Results 71 to 80 of about 430,240 (358)

Chorioallantoic membrane assay as model for angiogenesis in tissue engineering : focus on stem cells [PDF]

, 2020
Tissue engineering aims to structurally and functionally regenerate damaged tissues, which requires the formation of new blood vessels that supply oxygen and nutrients by the process of angiogenesis.
Bronckaers, Annelies, De Spiegelaere, Ward, Lambrichts, Ivo, Lo Monaco, Melissa, Merckx, Greet, Tay, Hanna, van Zandvoort, Marc   +6 more
core   +3 more sources

Endothelial Differentiation of Embryonic Stem Cells [PDF]

, 2011
Embryonic stem (ES) cells are a rich source of multiple different cell types of diverse lineages. Significant advances have recently been made in our understanding of the molecular mechanisms by which ES cells differentiate into endothelial cells.
openaire   +3 more sources

Endothelial potential of human embryonic stem cells

Blood, 2007
Abstract Growing interest in using endothelial cells for therapeutic purposes has led to exploring human embryonic stem cells as a potential source for endothelial progenitor cells. Embryonic stem cells are advantageous when compared with other endothelial cell origins, due to their high proliferation capability, pluripotency, and low ...
Robert Langer, Shulamit Levenberg, Yaara Basevitch, Janet Zoldan   +3 more
openaire   +4 more sources

Goodbye flat lymphoma biology

FEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria, Cèlia Dobaño‐López, Patricia Pérez‐Galán, Christine Bezombes   +3 more
wiley   +1 more source

Endothelial cell-specific expression of serine/threonine kinase 11 modulates dendritic cell differentiation

Nature Communications, 2022
In the bone marrow, dendritic cell development is governed by supporting cells, such as endothelial cells. Here authors show that expression of serine/threonine kinase 11 in endothelial cells regulates differentiation of dendritic cell precursors via ...
Qiang Zhao, Young-Min Han, Ping Song, Zhixue Liu, Zuyi Yuan, Ming-Hui Zou   +5 more
doaj   +1 more source

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

FEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona, Carlo M. Bergamini, Carlo Ferrari, Stefano Volinia, Nicoletta Bianchi   +4 more
wiley   +1 more source

Endothelial cells instruct liver specification of embryonic stem cell-derived endoderm through endothelial VEGFR2 signaling and endoderm epigenetic modifications

Stem Cell Research, 2018
Liver organogenesis requires complex cell-cell interactions between hepatic endoderm cells and adjacent cell niches. Endothelial cells are key players for endoderm hepatic fate decision. We previously demonstrated that the endothelial cell niche promotes
Songyan Han, Christopher Tan, Junjun Ding, Jianlong Wang, Avi Ma'ayan, Valerie Gouon-Evans   +5 more
doaj   +1 more source

Co-Emergence of Specialized Endothelial Cells from Embryonic Stem Cells. [PDF]

, 2018
A well-formed and robust vasculature is critical to the health of most organ systems in the body. However, the endothelial cells (ECs) forming the vasculature can exhibit a number of distinct functional subphenotypes like arterial or venous ECs, as well ...
Douglas, Simone A, Fan, Yuhong, Kumar, Ashwath, Lin, Zhiqiang, Madfis, Nicole, McCloskey, Kara E, Platt, Manu O   +6 more
core   +1 more source

Identification of the initial molecular changes in response to circulating angiogenic cells-mediated therapy in critical limb ischemia [PDF]

, 2020
BackgroundCritical limb ischemia (CLI) constitutes the most aggressive form of peripheral arterial occlusive disease, characterized by the blockade of arteries supplying blood to the lower extremities, significantly diminishing oxygen and nutrient supply.
A Carrizzo, A Limbourg, A Schroll, A Taguchi, A Zampetaki, AI Khan, AL Hemdahl, C Hu, C Kalka, C Seignez, C Xia, CH Yoon, D Sukmawati, DH Walter, DM Dunlea, DN Prater, E Chavakis, EB Jude, EC Watson, EE Vaughan, EL Simpson, F Du, F Sabatier, F Vinchi, FG Fowkes, FM Vega, G Cao, G Dragneva, GO Ouma, H Chen, HH Chopra, J Patel, J Rehman, J Zhang, JA Smith, JA Vizcaino, JG Tidball, JK Meisner, JL Anderson, JL Dong, JP Cooke, JX Yang, JY Kim, K Banno, K Funakoshi, L Bao, L Norgren, L Wu, LJ Druhan, M Hassanpour, M Qadura, M Rahmani, M Rigato, MS Conte, N Edwards, P Sangwung, Q Dai, Q Xie, R Donato, R Lara-Hernandez, R Tanaka, RC Savani, RH Lee, RJ Medina, RW Sprengers, S Hazarika, S Janciauskiene, S Nolan, SH Ko, SL Hsu, SM Krishna, SW Kim, T Asahara, UJ Sachs, V Abella, V Weel van, W Song, WC Shen, X Wang, X Zhou, Y Fujita, Y Ye, Z Yang   +82 more
core   +1 more source

Tumor endothelial cells have features of adult stem cells [PDF]

Cell Cycle, 2009
We recently reported that prostate tumor-specific endothelial cells had features of mesenchymal stem cells and could transdifferentiate to form cartilage and bone-like tissues. Plasticity in the tumor vasculature may be related to well-known tumor blood vessel abnormalities and could underlie an intrinsic adaptive mechanism in tumor endothelial cells ...
Andrew C. Dudley, Michael Klagsbrun
openaire   +3 more sources