Results 11 to 20 of about 11,132 (227)

Risk factors of incomplete endothelialization after left atrial appendage occlusion in patients with atrial fibrillation

Archives of Medical Science
Introduction We aimed to investigate the risk factors of incomplete device endothelialization (IDE) following left atrial appendage occlusion (LAAO) and provide a nomogram model for predicting the risks of IDE in patients with atrial fibrillation (AF ...
Jia-Min Chen, Zhong-Bao Ruan, Ge-Cai Chen, Jun-Guo Zhu, Yin Ren, Li Zhu   +5 more
doaj   +2 more sources

Evaluation of endothelialization of an occluder device with cardiac computed tomography and assessment of the pathological validation.

PLoS ONE
BackgroundAssessing the endothelialization of occlusive devices noninvasively remains a challenge. Cardiac computed tomography angiography (CTA) can be employed to evaluate device endothelialization based on contrast uptake within the occluder ...
Ang Liu, Xuejing Duan, Ke Wang, Hongguang Fan, Li Li, Chaowu Yan   +5 more
doaj   +2 more sources

From Fiber Bundles to Architected Membranes: Triply Periodic Minimal Surface Architectures for Biohybrid Artificial Lungs. [PDF]

Adv Mater
Additively manufactured triply periodic minimal surface (TPMS) membranes offer an architecture‐driven alternative to hollow fiber bundles in artificial lungs. Multiphysics simulations and endothelialized prototypes show that the 3D‐printable membrane architecture improves gas exchange, blood flow distribution, and hemocompatibility, enabling ...
Pflaum M, Barbian KP, Neuhaus F, Sitarz G, Nölke C, Jansen SV, Linkhorst J, Hirschwald LT, Brosch S, Certa C, Steinseifer U, Wessling M, Arens J, Ruhparwar A, Wiegmann B.   +14 more
europepmc   +2 more sources

Biofunctionalized Decellularized Tissue-Engineered Heart Valve with Mesoporous Silica Nanoparticles for Controlled Release of VEGF and RunX2-siRNA against Calcification

Bioengineering, 2023
The goal of tissue-engineered heart valves (TEHV) is to replace normal heart valves and overcome the shortcomings of heart valve replacement commonly used in clinical practice.
Wenpeng Yu, Xiaowei Zhu, Jichun Liu, Jianliang Zhou   +3 more
doaj   +1 more source

Endothelial mechanobiology [PDF]

APL Bioengineering, 2020
Lining the luminal surface of the vasculature, endothelial cells (ECs) are in direct contact with and differentially respond to hemodynamic forces depending on their anatomic location. Pulsatile shear stress (PS) is defined by laminar flow and is predominantly located in straight vascular regions, while disturbed or oscillatory shear stress (OS) is ...
Ming He, Marcy Martin, Traci Marin, Zhen Chen, Brendan Gongol   +4 more
openaire   +3 more sources

Endothelial Functions [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 2017
The endothelium plays important roles in modulating vascular tone by synthesizing and releasing a variety of endothelium-derived relaxing factors, including vasodilator prostaglandins, NO, and endothelium-dependent hyperpolarization factors, as well as endothelium-derived contracting factors.
Shigeo, Godo, Hiroaki, Shimokawa
openaire   +2 more sources

Free-aldehyde neutralized and oligohyaluronan loaded bovine pericardium with improved anti-calcification and endothelialization for bioprosthetic heart valves

Frontiers in Bioengineering and Biotechnology, 2023
The number of patients with valvular heart disease is increasing yearly, and valve replacement is the most effective treatment, during which bioprosthetic heart valves (BHVs) are the most widely used.
Yuhong Liu, Yuhong Liu, Chunyang Chen, Chunyang Chen, Ting Lu, Ting Lu, Sixi Liu, Sixi Liu, Zhongshi Wu, Zhongshi Wu, Zhenjie Tang, Zhenjie Tang   +11 more
doaj   +1 more source

Endothelial aging [PDF]

Cardiovascular Research, 2005
Aging is considered to be the major risk factor for the development of atherosclerosis and, therefore, for coronary artery disease. Apart from age-associated remodeling of the vascular wall, which includes luminal enlargement, intimal and medial thickening, and increased vascular stiffness, endothelial function declines with age.
Ralf P, Brandes, Ingrid, Fleming, Rudi, Busse   +2 more
openaire   +2 more sources

Dynamic, nondestructive imaging of a bioengineered vascular graft endothelium. [PDF]

PLoS ONE, 2013
Bioengineering of vascular grafts holds great potential to address the shortcomings associated with autologous and conventional synthetic vascular grafts used for small diameter grafting procedures.
Bryce M Whited, Matthias C Hofmann, Peng Lu, Yong Xu, Christopher G Rylander, Ge Wang, Etai Sapoznik, Tracy Criswell, Sang Jin Lee, Shay Soker, Marissa Nichole Rylander   +10 more
doaj   +1 more source

Biohybrid lung Development: Towards Complete Endothelialization of an Assembled Extracorporeal Membrane Oxygenator

Bioengineering, 2023
Towards the establishment of a long-term lung-assist device to be used both as a bridge and as an alternative to lung transplantation according to final destination therapy, we develop the biohybrid lung (BHL) on the technical basis of contemporary ...
Hussam Almesto Alabdullh, Michael Pflaum, Marisa Mälzer, Marcel Kipp, Hossein Naghilouy-Hidaji, Denise Adam, Christian Kühn, Russlan Natanov, Adelheid Niehaus, Axel Haverich, Bettina Wiegmann   +10 more
doaj   +1 more source