDF]
Lai Z, Li D, Luo C, Qiu Q, Li R, Dai M.
europepmc +1 more source

